UPB
Upstream Bio, Inc.
NASDAQ: UPB · HEALTHCARE · BIOTECHNOLOGY
$9.19
-3.36% today
Updated 2026-04-29
Market cap
$500.12M
P/E ratio
—
P/S ratio
175.23x
EPS (TTM)
$-2.66
Dividend yield
—
52W range
$7 – $34
Volume
1.0M
Upstream Bio, Inc. (UPB) Financial statements
SEC filings — annual and quarterly data.
Profit margin
0.00%
Operating margin
-6,911.00%
ROE
-35.40%
ROA
-24.00%
Debt/equity
—
Margin trends — annual
Gross margin Operating margin Profit margin
| Year | Revenue | Net income | Gross margin | Op. margin | Profit margin |
|---|---|---|---|---|---|
| 2022 | $1.21M | $-23.87M | 100.00% | -1,972.69% | -1,969.31% |
| 2023 | $2.38M | $-20.54M | 100.00% | -1,685.46% | -862.90% |
| 2024 | $2.37M | $-62.81M | 100.00% | -3,281.18% | -2,650.04% |
| 2025 | $2.85M | $-143.44M | 93.41% | -5,618.82% | -5,026.03% |