UPB
Upstream Bio, Inc.
NASDAQ: UPB · HEALTHCARE · BIOTECHNOLOGY
$9.19
-3.36% today
Updated 2026-04-29
Market cap
$500.12M
P/E ratio
—
P/S ratio
175.23x
EPS (TTM)
$-2.66
Dividend yield
—
52W range
$7 – $34
Volume
1.0M
Upstream Bio, Inc. (UPB) Financial statements
SEC filings — annual and quarterly data.
Cash flow — annual
| Item | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|
| Operating cash flow | $-19.02M | $-37.93M | $-59.17M | $-133.28M |
| Capital expenditures | $82000.00 | $144000.00 | $511000.00 | $165000.00 |
| Depreciation | — | — | — | — |
| Stock-based comp | $1.28M | $3.43M | $6.00M | $10.33M |
| Free cash flow | $-19.10M | $-38.07M | $-59.68M | $-133.44M |
| Investing cash flow | — | — | — | — |
| Financing cash flow | — | — | — | — |
| Dividends paid | — | — | — | — |
| Share repurchases | — | — | — | — |
| Debt repayment | — | — | — | — |
| Net change in cash | — | — | — | — |