SPRO
Spero Therapeutics Inc
NASDAQ: SPRO · HEALTHCARE · BIOTECHNOLOGY
$2.51
-0.79% today
Updated 2026-04-30
Market cap
$154.60M
P/E ratio
17.80
P/S ratio
2.31x
EPS (TTM)
$0.15
Dividend yield
—
52W range
$1 – $3
Volume
0.4M
WallStSmart proprietary scores
63
out of 100
Grade: C+
Hold
Investment rating
8.7
Growth
A5.0
Quality
C+7.5
Profitability
B+7.7
Valuation
B+—/9
Piotroski F-Score
—
—
Altman Z-Score
—
—
Industry rank
—
View all highly rated stocks (75+) →200 stocks currently score above 75
Price targets
Analyst target
$4.00
+59.36%
12-Month target
$2.91
+15.94%
Intrinsic (DCF)
$4.95
Margin of safety
+51.92%
Price chart
X-Ray snapshot
Strengths
+ Revenue growth 174.50% QoQ
+ 51.92% below intrinsic value
Risks
- Negative free cash flow $-8.35M
Key financials
Revenue Net Income Free Cash Flow
| Metric | 2022 | 2023 | 2024 | 2025 | TTM |
|---|---|---|---|---|---|
| Revenue | $48.58M | $103.78M | $47.98M | $59.62M | $66.80M |
| Net income | $-46.41M | $22.81M | $-68.57M | $8.57M | $31.52M |
| EPS | — | — | — | — | $0.15 |
| Free cash flow | $-7.73M | $-32.99M | $-23.44M | $-12.62M | $-8.35M |
| Profit margin | -95.55% | 21.98% | -142.91% | 14.38% | 12.80% |
Peer comparison
Smart narrative
Spero Therapeutics Inc trades at $2.51. representing a P/E of 17.80x trailing earnings. Our Smart Value Score of 63/100 indicates the stock is good. TTM revenue stands at $66.80M. with profit margins at 12.80%. Our DCF model estimates intrinsic value at $4.95.
Frequently asked questions
What is Spero Therapeutics Inc's stock price?
Spero Therapeutics Inc (SPRO) trades at $2.51.
Is Spero Therapeutics Inc overvalued?
Smart Value Score 63/100 (Grade C+, Hold). DCF value $4.95.
What is the price target of Spero Therapeutics Inc (SPRO)?
The analyst target price is $4.00, representing +59.4% upside from the current price of $2.51.
What is the intrinsic value of Spero Therapeutics Inc (SPRO)?
Based on our DCF model, intrinsic value is $4.95, a +51.9% margin of safety versus $2.51.
What is Spero Therapeutics Inc's revenue?
TTM revenue is $66.80M.
Company info
SectorHEALTHCARE
IndustryBIOTECHNOLOGY
CountryUSA
ExchangeNASDAQ
CurrencyUSD
Quick metrics
P/S ratio2.31x
ROE16.30%
Beta1.45
50D MA$2.49
200D MA$2.31
Shares out0.06B
Float0.05B
Short ratio—
Avg volume0.4M
Performance
1 week—
1 month—
3 months—
YTD—
1 year—
3 years—
5 years—