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SEPN

Septerna, Inc. Common Stock

NASDAQ: SEPN · HEALTHCARE · BIOTECHNOLOGY

$23.76
+1.32% today

Updated 2026-04-30

Market cap
$1.05B
P/E ratio
P/S ratio
22.92x
EPS (TTM)
$-1.10
Dividend yield
52W range
$6 – $33
Volume
0.3M

Septerna, Inc. Common Stock (SEPN) Financial statements

SEC filings — annual and quarterly data.

Profit margin
-106.40%
Operating margin
-66.40%
ROE
-12.20%
ROA
-9.59%
Debt/equity
0.06x

Margin trends — annual

Gross margin Operating margin Profit margin
YearRevenueNet incomeGross marginOp. marginProfit margin
2022$0.00$-27.68M
2023$151000.00$4.18M100.00%1,374.17%2,768.21%
2024$1.07M$-71.80M100.00%-7,518.42%-6,678.88%
2025$45.95M$-48.88M100.00%-175.83%-106.37%