SEPN
Septerna, Inc. Common Stock
NASDAQ: SEPN · HEALTHCARE · BIOTECHNOLOGY
$23.76
+1.32% today
Updated 2026-04-30
Market cap
$1.05B
P/E ratio
—
P/S ratio
22.92x
EPS (TTM)
$-1.10
Dividend yield
—
52W range
$6 – $33
Volume
0.3M
WallStSmart proprietary scores
33
out of 100
Grade: F
Strong Sell
Investment rating
6.3
Growth
B9.0
Quality
A+2.0
Profitability
F5.0
Valuation
C+5/9
Piotroski F-Score
Moderate
7.0
Altman Z-Score
Safe zone
—
Industry rank
—
View all highly rated stocks (75+) →206 stocks currently score above 75
Price targets
Analyst target
$44.43
+86.99%
12-Month target
—
—
Intrinsic (DCF)
—
Margin of safety
—
1 Strong Buy7 Buy0 Hold0 Sell0 Strong Sell
Price chart
X-Ray snapshot
Strengths
+ Altman Z 6.96 — safe zone
+ Revenue growth 11,276.00% QoQ
+ Debt/equity 0.06x — low leverage
Risks
- Thin margins at -106.40%
- Negative free cash flow $-15.05M
Key financials
Revenue Net Income Free Cash Flow
| Metric | 2022 | 2023 | 2024 | 2025 | TTM |
|---|---|---|---|---|---|
| Revenue | $0.00 | $151000.00 | $1.07M | $45.95M | $45.95M |
| Net income | $-27.68M | $4.18M | $-71.80M | $-48.88M | $-10.74M |
| EPS | — | — | — | — | $-1.10 |
| Free cash flow | $-24.59M | $-41.60M | $-69.57M | $109.67M | $-15.05M |
| Profit margin | — | 2,768.21% | -6,678.88% | -106.37% | -106.40% |
Peer comparison
Smart narrative
Septerna, Inc. Common Stock trades at $23.76. Our Smart Value Score of 33/100 indicates the stock is weak. The company scores 5/9 on the Piotroski F-Score. With an Altman Z-Score of 6.96, it sits in the safe zone. TTM revenue stands at $45.95M. with profit margins at -106.40%.
Frequently asked questions
What is Septerna, Inc. Common Stock's stock price?
Septerna, Inc. Common Stock (SEPN) trades at $23.76.
Is Septerna, Inc. Common Stock overvalued?
Smart Value Score 33/100 (Grade F, Strong Sell).
What is the price target of Septerna, Inc. Common Stock (SEPN)?
The analyst target price is $44.43, representing +87.0% upside from the current price of $23.76.
What is Septerna, Inc. Common Stock's revenue?
TTM revenue is $45.95M.
Piotroski F-Score?
5/9 — moderate financial health.
Altman Z-Score?
6.96 — safe zone.
Company info
SectorHEALTHCARE
IndustryBIOTECHNOLOGY
CountryUSA
ExchangeNASDAQ
CurrencyUSD
Quick metrics
P/S ratio22.92x
ROE-12.20%
Beta—
50D MA$25.90
200D MA$21.83
Shares out0.04B
Float0.02B
Short ratio—
Avg volume0.3M
Performance
1 week—
1 month—
3 months—
YTD—
1 year—
3 years—
5 years—