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AXSM

Axsome Therapeutics Inc

NASDAQ: AXSM · HEALTHCARE · BIOTECHNOLOGY

$216.47
+0.36% today

Updated 2026-06-05

Market cap
$13.13B
P/E ratio
P/S ratio
18.54x
EPS (TTM)
$-3.73
Dividend yield
52W range
$96 – $258
Volume
0.7M

Axsome Therapeutics Inc (AXSM) Financial statements

SEC filings — annual and quarterly data.

Profit margin
-28.69%
Operating margin
-26.51%
ROE
-344.96%
ROA
-16.80%
Debt/equity
3.97x

Margin trends — annual

Gross margin Operating margin Profit margin
YearRevenueNet incomeGross marginOp. marginProfit margin
2013$-2.17M
2014$0.00$-6.00M
2015$0.00$-12.21M
2016$0.00$-27.20M
2017$0.00$-28.94M
2018$0.00$-30.97M
2019$0.00$-68.35M
2020$0.00$-102.90M
2021$8.82M$-134.94M-13.10%-1,413.95%-1,530.01%
2022$50.04M$-187.13M89.61%-359.33%-373.99%
2023$270.60M$-239.24M90.37%-85.67%-88.41%
2024$385.69M$-287.22M91.37%-72.74%-74.47%
2025$638.50M$-183.17M92.56%-26.51%-28.69%

Frequently asked questions

What is Axsome Therapeutics Inc's revenue?

Axsome Therapeutics Inc's trailing twelve-month revenue is $708.24M, and consensus projects about $5.12B by 2030. Revenue is the top line the whole model builds on, and at this scale the question shifts from how fast it grows to whether margins hold as it compounds.

How profitable is AXSM?

In its most recent fiscal year, AXSM ran a gross margin of 92.56%, an operating margin of -26.51%, and a net margin of -28.69%. Margins this high mean most of each extra dollar of revenue drops through to profit, which is the signature of real pricing power.

How much free cash flow does AXSM generate?

AXSM produced $-93.89M in free cash flow in its most recent fiscal year. Free cash flow is what is left after running and reinvesting in the business, and it is the cash that actually funds buybacks, dividends, and a stronger balance sheet.

Is AXSM's balance sheet healthy?

AXSM holds $322.93M in cash and equivalents against $117.75M in long-term debt, on $88.30M of shareholder equity. Cash on hand exceeds long-term debt, so the balance sheet adds little financial risk to the thesis.