AXSM
Axsome Therapeutics Inc
NASDAQ: AXSM · HEALTHCARE · BIOTECHNOLOGY
$143.51
+0.92% today
Updated 2026-10-28
Market cap
$8.47B
P/E ratio
—
P/S ratio
10.91x
EPS (TTM)
$-3.74
Dividend yield
—
52W range
$124 – $260
Volume
0.8M
Axsome Therapeutics Inc (AXSM) Insider transactions
Net insider activity
Net selling (851,108 shares)
Buy transactions
35
Sell transactions
65
All transactions
| Date | Insider | Title | Type | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-09-03 | JACOBSON, MARK L. | Chief Operating Officer | Sale | 10,000 | — | — |
| 2026-09-03 | JACOBSON, MARK L. | Chief Operating Officer | Sale | 10,000 | $208.65 | $2.09M |
| 2026-08-06 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 4,660 | — | — |
| 2026-08-06 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 4,660 | $213.95 | $997007.00 |
| 2026-08-05 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 45,004 | — | — |
| 2026-08-05 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Buy | 45,004 | $4.95 | $222769.80 |
| 2026-07-01 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 49,666 | — | — |
| 2026-07-01 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Buy | 49,666 | $4.95 | $245846.70 |
| 2026-06-11 | JEFFS, ROGER | Director | Sale | 286 | $249.12 | $71248.32 |
| 2026-06-10 | MAHONY, SUSAN | Director | Sale | 300 | $246.18 | $73854.00 |
| 2026-06-10 | JEFFS, ROGER | Director | Sale | 286 | $246.18 | $70407.48 |
| 2026-06-10 | COLEMAN, MARK | Director | Sale | 643 | $249.00 | $160107.00 |
| 2026-06-09 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 49,670 | — | — |
| 2026-06-09 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 49,670 | $241.01 | $11.97M |
| 2026-06-09 | PIZZIE, NICK | Chief Financial Officer | Sale | 33,000 | — | — |
| 2026-06-09 | PIZZIE, NICK | Chief Financial Officer | Sale | 33,000 | $240.09 | $7.92M |
| 2026-06-09 | MAHONY, SUSAN | Director | Sale | 300 | $237.21 | $71163.00 |
| 2026-06-08 | SAAD, MARK E | Director | Sale | 1,429 | — | — |
| 2026-06-08 | SAAD, MARK E | Director | Buy | 1,429 | — | — |
| 2026-06-08 | MAHONY, SUSAN | Director | Sale | 1,429 | — | — |
| 2026-06-08 | MAHONY, SUSAN | Director | Buy | 1,429 | — | — |
| 2026-06-08 | JEFFS, ROGER | Director | Sale | 1,429 | — | — |
| 2026-06-08 | JEFFS, ROGER | Director | Buy | 1,429 | — | — |
| 2026-06-08 | COLEMAN, MARK | Director | Sale | 1,429 | — | — |
| 2026-06-08 | COLEMAN, MARK | Director | Buy | 1,429 | — | — |
| 2026-06-05 | SAAD, MARK E | Director | Buy | 1,721 | — | — |
| 2026-06-05 | MAHONY, SUSAN | Director | Buy | 1,721 | — | — |
| 2026-06-05 | JEFFS, ROGER | Director | Buy | 1,721 | — | — |
| 2026-06-05 | COLEMAN, MARK | Director | Buy | 1,721 | — | — |
| 2026-06-02 | COLEMAN, MARK | Director | Sale | 5,537 | $223.39 | $1.24M |
| 2026-06-01 | COLEMAN, MARK | Director | Sale | 6,000 | $230.30 | $1.38M |
| 2026-05-29 | COLEMAN, MARK | Director | Sale | 6,000 | $233.46 | $1.40M |
| 2026-05-05 | JACOBSON, MARK L. | Chief Operating Officer | Sale | 233 | — | — |
| 2026-05-05 | JACOBSON, MARK L. | Chief Operating Officer | Sale | 233 | $228.18 | $53165.94 |
| 2026-05-04 | JACOBSON, MARK L. | Chief Operating Officer | Sale | 4,517 | — | — |
| 2026-05-04 | JACOBSON, MARK L. | Chief Operating Officer | Sale | 4,517 | $227.94 | $1.03M |
| 2026-04-22 | MAIZEL, ARI | Chief Commercial Officer | Sale | 7,500 | — | — |
| 2026-04-22 | MAIZEL, ARI | Chief Commercial Officer | Sale | 7,500 | $182.42 | $1.37M |
| 2026-04-21 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Buy | 24,081 | — | — |
| 2026-04-21 | PIZZIE, NICK | Chief Financial Officer | Buy | 8,188 | — | — |
| 2026-04-21 | MURDOCK, HUNTER R. | General Counsel | Buy | 7,224 | — | — |
| 2026-04-21 | MAIZEL, ARI | Chief Commercial Officer | Buy | 7,224 | — | — |
| 2026-04-21 | JACOBSON, MARK L. | Chief Operating Officer | Buy | 8,669 | — | — |
| 2026-02-26 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Buy | 54,623 | — | — |
| 2026-02-26 | PIZZIE, NICK | Chief Financial Officer | Buy | 18,570 | — | — |
| 2026-02-26 | MURDOCK, HUNTER R. | General Counsel | Buy | 16,385 | — | — |
| 2026-02-26 | MAIZEL, ARI | Chief Commercial Officer | Buy | 16,385 | — | — |
| 2026-02-26 | JACOBSON, MARK L. | Chief Operating Officer | Sale | 35,378 | — | — |
| 2026-02-26 | JACOBSON, MARK L. | Chief Operating Officer | Buy | 19,663 | — | — |
| 2026-02-26 | JACOBSON, MARK L. | Chief Operating Officer | Sale | 35,378 | $161.88 | $5.73M |
| 2026-02-26 | COLEMAN, MARK | Director | Sale | 25,000 | $161.11 | $4.03M |
| 2026-02-23 | COLEMAN, MARK | Director | Sale | 6,250 | — | — |
| 2026-02-23 | COLEMAN, MARK | Director | Buy | 6,250 | $4.95 | $30937.50 |
| 2026-02-20 | COLEMAN, MARK | Director | Sale | 12,485 | — | — |
| 2026-02-20 | COLEMAN, MARK | Director | Buy | 12,485 | $4.95 | $61800.75 |
| 2026-02-10 | COLEMAN, MARK | Director | Sale | 5,193 | — | — |
| 2026-02-10 | COLEMAN, MARK | Director | Buy | 5,193 | $8.02 | $41647.86 |
| 2026-02-02 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 32,410 | — | — |
| 2026-02-02 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 32,410 | $185.60 | $6.02M |
| 2026-01-22 | PIZZIE, NICK | Chief Financial Officer | Sale | 12,000 | — | — |
| 2026-01-22 | PIZZIE, NICK | Chief Financial Officer | Sale | 12,000 | $187.92 | $2.26M |
| 2026-01-21 | MAIZEL, ARI | Chief Commercial Officer | Sale | 7,500 | — | — |
| 2026-01-21 | MAIZEL, ARI | Chief Commercial Officer | Buy | 7,500 | $70.73 | $530475.00 |
| 2026-01-07 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 31,261 | — | — |
| 2026-01-07 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Buy | 31,261 | $8.02 | $250713.22 |
| 2026-01-06 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 29,450 | — | — |
| 2026-01-06 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Buy | 29,450 | $8.02 | $236189.00 |
| 2026-01-05 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 78,703 | — | — |
| 2026-01-05 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 78,703 | $171.28 | $13.48M |
| 2025-12-31 | SAAD, MARK E | Director | Sale | 31,346 | — | — |
| 2025-12-31 | SAAD, MARK E | Director | Sale | 6,231 | — | — |
| 2025-12-31 | SAAD, MARK E | Director | Sale | 31,346 | $165.18 | $5.18M |
| 2025-12-31 | SAAD, MARK E | Director | Sale | 6,231 | $165.18 | $1.03M |
| 2025-12-04 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 10,558 | — | — |
| 2025-12-04 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 10,558 | $148.18 | $1.56M |
| 2025-12-03 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 20,163 | — | — |
| 2025-12-03 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 20,163 | $146.94 | $2.96M |
| 2025-12-02 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 49,252 | — | — |
| 2025-12-02 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 49,252 | $144.59 | $7.12M |
| 2025-11-05 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 21,775 | — | — |
| 2025-11-05 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Buy | 21,775 | $8.02 | $174635.50 |
| 2025-11-04 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 50,459 | — | — |
| 2025-11-04 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Buy | 50,459 | $8.02 | $404681.18 |
| 2025-11-03 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 91,705 | — | — |
| 2025-11-03 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 91,705 | $132.34 | $12.14M |
| 2025-10-08 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 12,774 | — | — |
| 2025-10-08 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Buy | 12,774 | $8.02 | $102447.48 |
| 2025-10-07 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 13,390 | — | — |
| 2025-10-07 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Buy | 13,390 | $8.02 | $107387.80 |
| 2025-10-06 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 19,220 | — | — |
| 2025-10-06 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Buy | 19,220 | $8.02 | $154144.40 |
| 2025-09-22 | JACOBSON, MARK L. | Chief Operating Officer | Sale | 10,000 | — | — |
| 2025-09-22 | JACOBSON, MARK L. | Chief Operating Officer | Buy | 10,000 | $2.85 | $28500.00 |
| 2025-09-16 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Sale | 19,719 | — | — |
| 2025-09-16 | TABUTEAU, HERRIOT | Director, Chief Executive Officer, 10% Owner | Buy | 19,719 | $8.02 | $158146.38 |
| 2025-09-16 | JACOBSON, MARK L. | Chief Operating Officer | Sale | 25,000 | — | — |
| 2025-09-16 | JACOBSON, MARK L. | Chief Operating Officer | Sale | 15,000 | — | — |
| 2025-09-16 | JACOBSON, MARK L. | Chief Operating Officer | Sale | 40,000 | $114.23 | $4.57M |
| 2025-09-16 | JACOBSON, MARK L. | Chief Operating Officer | Buy | 25,000 | $4.95 | $123750.00 |
| 2025-09-16 | JACOBSON, MARK L. | Chief Operating Officer | Buy | 15,000 | $4.85 | $72750.00 |
Frequently asked questions
Are AXSM insiders buying or selling?
Over the transactions on record, AXSM insiders have been net sellers, with about $95.96M in stock sold across 65 sales, against 17 open-market purchases.
Does insider selling at AXSM mean the stock will fall?
Not by itself. Most executive selling is pre-scheduled through 10b5-1 plans filed months in advance, and insiders sell for diversification, taxes, and liquidity far more often than out of any view on the price. Insider buying is the stronger signal, especially when several insiders buy around the same time, because there is usually only one reason to put personal cash into the stock.
Which AXSM insiders are selling the most?
Recent selling is concentrated in a few names. TABUTEAU, HERRIOT accounts for the largest share on record, with about $56.25M sold. Selling by one or two individuals matters less than broad selling across the whole leadership team, which is the pattern worth watching.