ALNY
Alnylam Pharmaceuticals Inc
NASDAQ: ALNY · HEALTHCARE · BIOTECHNOLOGY
$284.84
-0.19% today
Updated 2026-06-05
Market cap
$37.76B
P/E ratio
70.89
P/S ratio
8.81x
EPS (TTM)
$3.99
Dividend yield
—
52W range
$282 – $496
Volume
1.1M
Alnylam Pharmaceuticals Inc (ALNY) Insider transactions
Net insider activity
Net buying (14,297 shares)
Buy transactions
23
Sell transactions
77
All transactions
| Date | Insider | Title | Type | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-06-01 | PYOTT, DAVID E I | Director | Sale | 3,830 | — | — |
| 2026-06-01 | PYOTT, DAVID E I | Director | Buy | 3,830 | — | — |
| 2026-06-01 | PYOTT, DAVID E I | Director | Sale | 1,222 | $299.87 | $366441.14 |
| 2026-06-01 | PYOTT, DAVID E I | Director | Sale | 1,175 | $298.91 | $351219.25 |
| 2026-06-01 | PYOTT, DAVID E I | Director | Sale | 921 | $297.71 | $274190.91 |
| 2026-06-01 | PYOTT, DAVID E I | Director | Sale | 495 | $300.72 | $148856.40 |
| 2026-06-01 | PYOTT, DAVID E I | Director | Sale | 17 | $302.65 | $5145.05 |
| 2026-06-01 | CRAVATT, BENJAMIN | Director | Buy | 4,393 | — | — |
| 2026-05-20 | SIGAL, CHARLES ELLIOTT | Director | Buy | 1,441 | — | — |
| 2026-05-20 | SIGAL, CHARLES ELLIOTT | Director | Buy | 671 | — | — |
| 2026-05-20 | SCHULMAN, AMY W | Director | Buy | 1,802 | — | — |
| 2026-05-20 | SCHULMAN, AMY W | Director | Buy | 838 | — | — |
| 2026-05-20 | REITAN, COLLEEN F | Director | Buy | 1,441 | — | — |
| 2026-05-20 | REITAN, COLLEEN F | Director | Buy | 671 | — | — |
| 2026-05-20 | PYOTT, DAVID E I | Director | Buy | 1,441 | — | — |
| 2026-05-20 | PYOTT, DAVID E I | Director | Buy | 671 | — | — |
| 2026-05-20 | KELLOGG, PETER N | Director | Buy | 1,441 | — | — |
| 2026-05-20 | KELLOGG, PETER N | Director | Buy | 671 | — | — |
| 2026-05-20 | HAMBURG, MARGARET A | Director | Buy | 1,441 | — | — |
| 2026-05-20 | HAMBURG, MARGARET A | Director | Buy | 671 | — | — |
| 2026-05-20 | BRANDICOURT, OLIVIER | Director | Buy | 1,441 | — | — |
| 2026-05-20 | BRANDICOURT, OLIVIER | Director | Buy | 671 | — | — |
| 2026-05-20 | AUSIELLO, DENNIS A | Director | Buy | 1,441 | — | — |
| 2026-05-20 | AUSIELLO, DENNIS A | Director | Buy | 671 | — | — |
| 2026-05-20 | ARBUCKLE, STUART A | Director | Buy | 1,441 | — | — |
| 2026-05-20 | ARBUCKLE, STUART A | Director | Buy | 671 | — | — |
| 2026-05-13 | SCHULMAN, AMY W | Director | Sale | 11,250 | — | — |
| 2026-05-13 | SCHULMAN, AMY W | Director | Buy | 11,250 | $70.20 | $789750.00 |
| 2026-04-06 | MCLAUGHLIN, MELISSA | Chief Human Resources Officer | Sale | 909 | $329.76 | $299751.84 |
| 2026-04-06 | MCLAUGHLIN, MELISSA | Chief Human Resources Officer | Sale | 829 | $330.46 | $273951.34 |
| 2026-04-06 | MCLAUGHLIN, MELISSA | Chief Human Resources Officer | Sale | 293 | $331.89 | $97243.77 |
| 2026-04-06 | MCLAUGHLIN, MELISSA | Chief Human Resources Officer | Sale | 199 | $333.94 | $66454.06 |
| 2026-04-06 | MCLAUGHLIN, MELISSA | Chief Human Resources Officer | Sale | 56 | $320.14 | $17927.84 |
| 2026-04-02 | MCLAUGHLIN, MELISSA | Chief Human Resources Officer | Sale | 359 | $317.44 | $113960.96 |
| 2026-04-02 | MCLAUGHLIN, MELISSA | Chief Human Resources Officer | Sale | 265 | $316.61 | $83901.65 |
| 2026-04-02 | MCLAUGHLIN, MELISSA | Chief Human Resources Officer | Sale | 245 | $322.86 | $79100.70 |
| 2026-04-02 | MCLAUGHLIN, MELISSA | Chief Human Resources Officer | Sale | 224 | $321.64 | $72047.36 |
| 2026-04-02 | MCLAUGHLIN, MELISSA | Chief Human Resources Officer | Sale | 209 | $318.47 | $66560.23 |
| 2026-04-02 | MCLAUGHLIN, MELISSA | Chief Human Resources Officer | Sale | 147 | $320.62 | $47131.14 |
| 2026-04-02 | MCLAUGHLIN, MELISSA | Chief Human Resources Officer | Sale | 86 | $319.69 | $27493.34 |
| 2026-04-02 | MCLAUGHLIN, MELISSA | Chief Human Resources Officer | Sale | 81 | $323.64 | $26214.84 |
| 2026-04-02 | MCLAUGHLIN, MELISSA | Chief Human Resources Officer | Sale | 8 | $325.49 | $2603.92 |
| 2026-03-05 | GARG, PUSHKAL | EVP Chief R&D | Sale | 740 | $323.55 | $239427.00 |
| 2026-03-05 | GARG, PUSHKAL | EVP Chief R&D | Sale | 654 | $322.33 | $210803.82 |
| 2026-03-05 | GARG, PUSHKAL | EVP Chief R&D | Sale | 510 | $324.59 | $165540.90 |
| 2026-03-05 | GARG, PUSHKAL | EVP Chief R&D | Sale | 500 | $326.08 | $163040.00 |
| 2026-03-05 | FITZGERALD, KEVIN JOSEPH | CSO & EVP, Head of Research | Sale | 233 | $323.25 | $75317.25 |
| 2026-03-05 | FITZGERALD, KEVIN JOSEPH | CSO & EVP, Head of Research | Sale | 153 | $326.24 | $49914.72 |
| 2026-03-05 | FITZGERALD, KEVIN JOSEPH | CSO & EVP, Head of Research | Sale | 148 | $324.60 | $48040.80 |
| 2026-03-05 | FITZGERALD, KEVIN JOSEPH | CSO & EVP, Head of Research | Sale | 124 | $321.81 | $39904.44 |
| 2026-03-04 | TANGULER, TOLGA | EVP, Chief Commercial Officer | Sale | 767 | $323.84 | $248385.28 |
| 2026-03-04 | TANGULER, TOLGA | EVP, Chief Commercial Officer | Sale | 350 | $323.01 | $113053.50 |
| 2026-03-04 | TANGULER, TOLGA | EVP, Chief Commercial Officer | Sale | 289 | $321.82 | $93005.98 |
| 2026-03-04 | TANGULER, TOLGA | EVP, Chief Commercial Officer | Sale | 272 | $324.88 | $88367.36 |
| 2026-03-04 | TANGULER, TOLGA | EVP, Chief Commercial Officer | Sale | 215 | $320.81 | $68974.15 |
| 2026-03-04 | TANGULER, TOLGA | EVP, Chief Commercial Officer | Sale | 208 | $325.67 | $67739.36 |
| 2026-03-04 | TANGULER, TOLGA | EVP, Chief Commercial Officer | Sale | 106 | $319.03 | $33817.18 |
| 2026-03-04 | TANGULER, TOLGA | EVP, Chief Commercial Officer | Sale | 102 | $320.01 | $32641.02 |
| 2026-03-04 | POULTON, JEFFREY V. | EVP, Chief Financial Officer | Sale | 818 | $323.84 | $264901.12 |
| 2026-03-04 | POULTON, JEFFREY V. | EVP, Chief Financial Officer | Sale | 374 | $323.01 | $120805.74 |
| 2026-03-04 | POULTON, JEFFREY V. | EVP, Chief Financial Officer | Sale | 309 | $321.82 | $99442.38 |
| 2026-03-04 | POULTON, JEFFREY V. | EVP, Chief Financial Officer | Sale | 291 | $324.88 | $94540.08 |
| 2026-03-04 | POULTON, JEFFREY V. | EVP, Chief Financial Officer | Sale | 230 | $320.81 | $73786.30 |
| 2026-03-04 | POULTON, JEFFREY V. | EVP, Chief Financial Officer | Sale | 223 | $325.67 | $72624.41 |
| 2026-03-04 | POULTON, JEFFREY V. | EVP, Chief Financial Officer | Sale | 114 | $319.03 | $36369.42 |
| 2026-03-04 | POULTON, JEFFREY V. | EVP, Chief Financial Officer | Sale | 109 | $320.01 | $34881.09 |
| 2026-03-04 | GREENSTREET, YVONNE | Director, Chief Executive Officer | Sale | 973 | $323.84 | $315096.32 |
| 2026-03-04 | GREENSTREET, YVONNE | Director, Chief Executive Officer | Sale | 444 | $323.01 | $143416.44 |
| 2026-03-04 | GREENSTREET, YVONNE | Director, Chief Executive Officer | Sale | 368 | $321.82 | $118429.76 |
| 2026-03-04 | GREENSTREET, YVONNE | Director, Chief Executive Officer | Sale | 345 | $324.88 | $112083.60 |
| 2026-03-04 | GREENSTREET, YVONNE | Director, Chief Executive Officer | Sale | 274 | $320.81 | $87901.94 |
| 2026-03-04 | GREENSTREET, YVONNE | Director, Chief Executive Officer | Sale | 265 | $325.67 | $86302.55 |
| 2026-03-04 | GREENSTREET, YVONNE | Director, Chief Executive Officer | Sale | 135 | $319.03 | $43069.05 |
| 2026-03-04 | GREENSTREET, YVONNE | Director, Chief Executive Officer | Sale | 129 | $320.01 | $41281.29 |
| 2026-03-04 | GARG, PUSHKAL | EVP Chief R&D | Sale | 767 | $323.84 | $248385.28 |
| 2026-03-04 | GARG, PUSHKAL | EVP Chief R&D | Sale | 350 | $323.01 | $113053.50 |
| 2026-03-04 | GARG, PUSHKAL | EVP Chief R&D | Sale | 289 | $321.82 | $93005.98 |
| 2026-03-04 | GARG, PUSHKAL | EVP Chief R&D | Sale | 272 | $324.88 | $88367.36 |
| 2026-03-04 | GARG, PUSHKAL | EVP Chief R&D | Sale | 215 | $320.81 | $68974.15 |
| 2026-03-04 | GARG, PUSHKAL | EVP Chief R&D | Sale | 208 | $325.67 | $67739.36 |
| 2026-03-04 | GARG, PUSHKAL | EVP Chief R&D | Sale | 106 | $319.03 | $33817.18 |
| 2026-03-04 | GARG, PUSHKAL | EVP Chief R&D | Sale | 102 | $320.01 | $32641.02 |
| 2026-03-04 | FITZGERALD, KEVIN JOSEPH | CSO & EVP, Head of Research | Sale | 210 | $323.84 | $68006.40 |
| 2026-03-04 | FITZGERALD, KEVIN JOSEPH | CSO & EVP, Head of Research | Sale | 96 | $323.01 | $31008.96 |
| 2026-03-04 | FITZGERALD, KEVIN JOSEPH | CSO & EVP, Head of Research | Sale | 79 | $321.82 | $25423.78 |
| 2026-03-04 | FITZGERALD, KEVIN JOSEPH | CSO & EVP, Head of Research | Sale | 75 | $324.88 | $24366.00 |
| 2026-03-04 | FITZGERALD, KEVIN JOSEPH | CSO & EVP, Head of Research | Sale | 59 | $320.81 | $18927.79 |
| 2026-03-04 | FITZGERALD, KEVIN JOSEPH | CSO & EVP, Head of Research | Sale | 57 | $325.67 | $18563.19 |
| 2026-03-04 | FITZGERALD, KEVIN JOSEPH | CSO & EVP, Head of Research | Sale | 29 | $319.03 | $9251.87 |
| 2026-03-04 | FITZGERALD, KEVIN JOSEPH | CSO & EVP, Head of Research | Sale | 28 | $320.01 | $8960.28 |
| 2026-03-03 | GARG, PUSHKAL | EVP Chief R&D | Sale | 640 | $320.48 | $205107.20 |
| 2026-03-03 | GARG, PUSHKAL | EVP Chief R&D | Sale | 463 | $321.50 | $148854.50 |
| 2026-03-03 | GARG, PUSHKAL | EVP Chief R&D | Sale | 355 | $316.74 | $112442.70 |
| 2026-03-03 | GARG, PUSHKAL | EVP Chief R&D | Sale | 317 | $319.06 | $101142.02 |
| 2026-03-03 | FITZGERALD, KEVIN JOSEPH | CSO & EVP, Head of Research | Sale | 722 | $320.51 | $231408.22 |
| 2026-03-03 | FITZGERALD, KEVIN JOSEPH | CSO & EVP, Head of Research | Sale | 359 | $321.58 | $115447.22 |
| 2026-03-03 | FITZGERALD, KEVIN JOSEPH | CSO & EVP, Head of Research | Sale | 289 | $316.55 | $91482.95 |
| 2026-03-03 | FITZGERALD, KEVIN JOSEPH | CSO & EVP, Head of Research | Sale | 282 | $318.62 | $89850.84 |
| 2026-03-02 | TANGULER, TOLGA | EVP, Chief Commercial Officer | Buy | 10,480 | — | — |
| 2026-03-02 | TANGULER, TOLGA | EVP, Chief Commercial Officer | Buy | 4,769 | — | — |
Frequently asked questions
Are ALNY insiders buying or selling?
Over the transactions on record, ALNY insiders have been net sellers, with about $7.95M in stock sold across 77 sales, against 1 open-market purchase.
Does insider selling at ALNY mean the stock will fall?
Not by itself. Most executive selling is pre-scheduled through 10b5-1 plans filed months in advance, and insiders sell for diversification, taxes, and liquidity far more often than out of any view on the price. Insider buying is the stronger signal, especially when several insiders buy around the same time, because there is usually only one reason to put personal cash into the stock.
Which ALNY insiders are selling the most?
Recent selling is concentrated in a few names. GARG, PUSHKAL accounts for the largest share on record, with about $2.09M sold. Selling by one or two individuals matters less than broad selling across the whole leadership team, which is the pattern worth watching.