ALNY
Alnylam Pharmaceuticals Inc
NASDAQ: ALNY · HEALTHCARE · BIOTECHNOLOGY
$309.49
+2.76% today
Updated 2026-04-30
Market cap
$40.19B
P/E ratio
129.82
P/S ratio
10.82x
EPS (TTM)
$2.32
Dividend yield
—
52W range
$246 – $496
Volume
1.1M
Alnylam Pharmaceuticals Inc (ALNY) Financial statements
SEC filings — annual and quarterly data.
Income statement — annual
| Item | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $26.93M | $50.90M | $96.16M | $100.53M | $100.04M | $82.76M | $66.72M | $47.17M | $50.56M | $41.10M | $47.16M | $89.91M | $74.91M | $219.75M | $492.85M | $844.29M | $1.04B | $1.83B | $2.25B | $3.71B |
| Revenue growth (YoY) | — | +89.0% | +88.9% | +4.5% | -0.5% | -17.3% | -19.4% | -29.3% | +7.2% | -18.7% | +14.8% | +90.7% | -16.7% | +193.4% | +124.3% | +71.3% | +22.9% | +76.2% | +23.0% | +65.2% |
| Cost of revenue | $62.62M | $136.19M | $118.40M | $142.65M | $136.98M | $132.45M | $122.87M | $134.19M | $229.78M | $330.40M | $462.15M | $578.10M | $1.80M | $25.06M | $78.05M | $140.14M | $168.82M | $310.41M | $323.37M | $677.17M |
| Gross profit | $26.93M | $50.90M | $96.16M | $100.53M | $100.04M | $82.76M | $66.72M | $47.17M | $50.56M | $41.10M | $47.16M | $89.91M | $73.11M | $194.69M | $414.80M | $704.14M | $868.60M | $1.52B | $1.92B | $3.04B |
| Gross margin | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 97.6% | 88.6% | 84.2% | 83.4% | 83.7% | 83.0% | 85.6% | 81.8% |
| R&D | $49.80M | $120.69M | $96.88M | $108.73M | $106.38M | $99.30M | $86.57M | $112.96M | $190.25M | $276.50M | $382.39M | $390.63M | $505.42M | $655.11M | $654.82M | $792.16M | $883.01M | $1.00B | $1.13B | $1.32B |
| SG&A | $16.63M | $23.39M | $27.11M | $39.91M | $37.73M | $38.28M | $44.61M | $27.15M | $44.53M | $60.61M | $89.35M | $199.37M | $382.36M | $479.00M | $588.42M | $620.64M | $770.66M | $795.65M | $975.53M | $1.21B |
| Operating income | $-39.50M | $-93.18M | $-27.84M | $-48.11M | $-44.07M | $-54.82M | $-129.46M | $-92.94M | $-404.98M | $-296.01M | $-424.59M | $-500.09M | $-814.67M | $-939.43M | $-828.44M | $-708.65M | $-785.07M | $-282.18M | $-176.88M | $501.58M |
| Operating margin | -146.7% | -183.1% | -28.9% | -47.9% | -44.1% | -66.2% | -194.0% | -197.0% | -801.0% | -720.3% | -900.3% | -556.2% | -1087.6% | -427.5% | -168.1% | -83.9% | -75.7% | -15.4% | -7.9% | 13.5% |
| EBITDA | $-35.69M | $-75.06M | $-18.93M | $-41.02M | $-38.06M | $-49.69M | $-51.71M | $-82.71M | $-172.29M | $-276.96M | $-409.46M | $-486.72M | $-754.24M | $-885.06M | $-736.33M | $-661.56M | $-926.56M | $-258.24M | $-178.85M | $557.24M |
| EBITDA margin | -132.5% | -147.5% | -19.7% | -40.8% | -38.0% | -60.0% | -77.5% | -175.4% | -340.8% | -673.9% | -868.2% | -541.3% | -1006.9% | -402.8% | -149.4% | -78.4% | -89.3% | -14.1% | -8.0% | 15.0% |
| EBIT | $-39.50M | $-79.14M | $-24.66M | $-47.01M | $-43.00M | $-54.82M | $-60.75M | $-92.94M | $-184.21M | $-296.01M | $-424.59M | $-500.09M | $-760.67M | $-939.43M | $-771.10M | $-709.12M | $-971.02M | $-312.30M | $-235.52M | $501.58M |
| Interest expense | $1.03M | $1.08M | $872000.00 | $5.38M | $2.31M | $1.21M | $977000.00 | $1.07M | $2.56M | $5.86M | $8.31M | $12.24M | $29.26M | $108.55M | $84.50M | $143.02M | $155.97M | $121.22M | $141.86M | $252.63M |
| Income tax | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Effective tax rate | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
| Net income | $-34.61M | $-85.47M | $-26.25M | $-47.59M | $-43.52M | $-57.65M | $-106.01M | $-89.22M | $-360.39M | $-290.07M | $-410.11M | $-490.87M | $-761.50M | $-886.12M | $-858.28M | $-852.82M | $-1.13B | $-440.24M | $-278.16M | $313.75M |
| Net income growth (YoY) | — | -147.0% | +69.3% | -81.3% | +8.6% | -32.5% | -83.9% | +15.8% | -303.9% | +19.5% | -41.4% | -19.7% | -55.1% | -16.4% | +3.1% | +0.6% | -32.6% | +61.1% | +36.8% | +212.8% |
| Profit margin | -128.5% | -167.9% | -27.3% | -47.3% | -43.5% | -69.7% | -158.9% | -189.2% | -712.8% | -705.8% | -869.6% | -545.9% | -1016.6% | -403.2% | -174.1% | -101.0% | -109.0% | -24.1% | -12.4% | 8.4% |