WallStSmart
TWST

Twist Bioscience Corp

NASDAQ: TWST · HEALTHCARE · DIAGNOSTICS & RESEARCH

$56.21
-6.37% today

Updated 2026-06-05

Market cap
$4.74B
P/E ratio
P/S ratio
11.58x
EPS (TTM)
$-1.32
Dividend yield
52W range
$23 – $81
Volume
1.4M

Twist Bioscience Corp (TWST) Financial statements

SEC filings — annual and quarterly data.

Profit margin
-20.63%
Operating margin
-36.18%
ROE
-17.86%
ROA
-12.90%
Debt/equity
0.21x

Margin trends — annual

Gross margin Operating margin Profit margin
YearRevenueNet incomeGross marginOp. marginProfit margin
2016$2.27M$-44.09M-315.20%-1,924.02%-1,943.06%
2017$10.77M$-59.31M-123.09%-543.16%-550.85%
2018$25.43M$-71.24M-26.59%-277.50%-280.16%
2019$54.38M$-107.67M12.80%-200.15%-197.98%
2020$90.10M$-139.93M31.85%-155.47%-155.31%
2021$132.33M$-152.10M39.08%-115.41%-114.94%
2022$203.56M$-217.86M41.38%-122.33%-107.02%
2023$245.11M$-204.62M36.61%-88.60%-83.48%
2024$312.97M$-208.73M42.61%-70.56%-66.69%
2025$376.57M$-77.67M50.72%-36.18%-20.63%

Frequently asked questions

What is Twist Bioscience Corp's revenue?

Twist Bioscience Corp's trailing twelve-month revenue is $409.48M. Revenue is the top line the whole model builds on, and at this scale the question shifts from how fast it grows to whether margins hold as it compounds.

How profitable is TWST?

In its most recent fiscal year, TWST ran a gross margin of 50.72%, an operating margin of -36.18%, and a net margin of -20.63%. Margins this high mean most of each extra dollar of revenue drops through to profit, which is the signature of real pricing power.

How much free cash flow does TWST generate?

TWST produced $-75.63M in free cash flow in its most recent fiscal year. Free cash flow is what is left after running and reinvesting in the business, and it is the cash that actually funds buybacks, dividends, and a stronger balance sheet.

Is TWST's balance sheet healthy?

TWST holds $183.05M in cash and equivalents against — in long-term debt, on $472.96M of shareholder equity. That debt is best read against the cash flow the business throws off each year.