Omeros Corporation
NASDAQ: OMER · HEALTHCARE · BIOTECHNOLOGY
Updated 2026-06-03
Omeros Corporation (OMER) Stock Valuation Analysis
Fair value estimate, historical valuation range, and quality signals for OMER.
Current price exceeds what fundamentals support. Risk/reward skewed unfavorably.
OMER historical valuation range
Where current P/E sits in OMER's own 5Y range.
OMER intrinsic value (DCF)
DCF-based fair value estimate vs current market price.
Intrinsic value calculated using discounted cash flow (DCF) model based on projected free cash flows, discount rate, and terminal growth assumptions. A positive margin of safety indicates the current price is below estimated fair value, providing a cushion against estimation error.
OMER valuation signals
Quick-read green flags, caution flags, and risks based on current metrics.
P/E Ratio — History
Current: 8.59x
P/S Ratio — History
Current: 71.62x
Is OMER overvalued in 2026?
Omeros Corporation (OMER) currently trades at $14.38 per share with a market capitalization of $708,555,000.00. Based on our multi-factor framework, the stock appears richly valued with a Smart Value Score of 41/100. This score blends growth quality, financial health, and price attractiveness into a single institutional-grade read.
The stock trades at a P/E ratio of 8.6x. The PEG ratio of 0.81 suggests earnings growth is outpacing the multiple, a classic sign of undervaluation.
Our discounted cash flow model estimates OMER's intrinsic value at $25.16 per share, against the current market price of $14.38. This implies a margin of safety of +55.37%. A meaningful cushion exists against model error, making this a reasonable risk-adjusted entry.
Financial quality is a concern. The Piotroski F-Score of 3/9 flags weakening fundamentals that deserve closer scrutiny before the valuation case can be fully trusted.
Bottom line: OMER appears richly valued on our framework, with a Smart Value Score of 41/100. At current levels the risk/reward is skewed against the buyer. A materially lower price or significant operational improvement would be needed to change the picture.
Frequently asked questions
Is OMER overvalued?
OMER scores 41/100 on our Smart Value Score (Grade D), a weak overall profile. The DCF also shows a positive margin of safety, so price and fundamentals line up reasonably well.
What is OMER's fair value?
Our DCF model estimates OMER's intrinsic value at $25.16 per share, versus the current price of $14.38, a margin of safety of +55.37%. Fair value is the present value of the cash flows we project the business to produce, so a price below it means the market is pricing the stock below that conservative estimate.
What P/E ratio does OMER trade at?
OMER trades at a P/E of 8.6x on trailing twelve-month earnings. P/E is what you pay per dollar of profit.
Is OMER a buy based on valuation?
Our Smart Value rating for OMER is Sell, from a Smart Value Score of 41/100 that blends growth, quality, and valuation. The profile skews cautious, and a better price or clearer operating improvement would strengthen the case. This is research to inform your decision, not personalized financial advice.
How does OMER's valuation compare to its history?
There is not enough historical valuation data yet for a confident percentile read on OMER.
What is OMER's Smart Value Score?
OMER's Smart Value Score is 41/100. It is a proprietary WallStSmart metric blending growth quality, financial health, and valuation into a single 0-100 read, and scores above 75 are rare, signaling strong multi-factor alignment.