OMER
Omeros Corporation
NASDAQ: OMER · HEALTHCARE · BIOTECHNOLOGY
$17.88
+2.23% today
Updated 2026-10-28
Market cap
$1.22B
P/E ratio
13.28
P/S ratio
31.76x
EPS (TTM)
$1.27
Dividend yield
—
52W range
$6 – $21
Volume
1.4M
Omeros Corporation (OMER) Insider transactions
Net insider activity
Net buying (5,309,577 shares)
Buy transactions
80
Sell transactions
20
All transactions
| Date | Insider | Title | Type | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-07-22 | DEMOPULOS, GREGORY A MD | Director, Chairman, CEO & President | Buy | 1,000,000 | — | — |
| 2026-07-22 | CANCELMO, PETER B | VP, General Counsel | Buy | 105,000 | — | — |
| 2026-07-22 | BORGES, DAVID J. | VP, Finance & CAO | Buy | 105,000 | — | — |
| 2026-06-18 | SHAH, RAJIV | Director | Buy | 15,000 | — | — |
| 2026-06-18 | PERKINSON, DIANA T. | Director | Buy | 15,000 | — | — |
| 2026-06-18 | HOOD, LEROY E. MD PHD | Director | Buy | 15,000 | — | — |
| 2026-06-18 | HANISH, ARNOLD C | Director | Buy | 15,000 | — | — |
| 2026-06-18 | DEMOPULOS, PETER A MD | Director | Buy | 15,000 | — | — |
| 2026-06-18 | CABLE, THOMAS J. | Director | Buy | 15,000 | — | — |
| 2026-06-18 | BUMOL, THOMAS F. | Director | Buy | 15,000 | — | — |
| 2026-05-22 | CABLE, THOMAS J. | Director | Sale | 7,500 | — | — |
| 2026-05-22 | CABLE, THOMAS J. | Director | Buy | 7,500 | $10.84 | $81300.00 |
| 2026-02-18 | DEMOPULOS, GREGORY A MD | Director, Chairman, CEO & President | Sale | 400,000 | — | — |
| 2026-02-18 | DEMOPULOS, GREGORY A MD | Director, Chairman, CEO & President | Buy | 400,000 | $10.27 | $4.11M |
| 2026-02-18 | DEMOPULOS, GREGORY A MD | Director, Chairman, CEO & President | Sale | 357,678 | $11.93 | $4.27M |
| 2026-01-13 | BORGES, DAVID J. | VP, Finance & CAO | Sale | 30,000 | — | — |
| 2026-01-13 | BORGES, DAVID J. | VP, Finance & CAO | Sale | 30,000 | $12.31 | $369315.00 |
| 2026-01-12 | BORGES, DAVID J. | VP, Finance & CAO | Sale | 30,000 | $12.72 | $381600.00 |
| 2025-10-13 | DEMOPULOS, GREGORY A MD | Director, Chairman, CEO & President | Sale | 600,000 | — | — |
| 2025-10-13 | DEMOPULOS, GREGORY A MD | Director, Chairman, CEO & President | Buy | 300,000 | — | — |
| 2025-06-30 | DEMOPULOS, GREGORY A MD | Director, Chairman, CEO & President | Buy | 865,000 | — | — |
| 2025-06-30 | CANCELMO, PETER B | VP, General Counsel | Buy | 100,000 | — | — |
| 2025-06-30 | BORGES, DAVID J. | VP, Finance & CAO | Buy | 95,000 | — | — |
| 2025-06-27 | SHAH, RAJIV | Director | Buy | 15,000 | — | — |
| 2025-06-27 | PERKINSON, DIANA T. | Director | Buy | 15,000 | — | — |
| 2025-06-27 | HOOD, LEROY E. MD PHD | Director | Buy | 15,000 | — | — |
| 2025-06-27 | HANISH, ARNOLD C | Director | Buy | 15,000 | — | — |
| 2025-06-27 | DEMOPULOS, PETER A MD | Director | Buy | 15,000 | — | — |
| 2025-06-27 | CABLE, THOMAS J. | Director | Buy | 15,000 | — | — |
| 2025-06-27 | BUMOL, THOMAS F. | Director | Buy | 15,000 | — | — |
| 2024-06-06 | SHAH, RAJIV | Director | Buy | 15,000 | — | — |
| 2024-06-06 | PERKINSON, DIANA T. | Director | Buy | 15,000 | — | — |
| 2024-06-06 | HOOD, LEROY E. MD PHD | Director | Buy | 15,000 | — | — |
| 2024-06-06 | HANISH, ARNOLD C | Director | Buy | 15,000 | — | — |
| 2024-06-06 | DEMOPULOS, PETER A MD | Director | Buy | 15,000 | — | — |
| 2024-06-06 | CABLE, THOMAS J. | Director | Buy | 15,000 | — | — |
| 2024-06-06 | BUMOL, THOMAS F. | Director | Buy | 15,000 | — | — |
| 2024-04-25 | JACOBSEN, MICHAEL A | VP, Finance & CAO | Buy | 100,000 | — | — |
| 2024-04-25 | DEMOPULOS, GREGORY A MD | Director, Chairman, CEO & President | Buy | 725,000 | — | — |
| 2024-04-25 | CANCELMO, PETER B | VP, General Counsel | Buy | 100,000 | — | — |
| 2023-11-17 | DEMOPULOS, GREGORY A MD | Chairman, CEO & President | Buy | 15,000 | $1.68 | $25200.00 |
| 2023-11-15 | DEMOPULOS, PETER A MD | Director | Buy | 10,000 | $1.53 | $15300.00 |
| 2023-11-14 | DEMOPULOS, GREGORY A MD | Chairman, CEO & President | Buy | 25,000 | $1.44 | $36000.00 |
| 2023-11-13 | DEMOPULOS, GREGORY A MD | Chairman, CEO & President | Buy | 37,500 | $1.29 | $48375.00 |
| 2023-09-22 | JACOBSEN, MICHAEL A | VP, Finance & CAO | Buy | 100,000 | — | — |
| 2023-09-22 | DEMOPULOS, GREGORY A MD | Chairman, CEO & President | Buy | 715,000 | — | — |
| 2023-09-22 | CANCELMO, PETER B | VP, General Counsel | Buy | 100,000 | — | — |
| 2023-09-12 | BUMOL, THOMAS F. | Director | Buy | 10,000 | $3.31 | $33100.00 |
| 2023-06-23 | SHAH, RAJIV | Director | Buy | 15,000 | — | — |
| 2023-06-23 | HOOD, LEROY E. MD PHD | Director | Buy | 15,000 | — | — |
| 2023-06-23 | HANISH, ARNOLD C | Director | Buy | 15,000 | — | — |
| 2023-06-23 | DEMOPULOS, PETER A MD | Director | Buy | 15,000 | — | — |
| 2023-06-23 | CABLE, THOMAS J. | Director | Buy | 15,000 | — | — |
| 2023-06-23 | BUMOL, THOMAS F. | Director | Buy | 15,000 | — | — |
| 2023-05-22 | HANISH, ARNOLD C | Director | Sale | 5,000 | — | — |
| 2023-05-22 | HANISH, ARNOLD C | Director | Buy | 5,000 | $5.30 | $26500.00 |
| 2023-05-22 | CABLE, THOMAS J. | Director | Sale | 5,000 | — | — |
| 2023-05-22 | CABLE, THOMAS J. | Director | Sale | 5,000 | $6.53 | $32650.00 |
| 2023-05-12 | PERKINSON, DIANA T. | Director | Buy | 30,000 | — | — |
| 2022-09-21 | ZUMWALT, KURT | Director | Buy | 7,500 | — | — |
| 2022-09-21 | SHAH, RAJIV | Director | Buy | 7,500 | — | — |
| 2022-09-21 | JACOBSEN, MICHAEL A | VP FINANCE AND CAO | Buy | 85,000 | — | — |
| 2022-09-21 | HOOD, LEROY E. MD PHD | Director | Buy | 7,500 | — | — |
| 2022-09-21 | HANISH, ARNOLD C | Director | Buy | 7,500 | — | — |
| 2022-09-21 | DEMOPULOS, PETER A MD | Director | Buy | 7,500 | — | — |
| 2022-09-21 | DEMOPULOS, GREGORY A MD | Director, CHAIRMAN, CEO & PRESIDENT | Buy | 650,000 | — | — |
| 2022-09-21 | CANCELMO, PETER B | VP, GENERAL COUNSEL | Buy | 80,000 | — | — |
| 2022-09-21 | CABLE, THOMAS J. | Director | Buy | 7,500 | — | — |
| 2022-09-21 | BUMOL, THOMAS F. | Director | Buy | 7,500 | — | — |
| 2022-06-17 | ZUMWALT, KURT | Director | Buy | 7,500 | — | — |
| 2022-06-17 | SHAH, RAJIV | Director | Buy | 7,500 | — | — |
| 2022-06-17 | HOOD, LEROY E. MD PHD | Director | Buy | 7,500 | — | — |
| 2022-06-17 | HANISH, ARNOLD C | Director | Buy | 7,500 | — | — |
| 2022-06-17 | DEMOPULOS, PETER A MD | Director | Buy | 7,500 | — | — |
| 2022-06-17 | CABLE, THOMAS J. | Director | Buy | 7,500 | — | — |
| 2022-06-17 | BUMOL, THOMAS F. | Director | Buy | 7,500 | — | — |
| 2021-09-08 | HANISH, ARNOLD C | Director | Sale | 10,000 | — | — |
| 2021-09-08 | HANISH, ARNOLD C | Director | Buy | 10,000 | $9.44 | $94400.00 |
| 2021-07-02 | JACOBSEN, MICHAEL A | VP FINANCE AND CAO | Buy | 75,000 | — | — |
| 2021-07-02 | DEMOPULOS, GREGORY A MD | Director, CHAIRMAN, CEO & PRESIDENT | Buy | 550,000 | — | — |
| 2021-07-02 | CANCELMO, PETER B | VP, GEN. COUNSEL & CORP. SEC. | Buy | 75,000 | — | — |
| 2021-06-17 | DEMOPULOS, GREGORY A MD | Director, CHAIRMAN, CEO & PRESIDENT | Sale | 36,857 | — | — |
| 2021-06-17 | DEMOPULOS, GREGORY A MD | Director, CHAIRMAN, CEO & PRESIDENT | Sale | 36,857 | $14.90 | $549169.30 |
| 2021-06-15 | DEMOPULOS, GREGORY A MD | Director, CHAIRMAN, CEO & PRESIDENT | Sale | 36,856 | — | — |
| 2021-06-15 | DEMOPULOS, GREGORY A MD | Director, CHAIRMAN, CEO & PRESIDENT | Sale | 36,856 | $15.02 | $553577.12 |
| 2021-06-11 | ZUMWALT, KURT | Director | Buy | 7,500 | — | — |
| 2021-06-11 | SHAH, RAJIV | Director | Buy | 7,500 | — | — |
| 2021-06-11 | HOOD, LEROY E. MD PHD | Director | Buy | 7,500 | — | — |
| 2021-06-11 | HANISH, ARNOLD C | Director | Buy | 7,500 | — | — |
| 2021-06-11 | DEMOPULOS, PETER A MD | Director | Buy | 7,500 | — | — |
| 2021-06-11 | CABLE, THOMAS J. | Director | Buy | 7,500 | — | — |
| 2021-06-11 | BUMOL, THOMAS F. | Director | Buy | 7,500 | — | — |
| 2021-06-11 | ASPIRI, RAY | Director | Buy | 7,500 | — | — |
| 2021-05-20 | DEMOPULOS, GREGORY A MD | Director, CHAIRMAN, CEO & PRESIDENT | Sale | 36,856 | — | — |
| 2021-05-20 | DEMOPULOS, GREGORY A MD | Director, CHAIRMAN, CEO & PRESIDENT | Buy | 36,856 | $4.10 | $151109.60 |
| 2021-05-19 | DEMOPULOS, GREGORY A MD | Director, CHAIRMAN, CEO & PRESIDENT | Sale | 36,857 | — | — |
| 2021-05-19 | DEMOPULOS, GREGORY A MD | Director, CHAIRMAN, CEO & PRESIDENT | Buy | 36,857 | $4.10 | $151113.70 |
| 2021-04-08 | DEMOPULOS, GREGORY A MD | Director, CHAIRMAN, CEO & PRESIDENT | Sale | 35,206 | — | — |
| 2021-04-08 | DEMOPULOS, GREGORY A MD | Director, CHAIRMAN, CEO & PRESIDENT | Sale | 35,206 | $17.76 | $625258.56 |
| 2021-04-07 | DEMOPULOS, GREGORY A MD | Director, CHAIRMAN, CEO & PRESIDENT | Sale | 37,407 | — | — |
Frequently asked questions
Are OMER insiders buying or selling?
Over the transactions on record, OMER insiders have been net buyers, with about $6.78M in stock sold across 20 sales, against 11 open-market purchases.
Does insider selling at OMER mean the stock will fall?
Not by itself. Most executive selling is pre-scheduled through 10b5-1 plans filed months in advance, and insiders sell for diversification, taxes, and liquidity far more often than out of any view on the price. Insider buying is the stronger signal, especially when several insiders buy around the same time, because there is usually only one reason to put personal cash into the stock.
Which OMER insiders are selling the most?
Recent selling is concentrated in a few names. DEMOPULOS, GREGORY A MD accounts for the largest share on record, with about $6.00M sold. Selling by one or two individuals matters less than broad selling across the whole leadership team, which is the pattern worth watching.