Neurocrine Biosciences Inc
NASDAQ: NBIX · HEALTHCARE · DRUG MANUFACTURERS - SPECIALTY & GENERIC
Updated 2026-06-05
Neurocrine Biosciences Inc (NBIX) Stock Valuation Analysis
Fair value estimate, historical valuation range, and quality signals for NBIX.
Valued
Fundamentals support the current valuation. Strong combination of growth, quality, and price.
NBIX historical valuation range
Where current P/E sits in NBIX's own 5Y range.
NBIX intrinsic value (DCF)
DCF-based fair value estimate vs current market price.
Standard discounted cash flow models produce unreliable output for unprofitable or near-breakeven companies. Revenue-based multiples such as P/S and EV/Sales, combined with the historical valuation position above, give a more reliable read for this stock.
Intrinsic value calculated using discounted cash flow (DCF) model based on projected free cash flows, discount rate, and terminal growth assumptions. A positive margin of safety indicates the current price is below estimated fair value, providing a cushion against estimation error.
NBIX valuation signals
Quick-read green flags, caution flags, and risks based on current metrics.
P/E Ratio — History
Current: 24.58x
P/S Ratio — History
Current: 5.18x
Is NBIX overvalued in 2026?
Neurocrine Biosciences Inc (NBIX) currently trades at $150.59 per share with a market capitalization of $16,063,865,000.00. Based on our multi-factor framework, the stock looks attractively valued with a Smart Value Score of 81/100. This score blends growth quality, financial health, and price attractiveness into a single institutional-grade read.
The stock trades at a P/E ratio of 24.6x, below its 5-year median of 30.9x. The PEG ratio of 0.45 suggests earnings growth is outpacing the multiple, a classic sign of undervaluation.
Looking at its own history, NBIX is currently trading cheaper than 83% of the last 5Y on P/E. This places it in the 17th percentile of its historical range, a level that has historically coincided with attractive entry points.
A standard DCF model does not produce reliable output for NBIX under current conditions. For unprofitable or near-breakeven companies, revenue-based multiples such as EV/Sales and historical P/S percentile are more informative than intrinsic value calculations.
Financial quality is a concern. The Piotroski F-Score of 3/9 flags weakening fundamentals that deserve closer scrutiny before the valuation case can be fully trusted.
Bottom line: NBIX looks attractively valued on our framework, with a Smart Value Score of 81/100. The combination of reasonable price, healthy growth, and quality fundamentals makes it worth serious consideration.
Frequently asked questions
Is NBIX overvalued?
NBIX scores 81/100 on our Smart Value Score (Grade A), a strong overall profile. A standard DCF is unreliable here given the profitability profile, so valuation leans on revenue-based measures like EV/Sales and the P/S percentile below.
What is NBIX's fair value?
A standard DCF is unreliable for NBIX given its current profitability profile. Revenue-based approaches like EV/Sales or the historical P/S percentile are more informative for this stock.
What P/E ratio does NBIX trade at?
NBIX trades at a P/E of 24.6x on trailing twelve-month earnings, against a 5-year median of 30.9x. P/E is what you pay per dollar of profit, and sitting below its own median means the stock is cheaper than usual relative to its earnings.
Is NBIX a buy based on valuation?
Our Smart Value rating for NBIX is Strong Buy, from a Smart Value Score of 81/100 that blends growth, quality, and valuation. The rating leans on growth and financial strength, and valuation is usually the weakest leg for a name scoring this high. This is research to inform your decision, not personalized financial advice.
How does NBIX's valuation compare to its history?
On P/E, NBIX sits in the 17th percentile of its own 5Y range, historically cheap relative to where it has traded. A low percentile means today's multiple is near the bottom of its historical band.
What is NBIX's Smart Value Score?
NBIX's Smart Value Score is 81/100. It is a proprietary WallStSmart metric blending growth quality, financial health, and valuation into a single 0-100 read, and scores above 75 are rare, signaling strong multi-factor alignment.