MDGL
Madrigal Pharmaceuticals Inc
NASDAQ: MDGL · HEALTHCARE · BIOTECHNOLOGY
$431.00
-2.12% today
Updated 2026-10-28
Market cap
$10.39B
P/E ratio
—
P/S ratio
8.09x
EPS (TTM)
$-12.85
Dividend yield
—
52W range
$394 – $615
Volume
0.3M
Madrigal Pharmaceuticals Inc (MDGL) Insider transactions
Net insider activity
Net buying (35,234 shares)
Buy transactions
29
Sell transactions
71
All transactions
| Date | Insider | Title | Type | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-09-11 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 1,539 | $544.02 | $837252.94 |
| 2026-09-11 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 1,202 | $542.60 | $652209.05 |
| 2026-09-11 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 761 | $544.83 | $414616.16 |
| 2026-09-11 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 687 | $540.59 | $371382.38 |
| 2026-09-11 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 368 | $541.64 | $199324.37 |
| 2026-09-11 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 218 | $535.94 | $116835.68 |
| 2026-09-11 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 160 | $537.62 | $86018.80 |
| 2026-09-11 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 120 | $546.38 | $65565.20 |
| 2026-09-11 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 106 | $534.06 | $56610.68 |
| 2026-09-11 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 60 | $533.09 | $31985.48 |
| 2026-09-09 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 1,040 | $536.11 | $557556.79 |
| 2026-09-09 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 644 | $535.27 | $344715.10 |
| 2026-09-09 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 640 | $537.17 | $343791.23 |
| 2026-09-09 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 522 | $530.23 | $276780.63 |
| 2026-09-09 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 520 | $538.30 | $279914.49 |
| 2026-09-09 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 512 | $533.09 | $272943.72 |
| 2026-09-09 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 505 | $540.19 | $272796.40 |
| 2026-09-09 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 396 | $534.20 | $211541.77 |
| 2026-09-09 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 368 | $531.99 | $195772.21 |
| 2026-09-09 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 362 | $541.65 | $196078.68 |
| 2026-09-09 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 347 | $529.27 | $183655.68 |
| 2026-09-09 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 215 | $539.03 | $115891.04 |
| 2026-09-09 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 160 | $542.55 | $86807.60 |
| 2026-09-09 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 131 | $527.88 | $69152.06 |
| 2026-08-17 | KELLEY, SHANNON T | General Counsel | Sale | 664 | $514.97 | $341940.08 |
| 2026-08-15 | REED, JOHN C | Director | Buy | 1,078 | — | — |
| 2026-08-15 | REED, JOHN C | Director | Buy | 647 | — | — |
| 2026-07-20 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 680 | $547.70 | $372434.64 |
| 2026-07-20 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 545 | $544.71 | $296869.13 |
| 2026-07-20 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 280 | $555.05 | $155414.00 |
| 2026-07-20 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 275 | $545.71 | $150070.03 |
| 2026-07-20 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 269 | $547.08 | $147164.20 |
| 2026-07-20 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 153 | $550.01 | $84152.11 |
| 2026-07-20 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 140 | $542.75 | $75984.43 |
| 2026-07-20 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 110 | $543.79 | $59817.22 |
| 2026-07-20 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 47 | $548.87 | $25796.98 |
| 2026-07-20 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 1 | $550.72 | $550.72 |
| 2026-07-17 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 50,000 | — | — |
| 2026-07-17 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Buy | 50,000 | — | — |
| 2026-06-17 | TAUB, REBECCA | Director | Buy | 766 | — | — |
| 2026-06-17 | TAUB, REBECCA | Director | Buy | 454 | — | — |
| 2026-06-17 | LEVY, RICHARD S | Director | Buy | 766 | — | — |
| 2026-06-17 | LEVY, RICHARD S | Director | Buy | 454 | — | — |
| 2026-06-17 | FOUSE, JACQUALYN A | Director | Buy | 766 | — | — |
| 2026-06-17 | FOUSE, JACQUALYN A | Director | Buy | 454 | — | — |
| 2026-06-17 | DALY, JAMES M | Director | Buy | 766 | — | — |
| 2026-06-17 | DALY, JAMES M | Director | Buy | 454 | — | — |
| 2026-06-17 | BRENNAN, DANIEL J. | Director | Buy | 681 | — | — |
| 2026-06-17 | BRENNAN, DANIEL J. | Director | Buy | 404 | — | — |
| 2026-06-17 | BAKER, BROS. ADVISORS LP | Director | Buy | 1,532 | — | — |
| 2026-06-17 | BAKER, BROS. ADVISORS LP | Director | Buy | 908 | — | — |
| 2026-06-01 | SOERGEL, DAVID | Chief Medical Officer | Sale | 1,042 | $495.74 | $516561.08 |
| 2026-05-22 | LEVY, RICHARD S | Director | Sale | 1,497 | $517.59 | $774835.37 |
| 2026-05-22 | LEVY, RICHARD S | Director | Sale | 782 | $518.76 | $405668.76 |
| 2026-05-22 | LEVY, RICHARD S | Director | Sale | 723 | $516.87 | $373693.97 |
| 2026-05-22 | LEVY, RICHARD S | Director | Sale | 657 | $515.92 | $338960.69 |
| 2026-05-22 | LEVY, RICHARD S | Director | Sale | 610 | $511.40 | $311951.99 |
| 2026-05-22 | LEVY, RICHARD S | Director | Sale | 439 | $512.50 | $224988.47 |
| 2026-05-22 | LEVY, RICHARD S | Director | Sale | 343 | $514.67 | $176531.50 |
| 2026-05-22 | LEVY, RICHARD S | Director | Sale | 320 | $508.24 | $162637.44 |
| 2026-05-22 | LEVY, RICHARD S | Director | Sale | 151 | $510.36 | $77064.04 |
| 2026-05-22 | LEVY, RICHARD S | Director | Sale | 80 | $519.98 | $41598.40 |
| 2026-05-22 | LEVY, RICHARD S | Director | Sale | 40 | $506.68 | $20267.00 |
| 2026-05-18 | SOERGEL, DAVID | Chief Medical Officer | Sale | 844 | $515.90 | $435419.60 |
| 2026-03-06 | TAUB, REBECCA | Director | Sale | 491 | $431.94 | $212082.54 |
| 2026-03-06 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 1,663 | $431.94 | $718316.22 |
| 2026-03-06 | KELLEY, SHANNON T | General Counsel | Sale | 360 | $431.94 | $155498.40 |
| 2026-03-06 | HUNTSMAN, CAROLE | Chief Commercial Officer | Sale | 419 | $431.94 | $180982.86 |
| 2026-03-06 | DIER, MARDI | EVP and CFO | Sale | 646 | $431.94 | $279033.24 |
| 2026-03-06 | DIER, MARDI | EVP and CFO | Sale | 420 | $426.86 | $179282.80 |
| 2026-03-06 | DIER, MARDI | EVP and CFO | Sale | 160 | $429.00 | $68639.20 |
| 2026-03-06 | DIER, MARDI | EVP and CFO | Sale | 120 | $430.90 | $51708.40 |
| 2026-03-06 | DIER, MARDI | EVP and CFO | Sale | 116 | $432.56 | $50176.48 |
| 2026-03-06 | DIER, MARDI | EVP and CFO | Sale | 80 | $427.85 | $34227.60 |
| 2026-03-06 | DIER, MARDI | EVP and CFO | Sale | 40 | $429.58 | $17183.20 |
| 2026-03-04 | SOERGEL, DAVID | Chief Medical Officer | Buy | 5,467 | — | — |
| 2026-03-04 | SOERGEL, DAVID | Chief Medical Officer | Buy | 4,374 | — | — |
| 2026-03-04 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Buy | 18,743 | — | — |
| 2026-03-04 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Buy | 14,995 | — | — |
| 2026-03-04 | KELLEY, SHANNON T | General Counsel | Buy | 5,022 | — | — |
| 2026-03-04 | KELLEY, SHANNON T | General Counsel | Buy | 4,017 | — | — |
| 2026-03-04 | HUNTSMAN, CAROLE | Chief Commercial Officer | Buy | 4,986 | — | — |
| 2026-03-04 | HUNTSMAN, CAROLE | Chief Commercial Officer | Buy | 3,989 | — | — |
| 2026-03-04 | DIER, MARDI | EVP and CFO | Buy | 6,519 | — | — |
| 2026-03-04 | DIER, MARDI | EVP and CFO | Buy | 5,215 | — | — |
| 2026-03-02 | DIER, MARDI | EVP and CFO | Sale | 1,183 | $427.21 | $505389.43 |
| 2026-02-23 | LEVY, RICHARD S | Director | Sale | 2,500 | — | — |
| 2026-02-23 | LEVY, RICHARD S | Director | Buy | 2,500 | $7.36 | $18400.00 |
| 2026-01-26 | TAUB, REBECCA | Director | Sale | 647 | $492.42 | $318595.74 |
| 2026-01-26 | SIBOLD, WILLIAM JOHN | Director, President and CEO | Sale | 1,577 | $492.42 | $776546.34 |
| 2026-01-26 | LEVY, RICHARD S | Director | Sale | 4,000 | — | — |
| 2026-01-26 | LEVY, RICHARD S | Director | Buy | 4,000 | $16.46 | $65840.00 |
| 2026-01-26 | HUNTSMAN, CAROLE | Chief Commercial Officer | Sale | 570 | $494.59 | $281916.30 |
| 2026-01-26 | HUNTSMAN, CAROLE | Chief Commercial Officer | Sale | 340 | $492.42 | $167422.80 |
| 2026-01-20 | TAUB, REBECCA | Director | Sale | 2,238 | $490.77 | $1.10M |
| 2026-01-20 | KELLEY, SHANNON T | General Counsel | Sale | 429 | $501.40 | $215100.60 |
| 2026-01-20 | KELLEY, SHANNON T | General Counsel | Sale | 263 | $490.77 | $129072.51 |
| 2026-01-15 | THAKKAR, RITA | Chief Accounting Officer | Buy | 1,826 | — | — |
| 2026-01-15 | THAKKAR, RITA | Chief Accounting Officer | Buy | 2,398 | — | — |
| 2026-01-09 | TAUB, REBECCA | Director | Sale | 18,410 | — | — |
Frequently asked questions
Are MDGL insiders buying or selling?
Over the transactions on record, MDGL insiders have been net sellers, with about $17.25M in stock sold across 71 sales, against 2 open-market purchases.
Does insider selling at MDGL mean the stock will fall?
Not by itself. Most executive selling is pre-scheduled through 10b5-1 plans filed months in advance, and insiders sell for diversification, taxes, and liquidity far more often than out of any view on the price. Insider buying is the stronger signal, especially when several insiders buy around the same time, because there is usually only one reason to put personal cash into the stock.
Which MDGL insiders are selling the most?
Recent selling is concentrated in a few names. SIBOLD, WILLIAM JOHN accounts for the largest share on record, with about $9.10M sold. Selling by one or two individuals matters less than broad selling across the whole leadership team, which is the pattern worth watching.