Ligand Pharmaceuticals Incorporated
NASDAQ: LGND · HEALTHCARE · BIOTECHNOLOGY
Updated 2026-04-29
Ligand Pharmaceuticals Incorporated (LGND) Stock Valuation Analysis
Fair value estimate, historical valuation range, and quality signals for LGND.
Valued
Valuation reasonably reflects current fundamentals. Limited margin of safety at these levels.
LGND historical valuation range
Where current P/E sits in LGND's own 5Y range.
LGND intrinsic value (DCF)
DCF-based fair value estimate vs current market price.
Intrinsic value calculated using discounted cash flow (DCF) model based on projected free cash flows, discount rate, and terminal growth assumptions. A positive margin of safety indicates the current price is below estimated fair value, providing a cushion against estimation error.
LGND valuation signals
Quick-read green flags, caution flags, and risks based on current metrics.
P/E Ratio — History
Current: 36.74x
P/S Ratio — History
Current: 10.17x
Is LGND overvalued in 2026?
Ligand Pharmaceuticals Incorporated (LGND) currently trades at $224.86 per share with a market capitalization of $2,727,418,000.00. Based on our multi-factor framework, the stock trades at a fair valuation with a Smart Value Score of 74/100. This score blends growth quality, financial health, and price attractiveness into a single institutional-grade read.
The stock trades at a P/E ratio of 36.7x, below its 5-year median of 37.7x. The PEG ratio of 1.53 points to a price that reasonably reflects expected earnings growth.
Looking at its own history, LGND is currently trading cheaper than 58% of the last 5Y on P/E. This places it in the 42th percentile of its historical range, a reasonable but unremarkable position.
Our discounted cash flow model estimates LGND's intrinsic value at $272.89 per share, against the current market price of $224.86. This implies a margin of safety of +31.86%. A meaningful cushion exists against model error, making this a reasonable risk-adjusted entry.
The Piotroski F-Score of 4/9 puts financial quality in a middling range, neither a standout strength nor an obvious red flag.
Bottom line: LGND trades at a fair valuation on our framework, with a Smart Value Score of 74/100. The valuation is defensible but offers no obvious bargain. Patience or a better entry price may reward disciplined buyers.
Frequently asked questions
Is LGND overvalued in 2026?
Based on a Smart Value Score of 74/100, LGND is fairly valued. Price reasonably reflects current fundamentals with limited cushion in either direction.
What is LGND's fair value?
Our DCF model estimates LGND's intrinsic value at $272.89 per share, versus the current price of $224.86. This produces a margin of safety of +31.86%.
What P/E ratio does LGND trade at?
LGND trades at a P/E of 36.7x on trailing twelve-month earnings, compared to its 5-year median of 37.7x.
Is LGND a buy based on valuation?
WallStSmart does not issue buy or sell recommendations. Our Smart Value Score of 74/100 reflects the combined read on growth, quality, and price. The profile is balanced. Best suited for investors with an existing thesis.
How does LGND's valuation compare to its history?
On P/E, LGND currently sits in the 42th percentile of its own 5Y range. That is below its long-run median relative to where it has traded over the period.
What is LGND's Smart Value Score?
LGND's Smart Value Score is 74/100. The Smart Value Score is a proprietary WallStSmart metric blending growth quality, financial health, and valuation attractiveness into a single 0-100 read. Scores above 75 are rare and indicate strong multi-factor alignment.