WallStSmart
ARWR

Arrowhead Pharmaceuticals Inc

NASDAQ: ARWR · HEALTHCARE · BIOTECHNOLOGY

$77.74
-2.75% today

Updated 2026-06-05

Market cap
$10.50B
P/E ratio
P/S ratio
16.88x
EPS (TTM)
$-2.27
Dividend yield
52W range
$14 – $82
Volume
1.7M

Arrowhead Pharmaceuticals Inc (ARWR) Financial statements

SEC filings — annual and quarterly data.

Profit margin
-0.20%
Operating margin
11.86%
ROE
-49.01%
ROA
-7.22%
Debt/equity
2.24x

Margin trends — annual

Gross margin Operating margin Profit margin
YearRevenueNet incomeGross marginOp. marginProfit margin
2006$595458.00$-19.00M-1,135.71%-3,439.94%-3,190.35%
2007$1.21M$-29.93M-874.84%-3,141.43%-2,477.70%
2008$1.30M$-27.09M-1,039.80%-2,685.89%-2,078.65%
2009$3.76M$-19.31M-139.91%-520.47%-513.77%
2010$620097.00$-5.77M-698.68%-1,419.46%-931.15%
2011$296139.00$-3.13M9.51%-3,319.48%-1,056.56%
2012$146875.00$-21.13M-1,090.79%-14,358.61%-14,383.61%
2013$290266.00$-31.14M100.00%-8,471.29%-10,729.22%
2014$175000.00$-58.63M100.00%-30,443.59%-33,502.97%
2015$382000.00$-91.94M100.00%-25,124.08%-24,068.29%
2016$158333.00$-81.72M100.00%-51,627.09%-51,614.63%
2017$31.41M$-34.38M100.00%-117.79%-109.46%
2018$16.14M$-54.45M100.00%-346.52%-337.32%
2019$168.80M$67.97M100.00%36.25%40.27%
2020$87.99M$-84.55M100.00%-105.87%-96.09%
2021$138.29M$-140.85M100.00%-107.77%-101.85%
2022$243.23M$-176.49M100.00%-73.39%-72.56%
2023$240.74M$-205.28M94.81%-85.16%-85.27%
2024$3.55M$-599.49M-423.66%-16,927.06%-16,882.37%
2025$829.45M$-1.63M100.00%11.86%-0.20%

Frequently asked questions

What is Arrowhead Pharmaceuticals Inc's revenue?

Arrowhead Pharmaceuticals Inc's trailing twelve-month revenue is $622.01M. Revenue is the top line the whole model builds on, and at this scale the question shifts from how fast it grows to whether margins hold as it compounds.

How profitable is ARWR?

In its most recent fiscal year, ARWR ran a gross margin of 100.00%, an operating margin of 11.86%, and a net margin of -0.20%. Margins this high mean most of each extra dollar of revenue drops through to profit, which is the signature of real pricing power.

How much free cash flow does ARWR generate?

ARWR produced $156.89M in free cash flow in its most recent fiscal year. Free cash flow is what is left after running and reinvesting in the business, and it is the cash that actually funds buybacks, dividends, and a stronger balance sheet.

Is ARWR's balance sheet healthy?

ARWR holds $226.55M in cash and equivalents against $214.88M in long-term debt, on $466.05M of shareholder equity. Cash on hand exceeds long-term debt, so the balance sheet adds little financial risk to the thesis.