WallStSmart

Merck & Company Inc (MRK)vsProtagonist Therapeutics Inc (PTGX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Merck & Company Inc generates 88700% more annual revenue ($65.77B vs $74.06M). MRK leads profitability with a 13.6% profit margin vs -154.9%. MRK earns a higher WallStSmart Score of 50/100 (D+).

MRK

Hold

50

out of 100

Grade: D+

Growth: 3.3Profit: 8.0Value: 2.7Quality: 5.0
Piotroski: 3/9Altman Z: 2.30

PTGX

Hold

38

out of 100

Grade: F

Growth: 10.0Profit: 2.0Value: 5.0Quality: 8.5
Piotroski: 3/9Altman Z: 6.08
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

MRKSignificantly Overvalued (-49.3%)

Margin of Safety

-49.3%

Fair Value

$80.88

Current Price

$120.79

$39.91 premium

UndervaluedFair: $80.88Overvalued

Intrinsic value data unavailable for PTGX.

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

MRK3 strengths · Avg: 9.3/10
Market CapQuality
$285.64B10/10

Mega-cap, among the largest globally

Operating MarginProfitability
38.6%10/10

Strong operational efficiency at 38.6%

Free Cash FlowQuality
$2.93B8/10

Generating 2.9B in free cash flow

PTGX4 strengths · Avg: 10.0/10
Revenue GrowthGrowth
99.0%10/10

Revenue surging 99.0% year-over-year

EPS GrowthGrowth
351.3%10/10

Earnings expanding 351.3% YoY

Debt/EquityHealth
0.0110/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
6.0810/10

Safe zone — low bankruptcy risk

Areas to Watch

MRK4 concerns · Avg: 3.5/10
P/E RatioValuation
32.6x4/10

Premium valuation, high expectations priced in

Revenue GrowthGrowth
4.9%4/10

4.9% revenue growth

Debt/EquityHealth
1.073/10

Elevated debt levels

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

PTGX4 concerns · Avg: 2.8/10
Price/BookValuation
9.5x4/10

Trading at 9.5x book value

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Return on EquityProfitability
-17.5%2/10

ROE of -17.5% — below average capital efficiency

Free Cash FlowQuality
$-49.16M2/10

Negative free cash flow — burning cash

Comparative Analysis Report

WallStSmart Research

Bull Case : MRK

The strongest argument for MRK centers on Market Cap, Operating Margin, Free Cash Flow.

Bull Case : PTGX

The strongest argument for PTGX centers on Revenue Growth, EPS Growth, Debt/Equity. Revenue growth of 99.0% demonstrates continued momentum.

Bear Case : MRK

The primary concerns for MRK are P/E Ratio, Revenue Growth, Debt/Equity.

Bear Case : PTGX

The primary concerns for PTGX are Price/Book, Piotroski F-Score, Return on Equity.

Key Dynamics to Monitor

MRK profiles as a value stock while PTGX is a hypergrowth play — different risk/reward profiles.

PTGX carries more volatility with a beta of 1.88 — expect wider price swings.

PTGX is growing revenue faster at 99.0% — sustainability is the question.

MRK generates stronger free cash flow (2.9B), providing more financial flexibility.

Bottom Line

MRK scores higher overall (50/100 vs 38/100). Both earn "Hold" and "Hold" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Merck & Company Inc

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

Merck & Co. is an American multinational pharmaceutical company headquartered in Kenilworth, New Jersey. It is named after the Merck family, which set up Merck Group in Germany in 1668.

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Protagonist Therapeutics Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Protagonist Therapeutics, Inc., a clinical-stage biopharmaceutical company, discovers and develops peptide-based therapeutic drugs to address unmet medical needs. The company is headquartered in Newark, California.

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