WallStSmart

Johnson & Johnson (JNJ)vsProtagonist Therapeutics Inc (PTGX)

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Smart Verdict

WallStSmart Research — data-driven comparison

Johnson & Johnson generates 34628% more annual revenue ($97.93B vs $281.99M). PTGX leads profitability with a 29.4% profit margin vs 21.5%. JNJ trades at a lower P/E of 30.9x. PTGX earns a higher WallStSmart Score of 63/100 (C+).

JNJ

Buy

59

out of 100

Grade: C

Growth: 4.7Profit: 8.5Value: 2.7Quality: 6.0
Piotroski: 4/9Altman Z: 2.64

PTGX

Buy

63

out of 100

Grade: C+

Growth: 10.0Profit: 7.0Value: 4.0Quality: 8.5
Piotroski: 3/9Altman Z: 6.08
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

JNJSignificantly Overvalued (-88.9%)

Margin of Safety

-88.9%

Fair Value

$140.57

Current Price

$266.38

$125.81 premium

UndervaluedFair: $140.57Overvalued

Intrinsic value data unavailable for PTGX.

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

JNJ5 strengths · Avg: 8.8/10
Market CapQuality
$640.02B10/10

Mega-cap, among the largest globally

Return on EquityProfitability
24.8%9/10

Every $100 of equity generates 25 in profit

Profit MarginProfitability
21.5%9/10

Keeps 22 of every $100 in revenue as profit

Operating MarginProfitability
29.2%8/10

Strong operational efficiency at 29.2%

Free Cash FlowQuality
$3.39B8/10

Generating 3.4B in free cash flow

PTGX6 strengths · Avg: 9.8/10
Operating MarginProfitability
74.4%10/10

Strong operational efficiency at 74.4%

Revenue GrowthGrowth
3749.0%10/10

Revenue surging 3749.0% year-over-year

EPS GrowthGrowth
351.3%10/10

Earnings expanding 351.3% YoY

Debt/EquityHealth
0.0110/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
6.0810/10

Safe zone — low bankruptcy risk

Profit MarginProfitability
29.4%9/10

Keeps 29 of every $100 in revenue as profit

Areas to Watch

JNJ3 concerns · Avg: 2.7/10
P/E RatioValuation
30.9x4/10

Premium valuation, high expectations priced in

PEG RatioValuation
2.792/10

Expensive relative to growth rate

EPS GrowthGrowth
-0.9%2/10

Earnings declined 0.9%

PTGX4 concerns · Avg: 2.8/10
Price/BookValuation
11.4x4/10

Trading at 11.4x book value

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

P/E RatioValuation
140.9x2/10

Premium valuation, high expectations priced in

Return on EquityProfitability
-17.5%2/10

ROE of -17.5% — below average capital efficiency

Comparative Analysis Report

WallStSmart Research

Bull Case : JNJ

The strongest argument for JNJ centers on Market Cap, Return on Equity, Profit Margin. Profitability is solid with margins at 21.5% and operating margin at 29.2%.

Bull Case : PTGX

The strongest argument for PTGX centers on Operating Margin, Revenue Growth, EPS Growth. Profitability is solid with margins at 29.4% and operating margin at 74.4%. Revenue growth of 3749.0% demonstrates continued momentum.

Bear Case : JNJ

The primary concerns for JNJ are P/E Ratio, PEG Ratio, EPS Growth.

Bear Case : PTGX

The primary concerns for PTGX are Price/Book, Piotroski F-Score, P/E Ratio. A P/E of 140.9x leaves little room for execution misses.

Key Dynamics to Monitor

JNJ profiles as a mature stock while PTGX is a growth play — different risk/reward profiles.

PTGX carries more volatility with a beta of 1.79 — expect wider price swings.

PTGX is growing revenue faster at 3749.0% — sustainability is the question.

JNJ generates stronger free cash flow (3.4B), providing more financial flexibility.

Bottom Line

PTGX scores higher overall (63/100 vs 59/100), backed by strong 29.4% margins and 3749.0% revenue growth. Both earn "Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Johnson & Johnson

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

Johnson & Johnson (J&J) is an American multinational corporation founded in 1886 that develops medical devices, pharmaceuticals, and consumer packaged goods. Its common stock is a component of the Dow Jones Industrial Average and the company is ranked No. 36 on the 2021 Fortune 500 list of the largest United States corporations by total revenue. Johnson & Johnson is one of the world's most valuable companies, and is one of only two U.S.-based companies that has a prime credit rating of AAA, higher than that of the United States government.

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Protagonist Therapeutics Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Protagonist Therapeutics, Inc., a clinical-stage biopharmaceutical company, discovers and develops peptide-based therapeutic drugs to address unmet medical needs. The company is headquartered in Newark, California.

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