WallStSmart

Insmed Inc (INSM)vsKrystal Biotech Inc (KRYS)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Insmed Inc generates 56% more annual revenue ($606.42M vs $389.13M). KRYS leads profitability with a 52.6% profit margin vs -2.1%. KRYS earns a higher WallStSmart Score of 57/100 (C).

INSM

Hold

39

out of 100

Grade: F

Growth: 6.0Profit: 2.0Value: 6.7Quality: 6.3
Piotroski: 6/9Altman Z: -3.77

KRYS

Buy

57

out of 100

Grade: C

Growth: 6.3Profit: 9.0Value: 5.7Quality: 9.0
Piotroski: 4/9Altman Z: 7.95
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

Intrinsic value data unavailable for INSM.

KRYSSignificantly Overvalued (-57.2%)

Margin of Safety

-57.2%

Fair Value

$173.46

Current Price

$254.95

$81.49 premium

UndervaluedFair: $173.46Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

INSM0 strengths · Avg: 0/10

No standout strengths identified

KRYS5 strengths · Avg: 9.6/10
Profit MarginProfitability
52.6%10/10

Keeps 53 of every $100 in revenue as profit

Operating MarginProfitability
41.3%10/10

Strong operational efficiency at 41.3%

Debt/EquityHealth
0.0110/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
7.9510/10

Safe zone — low bankruptcy risk

Revenue GrowthGrowth
17.5%8/10

17.5% revenue growth

Areas to Watch

INSM4 concerns · Avg: 3.0/10
Revenue GrowthGrowth
1.5%4/10

1.5% revenue growth

EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Price/BookValuation
43.0x2/10

Trading at 43.0x book value

Return on EquityProfitability
-2.5%2/10

ROE of -2.5% — below average capital efficiency

KRYS1 concerns · Avg: 4.0/10
P/E RatioValuation
36.1x4/10

Premium valuation, high expectations priced in

Comparative Analysis Report

WallStSmart Research

Bull Case : INSM

PEG of 1.09 suggests the stock is reasonably priced for its growth.

Bull Case : KRYS

The strongest argument for KRYS centers on Profit Margin, Operating Margin, Debt/Equity. Profitability is solid with margins at 52.6% and operating margin at 41.3%. Revenue growth of 17.5% demonstrates continued momentum.

Bear Case : INSM

The primary concerns for INSM are Revenue Growth, EPS Growth, Price/Book.

Bear Case : KRYS

The primary concerns for KRYS are P/E Ratio.

Key Dynamics to Monitor

INSM profiles as a turnaround stock while KRYS is a growth play — different risk/reward profiles.

INSM carries more volatility with a beta of 1.17 — expect wider price swings.

KRYS is growing revenue faster at 17.5% — sustainability is the question.

KRYS generates stronger free cash flow (75M), providing more financial flexibility.

Bottom Line

KRYS scores higher overall (57/100 vs 39/100), backed by strong 52.6% margins and 17.5% revenue growth. Both earn "Buy" and "Hold" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Insmed Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Insmed Incorporated, a biopharmaceutical company, develops and markets therapies for patients with rare and serious diseases. The company is headquartered in Bridgewater, New Jersey.

Krystal Biotech Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Krystal Biotech, Inc., a clinical-stage biotechnology company, is dedicated to the field of redosable gene therapy to treat serious rare diseases in the United States. The company is headquartered in Pittsburgh, Pennsylvania.

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