WallStSmart

argenx NV ADR (ARGX)vsKrystal Biotech Inc (KRYS)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

argenx NV ADR generates 1107% more annual revenue ($5.32B vs $440.48M). KRYS leads profitability with a 54.8% profit margin vs 32.3%. ARGX trades at a lower P/E of 37.9x. ARGX earns a higher WallStSmart Score of 73/100 (B).

ARGX

Strong Buy

73

out of 100

Grade: B

Growth: 10.0Profit: 9.5Value: 6.7Quality: 8.5
Piotroski: 3/9Altman Z: 4.92

KRYS

Buy

65

out of 100

Grade: C+

Growth: 7.7Profit: 9.0Value: 4.7Quality: 9.0
Piotroski: 4/9Altman Z: 8.02
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ARGXUndervalued (+64.8%)

Margin of Safety

+64.8%

Fair Value

$2372.23

Current Price

$963.79

$1408.44 discount

UndervaluedFair: $2372.23Overvalued

Intrinsic value data unavailable for KRYS.

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ARGX6 strengths · Avg: 10.0/10
Return on EquityProfitability
30.8%10/10

Every $100 of equity generates 31 in profit

Profit MarginProfitability
32.3%10/10

Keeps 32 of every $100 in revenue as profit

Operating MarginProfitability
32.0%10/10

Strong operational efficiency at 32.0%

Revenue GrowthGrowth
59.3%10/10

Revenue surging 59.3% year-over-year

EPS GrowthGrowth
95.2%10/10

Earnings expanding 95.2% YoY

Debt/EquityHealth
0.0110/10

Conservative balance sheet, low leverage

KRYS6 strengths · Avg: 9.3/10
Profit MarginProfitability
54.8%10/10

Keeps 55 of every $100 in revenue as profit

Operating MarginProfitability
49.0%10/10

Strong operational efficiency at 49.0%

Debt/EquityHealth
0.0110/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
8.0210/10

Safe zone — low bankruptcy risk

Revenue GrowthGrowth
24.1%8/10

Revenue surging 24.1% year-over-year

EPS GrowthGrowth
38.8%8/10

Earnings expanding 38.8% YoY

Areas to Watch

ARGX3 concerns · Avg: 3.0/10
P/E RatioValuation
37.9x4/10

Premium valuation, high expectations priced in

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Price/BookValuation
179.1x2/10

Trading at 179.1x book value

KRYS1 concerns · Avg: 2.0/10
P/E RatioValuation
41.9x2/10

Premium valuation, high expectations priced in

Comparative Analysis Report

WallStSmart Research

Bull Case : ARGX

The strongest argument for ARGX centers on Return on Equity, Profit Margin, Operating Margin. Profitability is solid with margins at 32.3% and operating margin at 32.0%. Revenue growth of 59.3% demonstrates continued momentum.

Bull Case : KRYS

The strongest argument for KRYS centers on Profit Margin, Operating Margin, Debt/Equity. Profitability is solid with margins at 54.8% and operating margin at 49.0%. Revenue growth of 24.1% demonstrates continued momentum.

Bear Case : ARGX

The primary concerns for ARGX are P/E Ratio, Piotroski F-Score, Price/Book.

Bear Case : KRYS

The primary concerns for KRYS are P/E Ratio. A P/E of 41.9x leaves little room for execution misses.

Key Dynamics to Monitor

KRYS carries more volatility with a beta of 0.54 — expect wider price swings.

ARGX is growing revenue faster at 59.3% — sustainability is the question.

ARGX generates stronger free cash flow (749M), providing more financial flexibility.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

ARGX scores higher overall (73/100 vs 65/100), backed by strong 32.3% margins and 59.3% revenue growth. Both earn "Strong Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

argenx NV ADR

HEALTHCARE · BIOTECHNOLOGY · USA

argenx SE, a clinical-phase biotechnology company, focuses on the development of antibody-based therapies for the treatment of autoimmune diseases, hematology and cancer. The company is headquartered in Breda, the Netherlands.

Krystal Biotech Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Krystal Biotech, Inc., a clinical-stage biotechnology company, is dedicated to the field of redosable gene therapy to treat serious rare diseases in the United States. The company is headquartered in Pittsburgh, Pennsylvania.

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