WallStSmart

Alnylam Pharmaceuticals Inc (ALNY)vsKrystal Biotech Inc (KRYS)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Alnylam Pharmaceuticals Inc generates 927% more annual revenue ($4.29B vs $417.30M). KRYS leads profitability with a 53.9% profit margin vs 12.6%. KRYS trades at a lower P/E of 39.7x. KRYS earns a higher WallStSmart Score of 65/100 (C+).

ALNY

Strong Buy

65

out of 100

Grade: B-

Growth: 8.0Profit: 8.0Value: 6.7Quality: 5.0

KRYS

Buy

65

out of 100

Grade: C+

Growth: 8.3Profit: 9.0Value: 4.7Quality: 9.0
Piotroski: 4/9Altman Z: 7.95
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ALNYUndervalued (+86.6%)

Margin of Safety

+86.6%

Fair Value

$2410.60

Current Price

$295.05

$2115.55 discount

UndervaluedFair: $2410.60Overvalued

Intrinsic value data unavailable for KRYS.

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ALNY4 strengths · Avg: 9.0/10
Return on EquityProfitability
90.4%10/10

Every $100 of equity generates 90 in profit

Revenue GrowthGrowth
96.4%10/10

Revenue surging 96.4% year-over-year

PEG RatioValuation
0.518/10

Growing faster than its price suggests

Operating MarginProfitability
23.0%8/10

Strong operational efficiency at 23.0%

KRYS6 strengths · Avg: 10.0/10
Profit MarginProfitability
53.9%10/10

Keeps 54 of every $100 in revenue as profit

Operating MarginProfitability
46.1%10/10

Strong operational efficiency at 46.1%

Revenue GrowthGrowth
31.9%10/10

Revenue surging 31.9% year-over-year

EPS GrowthGrowth
52.5%10/10

Earnings expanding 52.5% YoY

Debt/EquityHealth
0.0110/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
7.9510/10

Safe zone — low bankruptcy risk

Areas to Watch

ALNY3 concerns · Avg: 2.7/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

P/E RatioValuation
74.2x2/10

Premium valuation, high expectations priced in

Price/BookValuation
36.6x2/10

Trading at 36.6x book value

KRYS1 concerns · Avg: 4.0/10
P/E RatioValuation
39.7x4/10

Premium valuation, high expectations priced in

Comparative Analysis Report

WallStSmart Research

Bull Case : ALNY

The strongest argument for ALNY centers on Return on Equity, Revenue Growth, PEG Ratio. Revenue growth of 96.4% demonstrates continued momentum. PEG of 0.51 suggests the stock is reasonably priced for its growth.

Bull Case : KRYS

The strongest argument for KRYS centers on Profit Margin, Operating Margin, Revenue Growth. Profitability is solid with margins at 53.9% and operating margin at 46.1%. Revenue growth of 31.9% demonstrates continued momentum.

Bear Case : ALNY

The primary concerns for ALNY are EPS Growth, P/E Ratio, Price/Book. A P/E of 74.2x leaves little room for execution misses.

Bear Case : KRYS

The primary concerns for KRYS are P/E Ratio.

Key Dynamics to Monitor

KRYS carries more volatility with a beta of 0.49 — expect wider price swings.

ALNY is growing revenue faster at 96.4% — sustainability is the question.

KRYS generates stronger free cash flow (73M), providing more financial flexibility.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

ALNY scores higher overall (65/100 vs 65/100) and 96.4% revenue growth. Both earn "Strong Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

Krystal Biotech Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Krystal Biotech, Inc., a clinical-stage biotechnology company, is dedicated to the field of redosable gene therapy to treat serious rare diseases in the United States. The company is headquartered in Pittsburgh, Pennsylvania.

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