WallStSmart

Applied Therapeutics Inc (APLT)vsAstraZeneca PLC (AZN)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 5873800% more annual revenue ($58.74B vs $1.00M). AZN leads profitability with a 17.4% profit margin vs 0.0%. AZN earns a higher WallStSmart Score of 64/100 (C+).

APLT

Avoid

27

out of 100

Grade: F

Growth: 6.3Profit: 2.5Value: 6.7Quality: 4.5
Piotroski: 3/9Altman Z: -11.31

AZN

Buy

64

out of 100

Grade: C+

Growth: 6.7Profit: 8.0Value: 5.3Quality: 5.0
Piotroski: 6/9Altman Z: 1.48
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

APLTUndervalued (+63.2%)

Margin of Safety

+63.2%

Fair Value

$0.28

Current Price

$0.10

$0.18 discount

UndervaluedFair: $0.28Overvalued
AZNUndervalued (+4.1%)

Margin of Safety

+4.1%

Fair Value

$214.51

Current Price

$187.37

$27.14 discount

UndervaluedFair: $214.51Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

APLT2 strengths · Avg: 10.0/10
Revenue GrowthGrowth
720.0%10/10

Revenue surging 720.0% year-over-year

Debt/EquityHealth
-4.4610/10

Conservative balance sheet, low leverage

AZN5 strengths · Avg: 9.0/10
Market CapQuality
$287.11B10/10

Mega-cap, among the largest globally

EPS GrowthGrowth
53.9%10/10

Earnings expanding 53.9% YoY

Return on EquityProfitability
22.8%9/10

Every $100 of equity generates 23 in profit

Operating MarginProfitability
21.6%8/10

Strong operational efficiency at 21.6%

Free Cash FlowQuality
$1.38B8/10

Generating 1.4B in free cash flow

Areas to Watch

APLT4 concerns · Avg: 3.3/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$14.86M3/10

Smaller company, higher risk/reward

Profit MarginProfitability
0.0%3/10

0.0% margin — thin

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

AZN4 concerns · Avg: 3.5/10
PEG RatioValuation
1.544/10

Expensive relative to growth rate

P/E RatioValuation
27.9x4/10

Moderate valuation

Revenue GrowthGrowth
4.1%4/10

4.1% revenue growth

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

Comparative Analysis Report

WallStSmart Research

Bull Case : APLT

The strongest argument for APLT centers on Revenue Growth, Debt/Equity. Revenue growth of 720.0% demonstrates continued momentum.

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, EPS Growth, Return on Equity. Profitability is solid with margins at 17.4% and operating margin at 21.6%.

Bear Case : APLT

The primary concerns for APLT are EPS Growth, Market Cap, Profit Margin.

Bear Case : AZN

The primary concerns for AZN are PEG Ratio, P/E Ratio, Revenue Growth.

Key Dynamics to Monitor

APLT profiles as a hypergrowth stock while AZN is a value play — different risk/reward profiles.

APLT carries more volatility with a beta of 2.08 — expect wider price swings.

APLT is growing revenue faster at 720.0% — sustainability is the question.

AZN generates stronger free cash flow (1.4B), providing more financial flexibility.

Bottom Line

AZN scores higher overall (64/100 vs 27/100), backed by strong 17.4% margins. APLT offers better value entry with a 63.2% margin of safety. Both earn "Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Applied Therapeutics Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Applied Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops novel products to combat cardiovascular disease, galactosemia, and diabetes complications. The company is headquartered in New York, New York.

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AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

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