WallStSmart

argenx NV ADR (ARGX)vsAstraZeneca PLC (AZN)

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Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 1287% more annual revenue ($58.74B vs $4.24B). ARGX leads profitability with a 30.5% profit margin vs 17.4%. ARGX appears more attractively valued with a PEG of 1.11. AZN earns a higher WallStSmart Score of 64/100 (C+).

ARGX

Buy

61

out of 100

Grade: C+

Growth: 7.3Profit: 9.0Value: 4.0Quality: 6.0
Piotroski: 3/9

AZN

Buy

64

out of 100

Grade: C+

Growth: 6.7Profit: 8.0Value: 6.7Quality: 5.0
Piotroski: 6/9Altman Z: 1.48
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ARGXSignificantly Overvalued (-527.1%)

Margin of Safety

-527.1%

Fair Value

$133.08

Current Price

$691.40

$558.32 premium

UndervaluedFair: $133.08Overvalued
AZNUndervalued (+32.8%)

Margin of Safety

+32.8%

Fair Value

$306.07

Current Price

$193.92

$112.15 discount

UndervaluedFair: $306.07Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ARGX4 strengths · Avg: 9.3/10
Profit MarginProfitability
30.5%10/10

Keeps 31 of every $100 in revenue as profit

Revenue GrowthGrowth
73.0%10/10

Revenue surging 73.0% year-over-year

Return on EquityProfitability
20.2%9/10

Every $100 of equity generates 20 in profit

Operating MarginProfitability
27.4%8/10

Strong operational efficiency at 27.4%

AZN5 strengths · Avg: 9.0/10
Market CapQuality
$292.10B10/10

Mega-cap, among the largest globally

EPS GrowthGrowth
53.9%10/10

Earnings expanding 53.9% YoY

Return on EquityProfitability
22.8%9/10

Every $100 of equity generates 23 in profit

Operating MarginProfitability
21.6%8/10

Strong operational efficiency at 21.6%

Free Cash FlowQuality
$1.38B8/10

Generating 1.4B in free cash flow

Areas to Watch

ARGX3 concerns · Avg: 3.0/10
P/E RatioValuation
35.3x4/10

Premium valuation, high expectations priced in

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

EPS GrowthGrowth
-31.9%2/10

Earnings declined 31.9%

AZN4 concerns · Avg: 3.5/10
PEG RatioValuation
1.554/10

Expensive relative to growth rate

P/E RatioValuation
28.8x4/10

Moderate valuation

Revenue GrowthGrowth
4.1%4/10

4.1% revenue growth

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

Comparative Analysis Report

WallStSmart Research

Bull Case : ARGX

The strongest argument for ARGX centers on Profit Margin, Revenue Growth, Return on Equity. Profitability is solid with margins at 30.5% and operating margin at 27.4%. Revenue growth of 73.0% demonstrates continued momentum.

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, EPS Growth, Return on Equity. Profitability is solid with margins at 17.4% and operating margin at 21.6%.

Bear Case : ARGX

The primary concerns for ARGX are P/E Ratio, Piotroski F-Score, EPS Growth.

Bear Case : AZN

The primary concerns for AZN are PEG Ratio, P/E Ratio, Revenue Growth.

Key Dynamics to Monitor

ARGX profiles as a growth stock while AZN is a value play — different risk/reward profiles.

AZN carries more volatility with a beta of 0.23 — expect wider price swings.

ARGX is growing revenue faster at 73.0% — sustainability is the question.

AZN generates stronger free cash flow (1.4B), providing more financial flexibility.

Bottom Line

AZN scores higher overall (64/100 vs 61/100), backed by strong 17.4% margins. Both earn "Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

argenx NV ADR

HEALTHCARE · BIOTECHNOLOGY · USA

argenx SE, a clinical-phase biotechnology company, focuses on the development of antibody-based therapies for the treatment of autoimmune diseases, hematology and cancer. The company is headquartered in Breda, the Netherlands.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

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