WallStSmart

Applied Therapeutics Inc (APLT)vsargenx NV ADR (ARGX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

argenx NV ADR generates 531447% more annual revenue ($5.32B vs $1.00M). ARGX leads profitability with a 32.3% profit margin vs 0.0%. ARGX earns a higher WallStSmart Score of 73/100 (B).

APLT

Avoid

27

out of 100

Grade: F

Growth: 6.3Profit: 2.5Value: 6.7Quality: 4.5
Piotroski: 3/9Altman Z: -11.31

ARGX

Strong Buy

73

out of 100

Grade: B

Growth: 10.0Profit: 9.5Value: 6.7Quality: 8.5
Piotroski: 3/9Altman Z: 4.92
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

APLTUndervalued (+57.1%)

Margin of Safety

+57.1%

Fair Value

$0.24

Current Price

$0.10

$0.14 discount

UndervaluedFair: $0.24Overvalued
ARGXUndervalued (+65.6%)

Margin of Safety

+65.6%

Fair Value

$2427.69

Current Price

$872.58

$1555.11 discount

UndervaluedFair: $2427.69Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

APLT2 strengths · Avg: 10.0/10
Revenue GrowthGrowth
720.0%10/10

Revenue surging 720.0% year-over-year

Debt/EquityHealth
-4.4610/10

Conservative balance sheet, low leverage

ARGX6 strengths · Avg: 10.0/10
Return on EquityProfitability
30.8%10/10

Every $100 of equity generates 31 in profit

Profit MarginProfitability
32.3%10/10

Keeps 32 of every $100 in revenue as profit

Operating MarginProfitability
32.0%10/10

Strong operational efficiency at 32.0%

Revenue GrowthGrowth
59.3%10/10

Revenue surging 59.3% year-over-year

EPS GrowthGrowth
95.2%10/10

Earnings expanding 95.2% YoY

Debt/EquityHealth
0.0110/10

Conservative balance sheet, low leverage

Areas to Watch

APLT4 concerns · Avg: 3.3/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$14.86M3/10

Smaller company, higher risk/reward

Profit MarginProfitability
0.0%3/10

0.0% margin — thin

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

ARGX3 concerns · Avg: 3.0/10
P/E RatioValuation
33.2x4/10

Premium valuation, high expectations priced in

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Price/BookValuation
184.5x2/10

Trading at 184.5x book value

Comparative Analysis Report

WallStSmart Research

Bull Case : APLT

The strongest argument for APLT centers on Revenue Growth, Debt/Equity. Revenue growth of 720.0% demonstrates continued momentum.

Bull Case : ARGX

The strongest argument for ARGX centers on Return on Equity, Profit Margin, Operating Margin. Profitability is solid with margins at 32.3% and operating margin at 32.0%. Revenue growth of 59.3% demonstrates continued momentum.

Bear Case : APLT

The primary concerns for APLT are EPS Growth, Market Cap, Profit Margin.

Bear Case : ARGX

The primary concerns for ARGX are P/E Ratio, Piotroski F-Score, Price/Book.

Key Dynamics to Monitor

APLT profiles as a hypergrowth stock while ARGX is a growth play — different risk/reward profiles.

APLT carries more volatility with a beta of 2.08 — expect wider price swings.

APLT is growing revenue faster at 720.0% — sustainability is the question.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

ARGX scores higher overall (73/100 vs 27/100), backed by strong 32.3% margins and 59.3% revenue growth. APLT offers better value entry with a 57.1% margin of safety. Both earn "Strong Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Applied Therapeutics Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Applied Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops novel products to combat cardiovascular disease, galactosemia, and diabetes complications. The company is headquartered in New York, New York.

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argenx NV ADR

HEALTHCARE · BIOTECHNOLOGY · USA

argenx SE, a clinical-phase biotechnology company, focuses on the development of antibody-based therapies for the treatment of autoimmune diseases, hematology and cancer. The company is headquartered in Breda, the Netherlands.

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