WallStSmart

Alnylam Pharmaceuticals Inc (ALNY)vsTG Therapeutics Inc (TGTX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Alnylam Pharmaceuticals Inc generates 503% more annual revenue ($3.71B vs $616.29M). TGTX leads profitability with a 72.6% profit margin vs 8.5%. TGTX trades at a lower P/E of 10.9x. TGTX earns a higher WallStSmart Score of 63/100 (C+).

ALNY

Hold

49

out of 100

Grade: D+

Growth: 8.0Profit: 7.0Value: 3.0Quality: 5.0

TGTX

Buy

63

out of 100

Grade: C+

Growth: 5.7Profit: 9.5Value: 7.3Quality: 5.8
Piotroski: 4/9Altman Z: -0.51
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ALNYSignificantly Overvalued (-1925.6%)

Margin of Safety

-1925.6%

Fair Value

$15.91

Current Price

$328.70

$312.79 premium

UndervaluedFair: $15.91Overvalued
TGTXSignificantly Overvalued (-53.0%)

Margin of Safety

-53.0%

Fair Value

$18.84

Current Price

$31.82

$12.98 premium

UndervaluedFair: $18.84Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ALNY2 strengths · Avg: 10.0/10
Return on EquityProfitability
73.3%10/10

Every $100 of equity generates 73 in profit

Revenue GrowthGrowth
84.9%10/10

Revenue surging 84.9% year-over-year

TGTX5 strengths · Avg: 9.6/10
P/E RatioValuation
10.9x10/10

Attractively priced relative to earnings

Return on EquityProfitability
102.8%10/10

Every $100 of equity generates 103 in profit

Profit MarginProfitability
72.6%10/10

Keeps 73 of every $100 in revenue as profit

Revenue GrowthGrowth
78.0%10/10

Revenue surging 78.0% year-over-year

Operating MarginProfitability
26.2%8/10

Strong operational efficiency at 26.2%

Areas to Watch

ALNY3 concerns · Avg: 2.7/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

P/E RatioValuation
131.7x2/10

Premium valuation, high expectations priced in

Price/BookValuation
55.2x2/10

Trading at 55.2x book value

TGTX3 concerns · Avg: 2.7/10
PEG RatioValuation
1.614/10

Expensive relative to growth rate

EPS GrowthGrowth
-6.1%2/10

Earnings declined 6.1%

Altman Z-ScoreHealth
-0.512/10

Distress zone — elevated risk

Comparative Analysis Report

WallStSmart Research

Bull Case : ALNY

The strongest argument for ALNY centers on Return on Equity, Revenue Growth. Revenue growth of 84.9% demonstrates continued momentum.

Bull Case : TGTX

The strongest argument for TGTX centers on P/E Ratio, Return on Equity, Profit Margin. Profitability is solid with margins at 72.6% and operating margin at 26.2%. Revenue growth of 78.0% demonstrates continued momentum.

Bear Case : ALNY

The primary concerns for ALNY are EPS Growth, P/E Ratio, Price/Book. A P/E of 131.7x leaves little room for execution misses.

Bear Case : TGTX

The primary concerns for TGTX are PEG Ratio, EPS Growth, Altman Z-Score.

Key Dynamics to Monitor

ALNY profiles as a hypergrowth stock while TGTX is a growth play — different risk/reward profiles.

TGTX carries more volatility with a beta of 1.86 — expect wider price swings.

ALNY is growing revenue faster at 84.9% — sustainability is the question.

ALNY generates stronger free cash flow (140M), providing more financial flexibility.

Bottom Line

TGTX scores higher overall (63/100 vs 49/100), backed by strong 72.6% margins and 78.0% revenue growth. Both earn "Buy" and "Hold" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

TG Therapeutics Inc

HEALTHCARE · BIOTECHNOLOGY · USA

TG Therapeutics, Inc., a commercial-stage biopharmaceutical company, focuses on the acquisition, development, and commercialization of novel treatments for B-cell malignancies and autoimmune diseases. The company is headquartered in New York, New York.

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