WallStSmart

Alnylam Pharmaceuticals Inc (ALNY)vsargenx NV ADR (ARGX)

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Smart Verdict

WallStSmart Research — data-driven comparison

argenx NV ADR generates 23% more annual revenue ($5.92B vs $4.80B). ARGX leads profitability with a 31.7% profit margin vs 16.1%. ALNY appears more attractively valued with a PEG of 0.29. ARGX earns a higher WallStSmart Score of 73/100 (B).

ALNY

Strong Buy

68

out of 100

Grade: B-

Growth: 8.0Profit: 8.5Value: 8.0Quality: 6.0
Piotroski: 4/9Altman Z: -0.02

ARGX

Strong Buy

73

out of 100

Grade: B

Growth: 10.0Profit: 9.5Value: 6.7Quality: 8.5
Piotroski: 3/9Altman Z: 4.92
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ALNYUndervalued (+87.3%)

Margin of Safety

+87.3%

Fair Value

$2546.59

Current Price

$174.00

$2372.59 discount

UndervaluedFair: $2546.59Overvalued
ARGXUndervalued (+67.5%)

Margin of Safety

+67.5%

Fair Value

$2566.94

Current Price

$897.85

$1669.09 discount

UndervaluedFair: $2566.94Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ALNY3 strengths · Avg: 10.0/10
PEG RatioValuation
0.2910/10

Growing faster than its price suggests

Return on EquityProfitability
59.7%10/10

Every $100 of equity generates 60 in profit

Revenue GrowthGrowth
66.9%10/10

Revenue surging 66.9% year-over-year

ARGX6 strengths · Avg: 10.0/10
Return on EquityProfitability
30.8%10/10

Every $100 of equity generates 31 in profit

Profit MarginProfitability
31.7%10/10

Keeps 32 of every $100 in revenue as profit

Operating MarginProfitability
36.3%10/10

Strong operational efficiency at 36.3%

Revenue GrowthGrowth
52.1%10/10

Revenue surging 52.1% year-over-year

EPS GrowthGrowth
50.6%10/10

Earnings expanding 50.6% YoY

Debt/EquityHealth
0.0110/10

Conservative balance sheet, low leverage

Areas to Watch

ALNY4 concerns · Avg: 3.5/10
P/E RatioValuation
39.2x4/10

Premium valuation, high expectations priced in

Price/BookValuation
17.2x4/10

Trading at 17.2x book value

EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Altman Z-ScoreHealth
-0.022/10

Distress zone — elevated risk

ARGX3 concerns · Avg: 3.0/10
P/E RatioValuation
30.3x4/10

Premium valuation, high expectations priced in

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Price/BookValuation
166.9x2/10

Trading at 166.9x book value

Comparative Analysis Report

WallStSmart Research

Bull Case : ALNY

The strongest argument for ALNY centers on PEG Ratio, Return on Equity, Revenue Growth. Profitability is solid with margins at 16.1% and operating margin at 17.9%. Revenue growth of 66.9% demonstrates continued momentum.

Bull Case : ARGX

The strongest argument for ARGX centers on Return on Equity, Profit Margin, Operating Margin. Profitability is solid with margins at 31.7% and operating margin at 36.3%. Revenue growth of 52.1% demonstrates continued momentum.

Bear Case : ALNY

The primary concerns for ALNY are P/E Ratio, Price/Book, EPS Growth.

Bear Case : ARGX

The primary concerns for ARGX are P/E Ratio, Piotroski F-Score, Price/Book.

Key Dynamics to Monitor

ALNY carries more volatility with a beta of 0.27 — expect wider price swings.

ALNY is growing revenue faster at 66.9% — sustainability is the question.

ARGX generates stronger free cash flow (749M), providing more financial flexibility.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

ARGX scores higher overall (73/100 vs 68/100), backed by strong 31.7% margins and 52.1% revenue growth. ALNY offers better value entry with a 87.3% margin of safety. Both earn "Strong Buy" and "Strong Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

argenx NV ADR

HEALTHCARE · BIOTECHNOLOGY · USA

argenx SE, a clinical-phase biotechnology company, focuses on the development of antibody-based therapies for the treatment of autoimmune diseases, hematology and cancer. The company is headquartered in Breda, the Netherlands.

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