WallStSmart
VRTX

Vertex Pharmaceuticals Inc

NASDAQ: VRTX · HEALTHCARE · BIOTECHNOLOGY

$444.93
-0.03% today

Updated 2026-06-12

Market cap
$107.89B
P/E ratio
25.26
P/S ratio
8.83x
EPS (TTM)
$16.83
Dividend yield
52W range
$363 – $508
Volume
1.2M

Vertex Pharmaceuticals Inc (VRTX) Financial statements

SEC filings — annual and quarterly data.

Profit margin
32.74%
Operating margin
39.43%
ROE
22.41%
ROA
12.10%
Debt/equity
0.10x

Margin trends — annual

Gross margin Operating margin Profit margin
YearRevenueNet incomeGross marginOp. marginProfit margin
2006$216.36M$-206.89M94.38%-105.86%-95.63%
2007$199.01M$-391.28M93.01%-210.94%-196.61%
2008$175.50M$-459.85M91.06%-263.65%-262.02%
2009$102.05M$-641.58M86.08%-601.10%-628.70%
2010$143.37M$-754.63M91.12%-485.51%-526.35%
2011$1.41B$29.57M94.29%8.07%2.10%
2012$1.53B$-107.03M81.67%0.15%-7.01%
2013$1.21B$-445.03M89.25%-74.54%-36.72%
2014$580.41M$-738.55M89.49%-119.30%-127.25%
2015$1.03B$-558.12M87.84%-45.40%-54.06%
2016$1.70B$-112.05M87.64%0.58%-6.58%
2017$2.49B$263.48M88.95%4.95%10.59%
2018$3.05B$2.10B86.56%20.84%68.80%
2019$4.16B$1.18B86.84%28.77%28.27%
2020$6.21B$2.71B88.14%46.03%43.70%
2021$7.57B$2.34B88.06%36.73%30.92%
2022$8.93B$3.32B87.90%48.23%37.20%
2023$9.87B$3.62B87.21%38.83%36.68%
2024$11.02B$-535.60M86.11%-2.11%-4.86%
2025$12.07B$3.95B85.03%39.43%32.74%

Frequently asked questions

What is Vertex Pharmaceuticals Inc's revenue?

Vertex Pharmaceuticals Inc's trailing twelve-month revenue is $12.22B. Revenue is the top line the whole model builds on, and at this scale the question shifts from how fast it grows to whether margins hold as it compounds.

How profitable is VRTX?

In its most recent fiscal year, VRTX ran a gross margin of 85.03%, an operating margin of 39.43%, and a net margin of 32.74%. Margins this high mean most of each extra dollar of revenue drops through to profit, which is the signature of real pricing power.

How much free cash flow does VRTX generate?

VRTX produced $3.19B in free cash flow in its most recent fiscal year. Free cash flow is what is left after running and reinvesting in the business, and it is the cash that actually funds buybacks, dividends, and a stronger balance sheet.

Is VRTX's balance sheet healthy?

VRTX holds $5.09B in cash and equivalents against — in long-term debt, on $18.67B of shareholder equity. That debt is best read against the cash flow the business throws off each year.