WallStSmart
VNDA

Vanda Pharmaceuticals Inc

NASDAQ: VNDA · HEALTHCARE · BIOTECHNOLOGY

$5.05
+1.41% today

Updated 2026-09-25

Market cap
$310.17M
P/E ratio
—
P/S ratio
1.44x
EPS (TTM)
$-4.64
Dividend yield
—
52W range
$4 – $10
Volume
0.9M

Vanda Pharmaceuticals Inc (VNDA) Stock Valuation Analysis

Fair value estimate, historical valuation range, and quality signals for VNDA.

WallStSmart Verdict
Overvalued

Current price exceeds what fundamentals support. Risk/reward skewed unfavorably.

Smart Value Score: 35 / 100
P/E (TTM)
—
Not meaningful for this profile
PEG
2.23
Elevated vs growth
Margin of Safety
+82.90%
Fair value $35.79 vs $5.05
EV / EBITDA
0.8x

VNDA historical valuation range

Where current P/E sits in VNDA's own 5Y range.

NOW
20.6x
5Y Low
25.1x
25th
31.7x
Median
59.8x
75th
84.4x
5Y High
VNDA is trading cheaper than 100% of the last 5Y.
0th percentile · Historically cheap

VNDA intrinsic value (DCF)

DCF-based fair value estimate vs current market price.

Current price
$5.05
Market value
Intrinsic value
$35.79
DCF estimate
Margin of safety
+82.90%
+608.7% upside to fair value

Intrinsic value calculated using discounted cash flow (DCF) model based on projected free cash flows, discount rate, and terminal growth assumptions. A positive margin of safety indicates the current price is below estimated fair value, providing a cushion against estimation error.

VNDA valuation signals

Quick-read green flags, caution flags, and risks based on current metrics.

✕
PEG above 2.0
PEG of 2.23 suggests price is running ahead of growth rate. Caution warranted.
✓
Strong margin of safety
Current price 82.9% below DCF intrinsic value estimate. Meaningful downside cushion.
✕
Weak financial quality
Piotroski F-Score of 2/9 suggests deteriorating fundamentals. Valuation requires closer scrutiny.

P/E Ratio — History

P/S Ratio — History

Current: 1.44x

Is VNDA overvalued in 2026?

Vanda Pharmaceuticals Inc (VNDA) currently trades at $5.05 per share with a market capitalization of $310,174,000.00. Based on our multi-factor framework, the stock appears richly valued with a Smart Value Score of 35/100. This score blends growth quality, financial health, and price attractiveness into a single institutional-grade read.

VNDA currently has no meaningful P/E ratio, which typically signals that the company is unprofitable, near breakeven, or emerging from a loss-making period. With a P/S ratio of 1.4x, the market is valuing the company primarily on its revenue rather than its earnings.

Looking at its own history, VNDA is currently trading cheaper than 100% of the last 5Y on P/E. This places it in the 0th percentile of its historical range, a level that has historically coincided with attractive entry points.

Our discounted cash flow model estimates VNDA's intrinsic value at $35.79 per share, against the current market price of $5.05. This implies a margin of safety of +82.90%. A meaningful cushion exists against model error, making this a reasonable risk-adjusted entry.

Financial quality is a concern. The Piotroski F-Score of 2/9 flags weakening fundamentals that deserve closer scrutiny before the valuation case can be fully trusted.

Bottom line: VNDA appears richly valued on our framework, with a Smart Value Score of 35/100. At current levels the risk/reward is skewed against the buyer. A materially lower price or significant operational improvement would be needed to change the picture.

Frequently asked questions

Is VNDA overvalued?

VNDA scores 35/100 on our Smart Value Score (Grade D), a weak overall profile. The DCF also shows a positive margin of safety, so price and fundamentals line up reasonably well.

What is VNDA's fair value?

Our DCF model estimates VNDA's intrinsic value at $35.79 per share, versus the current price of $5.05, a margin of safety of +82.90%. Fair value is the present value of the cash flows we project the business to produce, so a price below it means the market is pricing the stock below that conservative estimate.

What P/E ratio does VNDA trade at?

VNDA does not have a meaningful P/E right now, usually a sign of unprofitability or an earnings transition. For unprofitable growth names, price-to-sales is the more useful gauge.

Is VNDA a buy based on valuation?

Our Smart Value rating for VNDA is Sell, from a Smart Value Score of 35/100 that blends growth, quality, and valuation. The profile skews cautious, and a better price or clearer operating improvement would strengthen the case. This is research to inform your decision, not personalized financial advice.

How does VNDA's valuation compare to its history?

On P/E, VNDA sits in the 0th percentile of its own 5Y range, historically cheap relative to where it has traded. A low percentile means today's multiple is near the bottom of its historical band.

What is VNDA's Smart Value Score?

VNDA's Smart Value Score is 35/100. It is a proprietary WallStSmart metric blending growth quality, financial health, and valuation into a single 0-100 read, and scores above 75 are rare, signaling strong multi-factor alignment.