WallStSmart
SYBX

Synlogic Inc

NASDAQ: SYBX · HEALTHCARE · BIOTECHNOLOGY

$0.64
+0.00% today

Updated 2026-06-04

Market cap
$7.72M
P/E ratio
P/S ratio
936.86x
EPS (TTM)
$-0.06
Dividend yield
52W range
$1 – $2
Volume
0.0M

Synlogic Inc (SYBX) Financial statements

SEC filings — annual and quarterly data.

Income statement — annual

Item201120122013201420152016201720182019202020212022202320242025
Revenue$0.00$444000.00$2.44M$2.52M$2.22M$545000.00$1.75M$1.18M$3.37M$8000.00$0.00
Revenue growth (YoY)+450.5%+3.1%-11.7%-75.5%+221.8%-32.7%+185.7%-99.8%-100.0%
Cost of revenue$37000.00$54000.00$159000.00$40.96M$14.90M$5.67M$5.29M$1.29M
Gross profit$-37000.00$-54000.00$285000.00$2.44M$2.52M$2.22M$545000.00$1.75M$1.18M$3.37M$8000.00
Gross margin64.2%100.0%100.0%100.0%100.0%100.0%100.0%100.0%100.0%
R&D$980000.00$2.74M$4.39M$10.54M$18.95M$13.93M$30.34M$38.03M$41.91M$47.47M$47.13M$52.04M$43.97M$9.15M$43000.00
SG&A$1.56M$2.38M$3.37M$6.08M$8.12M$12.93M$15.72M$14.73M$13.54M$15.39M$16.55M$14.56M$6.63M$3.49M
Operating income$-2.48M$-4.30M$-6.78M$-15.83M$-25.03M$-26.62M$-40.82M$-51.23M$-54.41M$-60.47M$-60.77M$-67.42M$-55.16M$-40.95M$-4.01M
Operating margin-5995.0%-1670.4%-2032.9%-2446.4%-11094.7%-3464.4%-5713.5%-1636.3%-511875.0%
EBITDA$-2.45M$-3.27M$-6.74M$-15.80M$-24.97M$-24.70M$-38.51M$-48.81M$-51.71M$-57.83M$-58.32M$-63.63M$-55.31M$-22.06M$-3.53M
EBITDA margin-5562.4%-1575.9%-1936.9%-2325.0%-10611.0%-3325.1%-5391.9%-1640.7%-275737.5%
EBIT$-2.48M$-3.30M$-6.78M$-15.83M$-25.03M$-25.39M$-40.82M$-51.23M$-54.41M$-60.47M$-60.77M$-66.14M$-57.27M$-23.35M
Interest expense$399000.00$355000.00$0.00$0.00$44000.00$0.00$57000.00$43000.00$21000.00$6000.00$2000.00$2000.00$1000.00$0.00
Income tax$355000.00$-54000.00$4.06M$-2.31M$2.84M$-2.70M$-2.64M$-2.44M$-1.27M$14000.00$5000.00
Effective tax rate0.0%-10.7%0.0%0.0%0.2%-18.3%5.4%-6.2%5.3%4.5%4.0%1.9%-0.0%-0.0%0.0%
Net income$-2.88M$-3.66M$-6.44M$-15.83M$-24.98M$-26.27M$-40.38M$-48.44M$-48.67M$-56.54M$-58.12M$-66.15M$-57.28M$-23.36M$-1.00M
Net income growth (YoY)-26.9%-75.9%-146.0%-57.8%-5.1%-53.7%-20.0%-0.5%-16.2%-2.8%-13.8%+13.4%+59.2%+95.7%
Profit margin-5916.2%-1652.1%-1922.0%-2188.4%-10373.8%-3313.5%-5605.7%-1699.3%-291987.5%

Frequently asked questions

How much free cash flow does SYBX generate?

SYBX produced $-4.36M in free cash flow in its most recent fiscal year. Free cash flow is what is left after running and reinvesting in the business, and it is the cash that actually funds buybacks, dividends, and a stronger balance sheet.

Is SYBX's balance sheet healthy?

SYBX holds $14.67M in cash and equivalents against — in long-term debt, on $11.86M of shareholder equity. That debt is best read against the cash flow the business throws off each year.