WallStSmart
SNDX

Syndax Pharmaceuticals Inc

NASDAQ: SNDX · HEALTHCARE · BIOTECHNOLOGY

$21.38
-3.77% today

Updated 2026-06-05

Market cap
$1.76B
P/E ratio
P/S ratio
8.08x
EPS (TTM)
$-2.79
Dividend yield
52W range
$9 – $26
Volume
1.9M

Syndax Pharmaceuticals Inc (SNDX) Financial statements

SEC filings — annual and quarterly data.

Profit margin
-165.60%
Operating margin
-158.45%
ROE
-189.50%
ROA
-25.10%
Debt/equity
8.30x

Margin trends — annual

Gross margin Operating margin Profit margin
YearRevenueNet incomeGross marginOp. marginProfit margin
2011$-13.09M
2012$-9.96M
2013$-14.17M
2014$0.00$-19.83M
2015$627000.00$-24.12M100.00%-3,271.61%-3,846.73%
2016$1.22M$-44.47M100.00%-3,587.38%-3,645.25%
2017$2.11M$-60.80M100.00%-2,938.99%-2,884.35%
2018$1.52M$-73.96M100.00%-5,001.71%-4,875.48%
2019$1.52M$-55.95M100.00%-3,792.95%-3,688.53%
2020$1.52M$-73.07M100.00%-4,708.17%-4,816.68%
2021$139.71M$24.93M100.00%18.77%17.84%
2022$126.58M$-143.75M-0.36%-119.89%-113.57%
2023$0.00$-209.36M
2024$23.68M$-318.76M96.51%-1,434.43%-1,346.11%
2025$172.35M$-285.42M95.96%-158.45%-165.60%

Frequently asked questions

What is Syndax Pharmaceuticals Inc's revenue?

Syndax Pharmaceuticals Inc's trailing twelve-month revenue is $217.17M. Revenue is the top line the whole model builds on, and at this scale the question shifts from how fast it grows to whether margins hold as it compounds.

How profitable is SNDX?

In its most recent fiscal year, SNDX ran a gross margin of 95.96%, an operating margin of -158.45%, and a net margin of -165.60%. Margins this high mean most of each extra dollar of revenue drops through to profit, which is the signature of real pricing power.

How much free cash flow does SNDX generate?

SNDX produced $-323.17M in free cash flow in its most recent fiscal year. Free cash flow is what is left after running and reinvesting in the business, and it is the cash that actually funds buybacks, dividends, and a stronger balance sheet.

Is SNDX's balance sheet healthy?

SNDX holds $134.93M in cash and equivalents against $343.91M in long-term debt, on $64.63M of shareholder equity. That debt is best read against the cash flow the business throws off each year.