SLN
Silence Therapeutics PLC
NASDAQ: SLN · HEALTHCARE · BIOTECHNOLOGY
$7.31
+2.81% today
Updated 2026-04-30
Market cap
$363.70M
P/E ratio
—
P/S ratio
650.63x
EPS (TTM)
$-1.89
Dividend yield
—
52W range
$4 – $8
Volume
0.4M
Silence Therapeutics PLC (SLN) Financial statements
SEC filings — annual and quarterly data.
Income statement — annual
| Item | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $1.95M | $4.05M | $2.21M | $1.72M | $2.37M | $694000.00 | $163000.00 | $117000.00 | $15000.00 | — | $770000.00 | $16000.00 | $0.00 | $244000.00 | $5.48M | $12.41M | $21.66M | $25.38M | $43.26M | $559000.00 |
| Revenue growth (YoY) | — | +107.9% | -45.4% | -22.0% | +37.3% | -70.7% | -76.5% | -28.2% | -87.2% | -100.0% | — | -97.9% | -100.0% | — | +2145.5% | +126.6% | +74.4% | +17.2% | +70.5% | -98.7% |
| Cost of revenue | — | $4.84M | $6.71M | $5.07M | $5.82M | $3.36M | $3.38M | $5.65M | $8.88M | $7.11M | $8.71M | $7.94M | $9.74M | — | $3.76M | $7.46M | $13.46M | $10.32M | $11.81M | $215000.00 |
| Gross profit | $1.95M | $-796000.00 | $-4.50M | $-3.35M | $-3.46M | $-2.67M | $-3.21M | $-5.53M | $-8.87M | $-7.11M | $-7.94M | $-7.93M | $-9.74M | $244000.00 | $1.72M | $4.96M | $8.19M | $15.06M | $31.45M | $344000.00 |
| Gross margin | 100.0% | -19.7% | -203.8% | -194.4% | -146.0% | -384.3% | -1972.4% | -4727.4% | -59126.7% | — | -1031.3% | -49543.8% | — | 100.0% | 31.3% | 39.9% | 37.8% | 59.3% | 72.7% | 61.5% |
| R&D | $3.19M | $4.84M | $6.71M | $5.07M | $5.82M | $3.36M | $3.38M | $5.65M | $8.88M | $7.11M | $8.71M | $7.94M | $9.74M | $13.34M | $20.21M | $30.77M | $43.55M | $44.02M | $67.88M | $67.75M |
| SG&A | $3.03M | $4.99M | $3.29M | $3.19M | $5.13M | $2.65M | $2.61M | $3.54M | $3.26M | $2.65M | $3.96M | $6.46M | $10.83M | $9.64M | $13.98M | $20.01M | $25.68M | $20.64M | $26.88M | $22.34M |
| Operating income | $-4.27M | $-5.79M | $-7.79M | $-7.55M | $-8.66M | $-5.79M | $-26.31M | $-9.07M | $-12.13M | $-9.77M | $-11.91M | $-14.39M | $-20.57M | $-22.73M | $-35.85M | $-45.81M | $-61.04M | $-49.60M | $-63.32M | $-82.48M |
| Operating margin | -219.2% | -143.0% | -352.7% | -438.4% | -365.9% | -833.7% | -16143.6% | -7753.8% | -80846.7% | — | -1546.2% | -89943.8% | — | -9317.2% | -654.3% | -369.0% | -281.9% | -195.5% | -146.4% | -14755.3% |
| EBITDA | $-3.59M | $-5.32M | $-7.44M | $-7.12M | $-8.17M | $-5.42M | $-5.31M | $-8.78M | $-11.79M | $-9.59M | $-11.60M | $-3.33M | $-20.17M | $-22.36M | $-35.53M | $-45.42M | $-60.44M | $-49.78M | $-48.99M | $-89.20M |
| EBITDA margin | -184.2% | -131.4% | -336.8% | -413.1% | -345.3% | -780.8% | -3255.8% | -7500.0% | -78633.3% | — | -1506.0% | -20793.8% | — | -9161.9% | -648.5% | -365.9% | -279.1% | -196.2% | -113.2% | -15956.7% |
| EBIT | $-3.94M | $-5.63M | $-7.86M | $-7.49M | $-8.49M | $-5.72M | $-5.56M | $-9.07M | $-12.13M | $-9.77M | $-11.91M | $-3.76M | $-20.57M | $-22.84M | $-36.02M | $-45.85M | $-61.04M | $-50.28M | $-49.58M | $-89.75M |
| Interest expense | $20000.00 | $544000.00 | $31000.00 | $46000.00 | $63000.00 | $13000.00 | $30000.00 | $70000.00 | $147000.00 | $340000.00 | $1.54M | $15000.00 | $45000.00 | $33000.00 | $16000.00 | $8000.00 | $47000.00 | $34000.00 | — | — |
| Income tax | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Effective tax rate | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
| Net income | $-3.83M | $-5.11M | $-7.43M | $-7.47M | $-8.79M | $-5.74M | $-26.28M | $-9.00M | $-11.09M | $-6.64M | $-8.44M | $-1.62M | $-18.41M | $-19.58M | $-32.55M | $-39.41M | $-50.33M | $-43.27M | $-45.31M | $-88.61M |
| Net income growth (YoY) | — | -33.5% | -45.6% | -0.5% | -17.7% | +34.8% | -358.1% | +65.8% | -23.2% | +40.1% | -27.0% | +80.8% | -1037.9% | -6.4% | -66.2% | -21.1% | -27.7% | +14.0% | -4.7% | -95.6% |
| Profit margin | -196.5% | -126.2% | -336.6% | -433.6% | -371.7% | -826.7% | -16125.2% | -7694.0% | -73920.0% | — | -1096.1% | -10112.5% | — | -8025.4% | -594.0% | -317.4% | -232.4% | -170.5% | -104.7% | -15851.9% |