RYTM
Rhythm Pharmaceuticals Inc
NASDAQ: RYTM · HEALTHCARE · BIOTECHNOLOGY
$104.71
+2.46% today
Updated 2026-09-11
Market cap
$6.98B
P/E ratio
—
P/S ratio
29.11x
EPS (TTM)
$-3.12
Dividend yield
—
52W range
$75 – $122
Volume
0.6M
Rhythm Pharmaceuticals Inc (RYTM) Insider transactions
Net insider activity
Net buying (211,976 shares)
Buy transactions
44
Sell transactions
56
All transactions
| Date | Insider | Title | Type | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-08-31 | SMITH, HUNTER C | Chief Financial Officer | Sale | 57,187 | — | — |
| 2026-08-31 | SMITH, HUNTER C | Chief Financial Officer | Buy | 57,187 | $25.79 | $1.47M |
| 2026-08-31 | SMITH, HUNTER C | Chief Financial Officer | Sale | 28,188 | $106.20 | $2.99M |
| 2026-08-31 | SMITH, HUNTER C | Chief Financial Officer | Sale | 23,072 | $104.59 | $2.41M |
| 2026-08-31 | SMITH, HUNTER C | Chief Financial Officer | Sale | 11,514 | $105.37 | $1.21M |
| 2026-08-17 | JOSHI, MANHER | Chief Medical Officer | Buy | 50,000 | — | — |
| 2026-08-17 | JOSHI, MANHER | Chief Medical Officer | Buy | 25,000 | — | — |
| 2026-08-13 | SHULMAN, JOSEPH | Chief Technical Officer | Sale | 2,024 | — | — |
| 2026-08-13 | SHULMAN, JOSEPH | Chief Technical Officer | Sale | 5,079 | $119.75 | $608210.25 |
| 2026-08-13 | SHULMAN, JOSEPH | Chief Technical Officer | Buy | 2,024 | $6.80 | $13763.20 |
| 2026-08-13 | LEE, JENNIFER KAYDEN | EVP, Head of North America | Sale | 35,000 | — | — |
| 2026-08-13 | LEE, JENNIFER KAYDEN | EVP, Head of North America | Sale | 21,601 | — | — |
| 2026-08-13 | LEE, JENNIFER KAYDEN | EVP, Head of North America | Sale | 75,834 | $117.38 | $8.90M |
| 2026-08-13 | LEE, JENNIFER KAYDEN | EVP, Head of North America | Buy | 35,000 | $24.29 | $850150.00 |
| 2026-08-13 | LEE, JENNIFER KAYDEN | EVP, Head of North America | Buy | 21,601 | $6.80 | $146886.80 |
| 2026-08-13 | GARFIELD, ALASTAIR | Chief Scientific Officer | Sale | 3,400 | $118.28 | $402166.62 |
| 2026-08-13 | GARFIELD, ALASTAIR | Chief Scientific Officer | Sale | 2,007 | $116.11 | $233031.37 |
| 2026-08-13 | GARFIELD, ALASTAIR | Chief Scientific Officer | Sale | 1,556 | $117.08 | $182170.10 |
| 2026-08-13 | GARFIELD, ALASTAIR | Chief Scientific Officer | Sale | 800 | $119.17 | $95335.04 |
| 2026-08-12 | MAZABRAUD, YANN | EVP, Head of International | Sale | 46,625 | — | — |
| 2026-08-12 | MAZABRAUD, YANN | EVP, Head of International | Buy | 46,625 | $6.80 | $317050.00 |
| 2026-08-12 | MAZABRAUD, YANN | EVP, Head of International | Sale | 18,208 | $116.49 | $2.12M |
| 2026-08-12 | MAZABRAUD, YANN | EVP, Head of International | Sale | 17,319 | $117.47 | $2.03M |
| 2026-08-12 | MAZABRAUD, YANN | EVP, Head of International | Sale | 14,568 | $115.43 | $1.68M |
| 2026-08-12 | MAZABRAUD, YANN | EVP, Head of International | Sale | 3,605 | $114.70 | $413477.28 |
| 2026-08-12 | MAZABRAUD, YANN | EVP, Head of International | Sale | 2,300 | $111.80 | $257138.16 |
| 2026-08-12 | MAZABRAUD, YANN | EVP, Head of International | Sale | 1,000 | $112.86 | $112856.00 |
| 2026-07-01 | GARFIELD, ALASTAIR | Chief Scientific Officer | Sale | 4,445 | — | — |
| 2026-07-01 | GARFIELD, ALASTAIR | Chief Scientific Officer | Buy | 4,445 | — | — |
| 2026-07-01 | GARFIELD, ALASTAIR | Chief Scientific Officer | Sale | 2,150 | $110.41 | $237381.50 |
| 2026-06-24 | TETRAULT, LYNN A. | Director | Buy | 3,691 | — | — |
| 2026-06-24 | TETRAULT, LYNN A. | Director | Buy | 2,324 | — | — |
| 2026-06-24 | MCGIRR, DAVID W J | Director | Buy | 3,691 | — | — |
| 2026-06-24 | MCGIRR, DAVID W J | Director | Buy | 2,324 | — | — |
| 2026-06-24 | JEAN, CHRISTOPHE | Director | Buy | 3,691 | — | — |
| 2026-06-24 | JEAN, CHRISTOPHE | Director | Buy | 2,324 | — | — |
| 2026-06-24 | GOOD, JENNIFER L | Director | Buy | 3,691 | — | — |
| 2026-06-24 | GOOD, JENNIFER L | Director | Buy | 2,324 | — | — |
| 2026-06-24 | ARBUCKLE, STUART A | Director | Buy | 3,691 | — | — |
| 2026-06-24 | ARBUCKLE, STUART A | Director | Buy | 2,324 | — | — |
| 2026-06-23 | TETRAULT, LYNN A. | Director | Sale | 4,712 | — | — |
| 2026-06-23 | TETRAULT, LYNN A. | Director | Buy | 4,712 | — | — |
| 2026-06-23 | MCGIRR, DAVID W J | Director | Sale | 4,712 | — | — |
| 2026-06-23 | MCGIRR, DAVID W J | Director | Buy | 4,712 | — | — |
| 2026-06-23 | JEAN, CHRISTOPHE | Director | Sale | 4,712 | — | — |
| 2026-06-23 | JEAN, CHRISTOPHE | Director | Buy | 4,712 | — | — |
| 2026-06-23 | GOOD, JENNIFER L | Director | Sale | 4,712 | — | — |
| 2026-06-23 | GOOD, JENNIFER L | Director | Buy | 4,712 | — | — |
| 2026-06-23 | ARBUCKLE, STUART A | Director | Sale | 4,712 | — | — |
| 2026-06-23 | ARBUCKLE, STUART A | Director | Buy | 4,712 | — | — |
| 2026-06-22 | TETRAULT, LYNN A. | Director | Sale | 37,000 | — | — |
| 2026-06-22 | TETRAULT, LYNN A. | Director | Buy | 37,000 | $28.27 | $1.05M |
| 2026-05-18 | SMITH, HUNTER C | Chief Financial Officer | Sale | 3,000 | — | — |
| 2026-05-18 | SMITH, HUNTER C | Chief Financial Officer | Buy | 3,000 | $17.87 | $53610.00 |
| 2026-05-15 | GERMAN, CHRISTOPHER PAUL | Corporate Controller & CAO | Sale | 1,687 | — | — |
| 2026-05-15 | GERMAN, CHRISTOPHER PAUL | Corporate Controller & CAO | Sale | 1,406 | — | — |
| 2026-05-15 | GERMAN, CHRISTOPHER PAUL | Corporate Controller & CAO | Sale | 1,349 | — | — |
| 2026-05-15 | GERMAN, CHRISTOPHER PAUL | Corporate Controller & CAO | Sale | 4,643 | $92.21 | $428131.03 |
| 2026-05-15 | GERMAN, CHRISTOPHER PAUL | Corporate Controller & CAO | Buy | 1,687 | $56.69 | $95636.03 |
| 2026-05-15 | GERMAN, CHRISTOPHER PAUL | Corporate Controller & CAO | Buy | 1,406 | $17.97 | $25265.82 |
| 2026-05-15 | GERMAN, CHRISTOPHER PAUL | Corporate Controller & CAO | Buy | 1,349 | $49.23 | $66411.27 |
| 2026-04-01 | POPOVITS, KIMBERLY J | Director | Buy | 10,257 | — | — |
| 2026-04-01 | POPOVITS, KIMBERLY J | Director | Buy | 6,808 | — | — |
| 2026-04-01 | MAZABRAUD, YANN | EVP, Head of International | Sale | 10,375 | — | — |
| 2026-04-01 | MAZABRAUD, YANN | EVP, Head of International | Sale | 2,500 | — | — |
| 2026-04-01 | MAZABRAUD, YANN | EVP, Head of International | Buy | 12,875 | — | — |
| 2026-03-12 | MATHERS, EDWARD T | Director | Buy | 4,199 | — | — |
| 2026-03-04 | GERMAN, CHRISTOPHER PAUL | Corporate Controller & CAO | Sale | 1,500 | — | — |
| 2026-03-04 | GERMAN, CHRISTOPHER PAUL | Corporate Controller & CAO | Sale | 5,614 | $89.56 | $502789.84 |
| 2026-03-04 | GERMAN, CHRISTOPHER PAUL | Corporate Controller & CAO | Buy | 1,500 | $17.97 | $26955.00 |
| 2026-03-02 | SMITH, HUNTER C | Chief Financial Officer | Sale | 6,099 | — | — |
| 2026-03-02 | SMITH, HUNTER C | Chief Financial Officer | Buy | 6,099 | $6.80 | $41473.20 |
| 2026-03-02 | MAZABRAUD, YANN | EVP, Head of International | Buy | 35,000 | — | — |
| 2026-03-02 | MATHERS, EDWARD T | Director | Buy | 4,198 | — | — |
| 2026-03-01 | GERMAN, CHRISTOPHER PAUL | Corporate Controller & CAO | Sale | 1,162 | — | — |
| 2026-03-01 | GERMAN, CHRISTOPHER PAUL | Corporate Controller & CAO | Buy | 1,162 | — | — |
| 2026-03-01 | GERMAN, CHRISTOPHER PAUL | Corporate Controller & CAO | Sale | 342 | $94.94 | $32469.48 |
| 2026-02-19 | SMITH, HUNTER C | Chief Financial Officer | Sale | 1,692 | $100.92 | $170754.78 |
| 2026-02-19 | SMITH, HUNTER C | Chief Financial Officer | Sale | 1,308 | $100.27 | $131152.90 |
| 2026-02-19 | SMITH, HUNTER C | Chief Financial Officer | Sale | 800 | $102.10 | $81676.08 |
| 2026-02-19 | SMITH, HUNTER C | Chief Financial Officer | Sale | 585 | $103.28 | $60420.44 |
| 2026-02-17 | SMITH, HUNTER C | Chief Financial Officer | Sale | 1,200 | $99.42 | $119298.00 |
| 2026-02-17 | SMITH, HUNTER C | Chief Financial Officer | Sale | 1,069 | $103.00 | $110109.57 |
| 2026-02-17 | SMITH, HUNTER C | Chief Financial Officer | Sale | 900 | $101.70 | $91530.00 |
| 2026-02-17 | SMITH, HUNTER C | Chief Financial Officer | Sale | 200 | $103.84 | $20768.00 |
| 2026-02-14 | MAZABRAUD, YANN | EVP, Head of International | Sale | 10,000 | — | — |
| 2026-02-14 | MAZABRAUD, YANN | EVP, Head of International | Buy | 10,000 | — | — |
| 2026-02-12 | SMITH, HUNTER C | Chief Financial Officer | Sale | 800 | $98.99 | $79192.48 |
| 2026-02-12 | SMITH, HUNTER C | Chief Financial Officer | Sale | 400 | $97.67 | $39068.52 |
| 2026-02-12 | SMITH, HUNTER C | Chief Financial Officer | Sale | 292 | $96.26 | $28108.71 |
| 2026-02-12 | SMITH, HUNTER C | Chief Financial Officer | Sale | 100 | $100.10 | $10010.00 |
| 2026-02-11 | SMITH, HUNTER C | Chief Financial Officer | Buy | 37,500 | — | — |
| 2026-02-11 | SMITH, HUNTER C | Chief Financial Officer | Buy | 25,000 | — | — |
| 2026-02-11 | SMITH, HUNTER C | Chief Financial Officer | Sale | 2,266 | $98.37 | $222906.42 |
| 2026-02-11 | SMITH, HUNTER C | Chief Financial Officer | Sale | 400 | $99.44 | $39774.72 |
| 2026-02-11 | SMITH, HUNTER C | Chief Financial Officer | Sale | 100 | $100.85 | $10085.27 |
| 2026-02-11 | SHULMAN, JOSEPH | Chief Technical Officer | Buy | 22,500 | — | — |
| 2026-02-11 | SHULMAN, JOSEPH | Chief Technical Officer | Buy | 15,000 | — | — |
| 2026-02-11 | MEEKER, DAVID P | Director, President and CEO | Buy | 107,850 | — | — |
| 2026-02-11 | MEEKER, DAVID P | Director, President and CEO | Buy | 71,900 | — | — |
Frequently asked questions
Are RYTM insiders buying or selling?
Over the transactions on record, RYTM insiders have been net sellers, with about $26.08M in stock sold across 56 sales, against 12 open-market purchases.
Does insider selling at RYTM mean the stock will fall?
Not by itself. Most executive selling is pre-scheduled through 10b5-1 plans filed months in advance, and insiders sell for diversification, taxes, and liquidity far more often than out of any view on the price. Insider buying is the stronger signal, especially when several insiders buy around the same time, because there is usually only one reason to put personal cash into the stock.
Which RYTM insiders are selling the most?
Recent selling is concentrated in a few names. LEE, JENNIFER KAYDEN accounts for the largest share on record, with about $8.90M sold. Selling by one or two individuals matters less than broad selling across the whole leadership team, which is the pattern worth watching.