PRME
Prime Medicine, Inc. Common Stock
NASDAQ: PRME · HEALTHCARE · BIOTECHNOLOGY
$3.53
-4.34% today
Updated 2026-04-29
Market cap
$666.47M
P/E ratio
—
P/S ratio
143.88x
EPS (TTM)
$-1.35
Dividend yield
—
52W range
$1 – $7
Volume
2.5M
Prime Medicine, Inc. Common Stock (PRME) Earnings
Quarterly earnings history, analyst estimates, and stock price reaction.
EPS beat streak
8 of 8
Last 8 quarters
Avg EPS surprise
+11.6%
Last 4 quarters
Revenue YoY growth
-61.6%
Most recent quarter
EPS YoY growth
+22.6%
Most recent quarter
Earnings surprise history (last 12 quarters)
Beat estimate Missed estimate
Quarterly EPS and revenue trend
Quarterly revenue EPS (diluted)
How the stock reacts to earnings
Avg 1-day reaction
-13.6%
Last 2 reports
Positive reaction rate
0%
0 of 2 quarters
Largest single-day move
-15.7%
2025-11-07
| Report date | EPS actual | Surprise | Close before | Close after | 1-day reaction |
|---|---|---|---|---|---|
| 2026-03-03 | $-0.24 | +6.9% | $4.66 | $4.12 | -11.6% |
| 2025-11-07 | $-0.32 | +25.6% | $4.18 | $3.53 | -15.7% |
Quarterly earnings history
| Fiscal quarter ending | EPS estimate | EPS actual | Surprise | Revenue | YoY revenue |
|---|---|---|---|---|---|
| 2025-12-31 | $-0.26 | $-0.24 | +6.9% | $838000.00 | -61.6% |
| 2025-09-30 | $-0.43 | $-0.32 | +25.6% | $1.23M | +486.1% |
| 2025-06-30 | $-0.43 | $-0.41 | +4.7% | $1.11M | -97.0% |
| 2025-03-31 | $-0.44 | $-0.40 | +9.1% | $1.45M | +146.0% |
| 2024-12-31 | $-0.49 | $-0.31 | +36.7% | $2.18M | -91.5% |
| 2024-09-30 | $-0.49 | $-0.44 | +10.2% | $209000.00 | — |
| 2024-06-30 | $-0.49 | $-0.46 | +6.1% | $37.77M | — |
| 2024-03-31 | $-0.47 | $-0.44 | +6.4% | $591000.00 | — |
| 2023-12-31 | $-0.51 | $-0.72 | -41.2% | $25.69M | — |
| 2023-09-30 | $-0.46 | $-0.55 | -19.6% | — | — |
| 2023-06-30 | $-0.42 | $-0.47 | -11.9% | — | — |
| 2023-03-31 | $-0.41 | $-0.44 | -7.3% | — | — |
Frequently asked questions
Has Prime Medicine, Inc. Common Stock beaten earnings estimates?
Prime Medicine, Inc. Common Stock has beaten Wall Street EPS estimates in 8 of its last 8 quarterly reports, with an average EPS surprise of +11.6% over the last 4 quarters.
How does PRME stock react to earnings?
PRME stock has moved an average of -13.6% in the trading day following earnings over its last 2 reports, with positive reactions in 0% of those quarters.
What is Prime Medicine, Inc. Common Stock's revenue growth rate?
Prime Medicine, Inc. Common Stock reported year-over-year revenue growth of -61.6% in its most recent quarter, with EPS growing +22.6% year-over-year.