WallStSmart
PLSE

Pulse Biosciences Inc

NASDAQ: PLSE · HEALTHCARE · MEDICAL INSTRUMENTS & SUPPLIES

$21.17
+4.75% today

Updated 2026-04-30

Market cap
$1.48B
P/E ratio
P/S ratio
4,240.58x
EPS (TTM)
$-1.08
Dividend yield
52W range
$13 – $26
Volume
0.3M

Pulse Biosciences Inc (PLSE) Stock Valuation Analysis

Fair value estimate, historical valuation range, and quality signals for PLSE.

WallStSmart Verdict
Overvalued

Current price exceeds what fundamentals support. Risk/reward skewed unfavorably.

Smart Value Score: 16 / 100
P/E (TTM)
Not meaningful for this profile
PEG
Margin of Safety
DCF limited for this profile
EV / EBITDA
-1.8x

PLSE historical valuation range

Where current P/E sits in PLSE's own 5Y range.

Insufficient historical data for 5Y percentile analysis

PLSE intrinsic value (DCF)

DCF-based fair value estimate vs current market price.

DCF has limited applicability for PLSE

Standard discounted cash flow models produce unreliable output for unprofitable or near-breakeven companies. Revenue-based multiples such as P/S and EV/Sales, combined with the historical valuation position above, give a more reliable read for this stock.

Intrinsic value calculated using discounted cash flow (DCF) model based on projected free cash flows, discount rate, and terminal growth assumptions. A positive margin of safety indicates the current price is below estimated fair value, providing a cushion against estimation error.

PLSE valuation signals

Quick-read green flags, caution flags, and risks based on current metrics.

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DCF limited applicability
Company profile produces unstable DCF output. Lean on P/S, EV/Sales, and historical valuation position instead of intrinsic value for this stock.
Weak financial quality
Piotroski F-Score of 3/9 suggests deteriorating fundamentals. Valuation requires closer scrutiny.

P/E Ratio — History

No historical P/E data available

P/S Ratio — History

Current: 4240.58x

Is PLSE overvalued in 2026?

Pulse Biosciences Inc (PLSE) currently trades at $21.17 per share with a market capitalization of $1,484,202,000.00. Based on our multi-factor framework, the stock appears richly valued with a Smart Value Score of 16/100. This score blends growth quality, financial health, and price attractiveness into a single institutional-grade read.

PLSE currently has no meaningful P/E ratio, which typically signals that the company is unprofitable, near breakeven, or emerging from a loss-making period. With a P/S ratio of 4240.6x, the market is valuing the company primarily on its revenue rather than its earnings.

A standard DCF model does not produce reliable output for PLSE under current conditions. For unprofitable or near-breakeven companies, revenue-based multiples such as EV/Sales and historical P/S percentile are more informative than intrinsic value calculations.

Financial quality is a concern. The Piotroski F-Score of 3/9 flags weakening fundamentals that deserve closer scrutiny before the valuation case can be fully trusted.

Bottom line: PLSE appears richly valued on our framework, with a Smart Value Score of 16/100. At current levels the risk/reward is skewed against the buyer. A materially lower price or significant operational improvement would be needed to change the picture.

Frequently asked questions

Is PLSE overvalued in 2026?

Based on a Smart Value Score of 16/100, PLSE appears overvalued. Current price exceeds what fundamentals currently justify.

What is PLSE's fair value?

Standard DCF is unreliable for PLSE due to its current profitability profile. Revenue-based approaches such as EV/Sales or historical P/S percentile are more informative for this stock.

What P/E ratio does PLSE trade at?

PLSE does not have a meaningful P/E ratio at this time, typically a sign of unprofitability or an ongoing earnings transition.

Is PLSE a buy based on valuation?

WallStSmart does not issue buy or sell recommendations. Our Smart Value Score of 16/100 reflects the combined read on growth, quality, and price. The profile skews cautious. Consider waiting for a better price or clearer operational improvement.

How does PLSE's valuation compare to its history?

Insufficient historical valuation data exists yet for a confident percentile read on PLSE.

What is PLSE's Smart Value Score?

PLSE's Smart Value Score is 16/100. The Smart Value Score is a proprietary WallStSmart metric blending growth quality, financial health, and valuation attractiveness into a single 0-100 read. Scores above 75 are rare and indicate strong multi-factor alignment.