Pfizer Inc
NYSE: PFE · HEALTHCARE · DRUG MANUFACTURERS - GENERAL
Updated 2026-04-29
Pfizer Inc (PFE) Stock Valuation Analysis
Fair value estimate, historical valuation range, and quality signals for PFE.
Current price exceeds what fundamentals support. Risk/reward skewed unfavorably.
PFE historical valuation range
Where current P/E sits in PFE's own 5Y range.
PFE intrinsic value (DCF)
DCF-based fair value estimate vs current market price.
Intrinsic value calculated using discounted cash flow (DCF) model based on projected free cash flows, discount rate, and terminal growth assumptions. A positive margin of safety indicates the current price is below estimated fair value, providing a cushion against estimation error.
PFE valuation signals
Quick-read green flags, caution flags, and risks based on current metrics.
P/E Ratio — History
Current: 19.85x
P/S Ratio — History
Current: 2.45x
Is PFE overvalued in 2026?
Pfizer Inc (PFE) currently trades at $26.70 per share with a market capitalization of $153,585,615,000.00. Based on our multi-factor framework, the stock appears richly valued with a Smart Value Score of 49/100. This score blends growth quality, financial health, and price attractiveness into a single institutional-grade read.
The stock trades at a P/E ratio of 19.9x, above its 5-year median of 12.7x. The PEG ratio of 13.77 indicates the price has run ahead of the underlying growth rate.
Looking at its own history, PFE is currently trading more expensive than 84% of the last 5Y on P/E. This places it in the 84th percentile of its historical range, a zone where forward returns have typically been muted.
Our discounted cash flow model estimates PFE's intrinsic value at $37.19 per share, against the current market price of $26.70. This implies a margin of safety of +29.36%. A meaningful cushion exists against model error, making this a reasonable risk-adjusted entry.
Financial quality is a concern. The Piotroski F-Score of 3/9 flags weakening fundamentals that deserve closer scrutiny before the valuation case can be fully trusted.
Bottom line: PFE appears richly valued on our framework, with a Smart Value Score of 49/100. At current levels the risk/reward is skewed against the buyer. A materially lower price or significant operational improvement would be needed to change the picture.
Frequently asked questions
Is PFE overvalued in 2026?
Based on a Smart Value Score of 49/100, PFE appears overvalued. Current price exceeds what fundamentals currently justify.
What is PFE's fair value?
Our DCF model estimates PFE's intrinsic value at $37.19 per share, versus the current price of $26.70. This produces a margin of safety of +29.36%.
What P/E ratio does PFE trade at?
PFE trades at a P/E of 19.9x on trailing twelve-month earnings, compared to its 5-year median of 12.7x.
Is PFE a buy based on valuation?
WallStSmart does not issue buy or sell recommendations. Our Smart Value Score of 49/100 reflects the combined read on growth, quality, and price. The profile skews cautious. Consider waiting for a better price or clearer operational improvement.
How does PFE's valuation compare to its history?
On P/E, PFE currently sits in the 84th percentile of its own 5Y range. That is historically expensive relative to where it has traded over the period.
What is PFE's Smart Value Score?
PFE's Smart Value Score is 49/100. The Smart Value Score is a proprietary WallStSmart metric blending growth quality, financial health, and valuation attractiveness into a single 0-100 read. Scores above 75 are rare and indicate strong multi-factor alignment.