Palisade Bio Inc
NASDAQ: PALI · HEALTHCARE · BIOTECHNOLOGY
Updated 2026-10-28
Palisade Bio Inc (PALI) Stock Valuation Analysis
Fair value estimate, historical valuation range, and quality signals for PALI.
Current price exceeds what fundamentals support. Risk/reward skewed unfavorably.
PALI historical valuation range
Where current P/E sits in PALI's own 5Y range.
PALI intrinsic value (DCF)
DCF-based fair value estimate vs current market price.
Intrinsic value calculated using discounted cash flow (DCF) model based on projected free cash flows, discount rate, and terminal growth assumptions. A positive margin of safety indicates the current price is below estimated fair value, providing a cushion against estimation error.
PALI valuation signals
Quick-read green flags, caution flags, and risks based on current metrics.
P/E Ratio — History
Current: 2.22x
P/S Ratio — History
Current: 463.56x
Is PALI overvalued in 2026?
Palisade Bio Inc (PALI) currently trades at $1.19 per share with a market capitalization of $231,780,000.00. Based on our multi-factor framework, the stock appears richly valued with a Smart Value Score of 21/100. This score blends growth quality, financial health, and price attractiveness into a single institutional-grade read.
The stock trades at a P/E ratio of 2.2x, below its 5-year median of 3.2x.
Looking at its own history, PALI is currently trading cheaper than 75% of the last 5Y on P/E. This places it in the 25th percentile of its historical range, a reasonable but unremarkable position.
Our discounted cash flow model estimates PALI's intrinsic value at $3.87 per share, against the current market price of $1.19. This implies a margin of safety of +55.04%. A meaningful cushion exists against model error, making this a reasonable risk-adjusted entry.
Financial quality is a concern. The Piotroski F-Score of 3/9 flags weakening fundamentals that deserve closer scrutiny before the valuation case can be fully trusted.
Bottom line: PALI appears richly valued on our framework, with a Smart Value Score of 21/100. At current levels the risk/reward is skewed against the buyer. A materially lower price or significant operational improvement would be needed to change the picture.
Frequently asked questions
Is PALI overvalued?
PALI scores 21/100 on our Smart Value Score (Grade F), a weak overall profile. The DCF also shows a positive margin of safety, so price and fundamentals line up reasonably well.
What is PALI's fair value?
Our DCF model estimates PALI's intrinsic value at $3.87 per share, versus the current price of $1.19, a margin of safety of +55.04%. Fair value is the present value of the cash flows we project the business to produce, so a price below it means the market is pricing the stock below that conservative estimate.
What P/E ratio does PALI trade at?
PALI trades at a P/E of 2.2x on trailing twelve-month earnings, against a 5-year median of 3.2x. P/E is what you pay per dollar of profit, and sitting below its own median means the stock is cheaper than usual relative to its earnings.
Is PALI a buy based on valuation?
Our Smart Value rating for PALI is Strong Sell, from a Smart Value Score of 21/100 that blends growth, quality, and valuation. The profile skews cautious, and a better price or clearer operating improvement would strengthen the case. This is research to inform your decision, not personalized financial advice.
How does PALI's valuation compare to its history?
On P/E, PALI sits in the 25th percentile of its own 5Y range, below its long-run median relative to where it has traded. A low percentile means today's multiple is near the bottom of its historical band.
What is PALI's Smart Value Score?
PALI's Smart Value Score is 21/100. It is a proprietary WallStSmart metric blending growth quality, financial health, and valuation into a single 0-100 read, and scores above 75 are rare, signaling strong multi-factor alignment.