Krystal Biotech Inc
NASDAQ: KRYS · HEALTHCARE · BIOTECHNOLOGY
Updated 2026-06-05
Krystal Biotech Inc (KRYS) Financial statements
SEC filings — annual and quarterly data.
Cash flow — annual
| Item | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|---|
| Operating cash flow | $-1.31M | $-3.89M | $-9.45M | $-18.71M | $-26.08M | $-47.94M | $-100.57M | $-88.80M | $123.42M | $200.87M |
| Capital expenditures | $15000.00 | $210000.00 | $2.23M | $6.40M | $14.84M | $68.34M | $52.98M | $11.80M | $4.24M | $11.95M |
| Depreciation | $2000.00 | $23000.00 | $141000.00 | $748000.00 | $1.85M | $2.77M | $4.05M | $5.01M | $6.71M | — |
| Stock-based comp | $33000.00 | $246000.00 | $792000.00 | $1.24M | $3.27M | $15.32M | $33.23M | $39.93M | $49.13M | $54.51M |
| Free cash flow | $-1.33M | $-4.10M | $-11.68M | $-25.11M | $-40.93M | $-116.27M | $-153.55M | $-100.60M | $119.18M | $188.91M |
| Investing cash flow | $-15000.00 | $-210000.00 | $-10.32M | $-4.97M | $-11.18M | $-226.77M | $-114.08M | $82.64M | $-163.44M | — |
| Financing cash flow | $3.25M | $51.77M | $73.85M | $107.53M | $118.02M | $347.69M | $35.35M | $202.75M | $27.01M | — |
| Dividends paid | — | $0.00 | — | — | — | — | — | — | — | — |
| Share repurchases | — | — | — | — | — | — | — | — | — | — |
| Debt repayment | — | — | — | — | — | — | — | — | — | — |
| Net change in cash | — | $47.67M | — | $83.84M | $80.75M | $72.98M | — | — | — | — |
Frequently asked questions
What is Krystal Biotech Inc's revenue?
Krystal Biotech Inc's trailing twelve-month revenue is $417.30M, and consensus projects about $1.43T by 2030. Revenue is the top line the whole model builds on, and at this scale the question shifts from how fast it grows to whether margins hold as it compounds.
How profitable is KRYS?
In its most recent fiscal year, KRYS ran a gross margin of 92.61%, an operating margin of 41.45%, and a net margin of 52.64%. Margins this high mean most of each extra dollar of revenue drops through to profit, which is the signature of real pricing power.
How much free cash flow does KRYS generate?
KRYS produced $188.91M in free cash flow in its most recent fiscal year. Free cash flow is what is left after running and reinvesting in the business, and it is the cash that actually funds buybacks, dividends, and a stronger balance sheet.
Is KRYS's balance sheet healthy?
KRYS holds $496.30M in cash and equivalents against — in long-term debt, on $1.22B of shareholder equity. That debt is best read against the cash flow the business throws off each year.