KPTI
Karyopharm Therapeutics Inc
NASDAQ: KPTI · HEALTHCARE · BIOTECHNOLOGY
$8.31
-1.07% today
Updated 2026-04-30
Market cap
$195.22M
P/E ratio
—
P/S ratio
1.34x
EPS (TTM)
$-17.80
Dividend yield
—
52W range
$4 – $11
Volume
1.0M
Karyopharm Therapeutics Inc (KPTI) Earnings
Quarterly earnings history, analyst estimates, and stock price reaction.
EPS beat streak
5 of 8
Last 8 quarters
Avg EPS surprise
-66.6%
Last 4 quarters
Revenue YoY growth
+11.6%
Most recent quarter
EPS YoY growth
-58.1%
Most recent quarter
Earnings surprise history (last 12 quarters)
Beat estimate Missed estimate
Quarterly EPS and revenue trend
Quarterly revenue EPS (diluted)
How the stock reacts to earnings
Avg 1-day reaction
+4.4%
Last 2 reports
Positive reaction rate
50%
1 of 2 quarters
Largest single-day move
+16.4%
2026-02-12
| Report date | EPS actual | Surprise | Close before | Close after | 1-day reaction |
|---|---|---|---|---|---|
| 2026-02-12 | $-5.69 | -2577.6% | $7.37 | $8.58 | +16.4% |
| 2025-11-05 | $-3.82 | -72.9% | $5.65 | $5.22 | -7.6% |
Quarterly earnings history
| Fiscal quarter ending | EPS estimate | EPS actual | Surprise | Revenue | YoY revenue |
|---|---|---|---|---|---|
| 2025-12-31 | $-0.21 | $-5.69 | -2577.6% | $34.08M | +11.6% |
| 2025-09-30 | $-2.21 | $-3.82 | -72.9% | $44.04M | +13.6% |
| 2025-06-30 | $-3.91 | $-4.07 | -4.1% | $37.93M | -11.4% |
| 2025-03-31 | $-3.09 | $-2.77 | +10.4% | $30.02M | -9.4% |
| 2024-12-31 | $-4.03 | $-3.60 | +10.7% | $30.54M | -9.5% |
| 2024-09-30 | $-3.92 | $-3.90 | +0.5% | $38.78M | +7.7% |
| 2024-06-30 | $-0.30 | $0.15 | +150.0% | $42.79M | +13.9% |
| 2024-03-31 | $-0.33 | $-0.32 | +3.0% | $33.13M | -14.4% |
| 2023-12-31 | $-0.31 | $-0.36 | -16.1% | $33.75M | — |
| 2023-09-30 | $-0.28 | $-0.30 | -7.1% | $36.01M | — |
| 2023-06-30 | $-0.34 | $-0.29 | +14.7% | $37.58M | — |
| 2023-03-31 | $-0.37 | $-0.30 | +18.9% | $38.70M | — |
Frequently asked questions
Has Karyopharm Therapeutics Inc beaten earnings estimates?
Karyopharm Therapeutics Inc has beaten Wall Street EPS estimates in 5 of its last 8 quarterly reports, with an average EPS surprise of -66.6% over the last 4 quarters.
How does KPTI stock react to earnings?
KPTI stock has moved an average of +4.4% in the trading day following earnings over its last 2 reports, with positive reactions in 50% of those quarters.
What is Karyopharm Therapeutics Inc's revenue growth rate?
Karyopharm Therapeutics Inc reported year-over-year revenue growth of +11.6% in its most recent quarter, with EPS growing -58.1% year-over-year.