WallStSmart
IOVA

Iovance Biotherapeutics Inc

NASDAQ: IOVA · HEALTHCARE · BIOTECHNOLOGY

$3.52
-7.56% today

Updated 2026-06-03

Market cap
$1.84B
P/E ratio
P/S ratio
6.46x
EPS (TTM)
$-0.92
Dividend yield
52W range
$2 – $6
Volume
14.3M

Iovance Biotherapeutics Inc (IOVA) Financial statements

SEC filings — annual and quarterly data.

Profit margin
-148.38%
Operating margin
-153.08%
ROE
-47.50%
ROA
-23.60%
Debt/equity
0.06x

Margin trends — annual

Gross margin Operating margin Profit margin
YearRevenueNet incomeGross marginOp. marginProfit margin
2008$-57140.00
2009$-15772.00
2010$-1.61M
2011$0.00$-25.69M
2012$0.00$-3.31M
2013$0.00$-25.38M
2014$0.00$-12.04M
2015$0.00$-27.66M
2016$0.00$-52.89M
2017$0.00$-92.06M
2018$0.00$-123.58M
2019$0.00$-187.07M
2020$0.00$-259.58M
2021$0.00$-327.82M
2022$238000.00$-389.92M-8,880.25%-167,595.80%-163,833.19%
2023$1.19M$-444.04M-804.54%-38,734.99%-37,345.42%
2024$164.07M$-372.18M24.43%-240.92%-226.84%
2025$263.50M$-390.98M97.23%-153.08%-148.38%

Frequently asked questions

What is Iovance Biotherapeutics Inc's revenue?

Iovance Biotherapeutics Inc's trailing twelve-month revenue is $285.61M. Revenue is the top line the whole model builds on, and at this scale the question shifts from how fast it grows to whether margins hold as it compounds.

How profitable is IOVA?

In its most recent fiscal year, IOVA ran a gross margin of 97.23%, an operating margin of -153.08%, and a net margin of -148.38%. Margins this high mean most of each extra dollar of revenue drops through to profit, which is the signature of real pricing power.

How much free cash flow does IOVA generate?

IOVA produced $-336.24M in free cash flow in its most recent fiscal year. Free cash flow is what is left after running and reinvesting in the business, and it is the cash that actually funds buybacks, dividends, and a stronger balance sheet.

Is IOVA's balance sheet healthy?

IOVA holds $163.08M in cash and equivalents against — in long-term debt, on $698.58M of shareholder equity. That debt is best read against the cash flow the business throws off each year.