WallStSmart
COLL

Collegium Pharmaceutical Inc

NASDAQ: COLL · HEALTHCARE · DRUG MANUFACTURERS - SPECIALTY & GENERIC

$22.75
-0.74% today

Updated 2026-09-11

Market cap
$724.14M
P/E ratio
18.39
P/S ratio
0.90x
EPS (TTM)
$1.27
Dividend yield
52W range
$23 – $51
Volume
0.7M

Collegium Pharmaceutical Inc (COLL) Stock Valuation Analysis

Fair value estimate, historical valuation range, and quality signals for COLL.

WallStSmart Verdict
Overvalued

Current price exceeds what fundamentals support. Risk/reward skewed unfavorably.

Smart Value Score: 48 / 100
P/E (TTM)
18.4x
vs 5Y median of 19.0x
PEG
Margin of Safety
+88.54%
Fair value $393.86 vs $22.75
EV / EBITDA
4.5x

COLL historical valuation range

Where current P/E sits in COLL's own 5Y range.

NOW
7.5x
5Y Low
16.8x
25th
19.0x
Median
21.4x
75th
149.0x
5Y High
COLL is trading cheaper than 53% of the last 5Y.
47th percentile · Below median

COLL intrinsic value (DCF)

DCF-based fair value estimate vs current market price.

Current price
$22.75
Market value
Intrinsic value
$393.86
DCF estimate
Margin of safety
+88.54%
+1631.3% upside to fair value

Intrinsic value calculated using discounted cash flow (DCF) model based on projected free cash flows, discount rate, and terminal growth assumptions. A positive margin of safety indicates the current price is below estimated fair value, providing a cushion against estimation error.

COLL valuation signals

Quick-read green flags, caution flags, and risks based on current metrics.

!
P/E in mid-range
P/E sits at the 47th percentile of the 5Y range. Neither cheap nor rich historically.
Strong margin of safety
Current price 88.5% below DCF intrinsic value estimate. Meaningful downside cushion.

P/E Ratio — History

Current: 18.39x

P/S Ratio — History

Current: 0.90x

Is COLL overvalued in 2026?

Collegium Pharmaceutical Inc (COLL) currently trades at $22.75 per share with a market capitalization of $724,141,000.00. Based on our multi-factor framework, the stock appears richly valued with a Smart Value Score of 48/100. This score blends growth quality, financial health, and price attractiveness into a single institutional-grade read.

The stock trades at a P/E ratio of 18.4x, below its 5-year median of 19.0x.

Looking at its own history, COLL is currently trading cheaper than 53% of the last 5Y on P/E. This places it in the 47th percentile of its historical range, a reasonable but unremarkable position.

Our discounted cash flow model estimates COLL's intrinsic value at $393.86 per share, against the current market price of $22.75. This implies a margin of safety of +88.54%. A meaningful cushion exists against model error, making this a reasonable risk-adjusted entry.

The Piotroski F-Score of 5/9 puts financial quality in a middling range, neither a standout strength nor an obvious red flag.

Bottom line: COLL appears richly valued on our framework, with a Smart Value Score of 48/100. At current levels the risk/reward is skewed against the buyer. A materially lower price or significant operational improvement would be needed to change the picture.

Frequently asked questions

Is COLL overvalued?

COLL scores 48/100 on our Smart Value Score (Grade C), a weak overall profile. The DCF also shows a positive margin of safety, so price and fundamentals line up reasonably well.

What is COLL's fair value?

Our DCF model estimates COLL's intrinsic value at $393.86 per share, versus the current price of $22.75, a margin of safety of +88.54%. Fair value is the present value of the cash flows we project the business to produce, so a price below it means the market is pricing the stock below that conservative estimate.

What P/E ratio does COLL trade at?

COLL trades at a P/E of 18.4x on trailing twelve-month earnings, against a 5-year median of 19.0x. P/E is what you pay per dollar of profit, and sitting below its own median means the stock is cheaper than usual relative to its earnings.

Is COLL a buy based on valuation?

Our Smart Value rating for COLL is Sell, from a Smart Value Score of 48/100 that blends growth, quality, and valuation. The profile skews cautious, and a better price or clearer operating improvement would strengthen the case. This is research to inform your decision, not personalized financial advice.

How does COLL's valuation compare to its history?

On P/E, COLL sits in the 47th percentile of its own 5Y range, below its long-run median relative to where it has traded. A low percentile means today's multiple is near the bottom of its historical band.

What is COLL's Smart Value Score?

COLL's Smart Value Score is 48/100. It is a proprietary WallStSmart metric blending growth quality, financial health, and valuation into a single 0-100 read, and scores above 75 are rare, signaling strong multi-factor alignment.