WallStSmart
CDNA

CareDx Inc

NASDAQ: CDNA · HEALTHCARE · DIAGNOSTICS & RESEARCH

$20.81
+0.05% today

Updated 2026-04-30

Market cap
$1.09B
P/E ratio
P/S ratio
2.86x
EPS (TTM)
$-0.40
Dividend yield
52W range
$11 – $23
Volume
0.7M

CareDx Inc (CDNA) Stock Valuation Analysis

Fair value estimate, historical valuation range, and quality signals for CDNA.

WallStSmart Verdict
Overvalued

Current price exceeds what fundamentals support. Risk/reward skewed unfavorably.

Smart Value Score: 34 / 100
P/E (TTM)
Not meaningful for this profile
PEG
Margin of Safety
+63.35%
Fair value $53.80 vs $20.81
EV / EBITDA
65.5x

CDNA historical valuation range

Where current P/E sits in CDNA's own 5Y range.

Insufficient historical data for 5Y percentile analysis

CDNA intrinsic value (DCF)

DCF-based fair value estimate vs current market price.

Current price
$20.81
Market value
Intrinsic value
$53.80
DCF estimate
Margin of safety
+63.35%
+158.5% upside to fair value

Intrinsic value calculated using discounted cash flow (DCF) model based on projected free cash flows, discount rate, and terminal growth assumptions. A positive margin of safety indicates the current price is below estimated fair value, providing a cushion against estimation error.

CDNA valuation signals

Quick-read green flags, caution flags, and risks based on current metrics.

Strong margin of safety
Current price 63.4% below DCF intrinsic value estimate. Meaningful downside cushion.
Weak financial quality
Piotroski F-Score of 0/9 suggests deteriorating fundamentals. Valuation requires closer scrutiny.

P/E Ratio — History

P/S Ratio — History

Current: 2.86x

Is CDNA overvalued in 2026?

CareDx Inc (CDNA) currently trades at $20.81 per share with a market capitalization of $1,087,323,000.00. Based on our multi-factor framework, the stock appears richly valued with a Smart Value Score of 34/100. This score blends growth quality, financial health, and price attractiveness into a single institutional-grade read.

CDNA currently has no meaningful P/E ratio, which typically signals that the company is unprofitable, near breakeven, or emerging from a loss-making period. With a P/S ratio of 2.9x, the market is valuing the company primarily on its revenue rather than its earnings.

Our discounted cash flow model estimates CDNA's intrinsic value at $53.80 per share, against the current market price of $20.81. This implies a margin of safety of +63.35%. A meaningful cushion exists against model error, making this a reasonable risk-adjusted entry.

Financial quality is a concern. The Piotroski F-Score of 0/9 flags weakening fundamentals that deserve closer scrutiny before the valuation case can be fully trusted.

Bottom line: CDNA appears richly valued on our framework, with a Smart Value Score of 34/100. At current levels the risk/reward is skewed against the buyer. A materially lower price or significant operational improvement would be needed to change the picture.

Frequently asked questions

Is CDNA overvalued in 2026?

Based on a Smart Value Score of 34/100, CDNA appears overvalued. Current price exceeds what fundamentals currently justify.

What is CDNA's fair value?

Our DCF model estimates CDNA's intrinsic value at $53.80 per share, versus the current price of $20.81. This produces a margin of safety of +63.35%.

What P/E ratio does CDNA trade at?

CDNA does not have a meaningful P/E ratio at this time, typically a sign of unprofitability or an ongoing earnings transition.

Is CDNA a buy based on valuation?

WallStSmart does not issue buy or sell recommendations. Our Smart Value Score of 34/100 reflects the combined read on growth, quality, and price. The profile skews cautious. Consider waiting for a better price or clearer operational improvement.

How does CDNA's valuation compare to its history?

Insufficient historical valuation data exists yet for a confident percentile read on CDNA.

What is CDNA's Smart Value Score?

CDNA's Smart Value Score is 34/100. The Smart Value Score is a proprietary WallStSmart metric blending growth quality, financial health, and valuation attractiveness into a single 0-100 read. Scores above 75 are rare and indicate strong multi-factor alignment.