CBIO
Crescent Biopharma, Inc.
NASDAQ: CBIO · HEALTHCARE · BIOTECHNOLOGY
$13.50
+1.73% today
Updated 2026-10-28
Market cap
$459.13M
P/E ratio
—
P/S ratio
38.64x
EPS (TTM)
$-7.63
Dividend yield
—
52W range
$9 – $27
Volume
0.4M
Crescent Biopharma, Inc. (CBIO) Insider transactions
Net insider activity
Net buying (4,102,485 shares)
Buy transactions
39
Sell transactions
61
All transactions
| Date | Insider | Title | Type | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-08-03 | WESTON, CLAIRE | Director | Buy | 40,000 | — | — |
| 2026-08-03 | KIRKBY, MAXWELL | Director | Buy | 40,000 | — | — |
| 2026-06-18 | YE, WEIGUO | Chief Operating Officer | Sale | 3,000 | — | — |
| 2026-06-18 | YE, WEIGUO | Chief Operating Officer | Sale | 3,000 | $6.35 | $19050.00 |
| 2026-06-11 | YE, WEIGUO | Chief Operating Officer | Sale | 2,800 | — | — |
| 2026-06-11 | YE, WEIGUO | Chief Operating Officer | Sale | 2,800 | $6.17 | $17276.00 |
| 2026-06-10 | ZHANG, PING | Director | Buy | 40,000 | — | — |
| 2026-06-10 | YE, WEIGUO | Chief Operating Officer | Sale | 6,418 | — | — |
| 2026-06-10 | YE, WEIGUO | Chief Operating Officer | Sale | 5,000 | — | — |
| 2026-06-10 | YE, WEIGUO | Chief Operating Officer | Sale | 6,418 | $6.21 | $39855.78 |
| 2026-06-10 | YE, WEIGUO | Chief Operating Officer | Sale | 5,000 | $6.24 | $31200.00 |
| 2026-06-10 | WENG, DAN | Director | Buy | 40,000 | — | — |
| 2026-06-10 | PARRY, RENATE | Director | Buy | 40,000 | — | — |
| 2026-06-10 | NUSSBAUM, RODNEY L | Director | Buy | 40,000 | — | — |
| 2026-06-10 | EPSTEIN, DAVID M. | Director | Buy | 40,000 | — | — |
| 2026-06-10 | CARMICHAEL, GORDON | Director | Buy | 40,000 | — | — |
| 2026-06-09 | YE, WEIGUO | Chief Operating Officer | Sale | 14,500 | — | — |
| 2026-06-09 | YE, WEIGUO | Chief Operating Officer | Sale | 3,000 | — | — |
| 2026-06-09 | YE, WEIGUO | Chief Operating Officer | Buy | 14,500 | $0.75 | $10875.00 |
| 2026-06-09 | YE, WEIGUO | Chief Operating Officer | Sale | 3,000 | $6.15 | $18450.00 |
| 2026-06-08 | LUO, YING | Director, Chief Executive Officer | Buy | 120,000 | — | — |
| 2026-06-08 | BERGMANN, JOSHUA BENJAMIN | GC and Corporate Secretary | Buy | 50,000 | — | — |
| 2026-06-05 | YE, WEIGUO | Chief Operating Officer | Sale | 15,401 | — | — |
| 2026-06-05 | YE, WEIGUO | Chief Operating Officer | Buy | 15,401 | $0.75 | $11550.75 |
| 2026-06-04 | YE, WEIGUO | Chief Operating Officer | Sale | 19,575 | — | — |
| 2026-06-04 | YE, WEIGUO | Chief Operating Officer | Buy | 19,575 | $0.75 | $14681.25 |
| 2026-05-26 | YE, WEIGUO | Chief Operating Officer | Sale | 4,000 | — | — |
| 2026-05-26 | YE, WEIGUO | Chief Operating Officer | Sale | 4,000 | $6.10 | $24400.40 |
| 2026-05-22 | YE, WEIGUO | Chief Operating Officer | Sale | 3,500 | — | — |
| 2026-05-22 | YE, WEIGUO | Chief Operating Officer | Sale | 3,500 | $6.08 | $21280.00 |
| 2026-05-21 | YE, WEIGUO | Chief Operating Officer | Sale | 12,820 | — | — |
| 2026-05-21 | YE, WEIGUO | Chief Operating Officer | Sale | 12,820 | $6.15 | $78843.00 |
| 2026-05-20 | YE, WEIGUO | Chief Operating Officer | Sale | 9,400 | — | — |
| 2026-05-20 | YE, WEIGUO | Chief Operating Officer | Sale | 9,400 | $6.15 | $57810.00 |
| 2026-05-19 | YE, WEIGUO | Chief Operating Officer | Sale | 9,120 | — | — |
| 2026-05-19 | YE, WEIGUO | Chief Operating Officer | Buy | 9,120 | $0.75 | $6840.00 |
| 2026-05-18 | YE, WEIGUO | Chief Operating Officer | Sale | 200 | — | — |
| 2026-05-18 | YE, WEIGUO | Chief Operating Officer | Sale | 200 | $6.62 | $1324.00 |
| 2026-05-15 | YE, WEIGUO | Chief Operating Officer | Sale | 13,100 | — | — |
| 2026-05-15 | YE, WEIGUO | Chief Operating Officer | Buy | 13,100 | $0.75 | $9825.00 |
| 2026-05-14 | ZHANG, PING | Director | Sale | 250,000 | — | — |
| 2026-05-14 | YE, WEIGUO | Chief Operating Officer | Sale | 15,580 | — | — |
| 2026-05-14 | YE, WEIGUO | Chief Operating Officer | Buy | 15,580 | $0.75 | $11685.00 |
| 2026-05-06 | LUO, YING | Director, Chief Executive Officer | Sale | 10,136 | $8.04 | $81493.44 |
| 2026-05-05 | LUO, YING | Director, Chief Executive Officer | Sale | 179 | $8.01 | $1433.79 |
| 2026-05-04 | GNI, GROUP LTD. | 10% Owner | Buy | 2,143,706 | — | — |
| 2026-05-04 | GNI, GROUP LTD. | 10% Owner | Buy | 458,120 | — | — |
| 2026-05-04 | EASTLING, THOMAS WILSON | Chief Financial Officer | Buy | 95,060 | — | — |
| 2026-05-04 | EASTLING, THOMAS WILSON | Chief Financial Officer | Buy | 92,683 | — | — |
| 2026-05-04 | EASTLING, THOMAS WILSON | Chief Financial Officer | Buy | 47,530 | — | — |
| 2026-05-04 | EASTLING, THOMAS WILSON | Chief Financial Officer | Buy | 33,271 | — | — |
| 2026-05-04 | EASTLING, THOMAS WILSON | Chief Financial Officer | Buy | 11,882 | — | — |
| 2026-01-07 | ZHANG, PING | Director | Buy | 100,000 | — | — |
| 2026-01-07 | CHEN, RUOYU | Chief Financial Officer | Buy | 50,000 | — | — |
| 2025-08-18 | WENG, DAN | Director | Buy | 52,000 | — | — |
| 2025-08-05 | ZHANG, PING | Director | Buy | 250,000 | — | — |
| 2025-06-04 | PARRY, RENATE | Director | Buy | 26,000 | — | — |
| 2025-06-04 | NUSSBAUM, RODNEY L | Director | Buy | 26,000 | — | — |
| 2025-06-04 | EPSTEIN, DAVID M. | Director | Buy | 26,000 | — | — |
| 2025-06-04 | EASTLING, THOMAS WILSON | Director | Buy | 26,000 | — | — |
| 2025-06-04 | CARMICHAEL, GORDON | Director | Buy | 26,000 | — | — |
| 2025-05-28 | MA, SONGJIANG | Director, President | Sale | 558 | $10.07 | $5619.06 |
| 2025-05-27 | ZHANG, PING | Director | Buy | 250,000 | — | — |
| 2025-05-27 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.28 | $20560.00 |
| 2025-05-23 | MA, SONGJIANG | Director, President | Sale | 182 | $10.24 | $1863.68 |
| 2025-05-22 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.97 | $21940.00 |
| 2025-05-21 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.83 | $21660.00 |
| 2025-05-20 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.25 | $22500.00 |
| 2025-05-19 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.11 | $22220.00 |
| 2025-05-16 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.31 | $22620.00 |
| 2025-05-15 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.68 | $21360.00 |
| 2025-05-14 | MA, SONGJIANG | Director, President | Sale | 20 | $11.30 | $226.00 |
| 2025-05-13 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.37 | $22740.00 |
| 2025-05-12 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.56 | $21120.00 |
| 2025-04-16 | EASTLING, THOMAS WILSON | Director | Sale | 15,000 | — | — |
| 2025-04-16 | EASTLING, THOMAS WILSON | Director | Buy | 15,000 | $6.93 | $103950.00 |
| 2025-04-01 | YE, WEIGUO | Chief Operating Officer | Sale | 50,000 | — | — |
| 2025-04-01 | YE, WEIGUO | Chief Operating Officer | Buy | 50,000 | $0.75 | $37500.00 |
| 2025-03-27 | YE, WEIGUO | Chief Operating Officer | Sale | 150,000 | — | — |
| 2025-03-27 | YE, WEIGUO | Chief Operating Officer | Buy | 150,000 | $0.75 | $112500.00 |
| 2025-03-26 | YE, WEIGUO | Chief Operating Officer | Sale | 200,000 | — | — |
| 2025-03-26 | YE, WEIGUO | Chief Operating Officer | Buy | 200,000 | $0.75 | $150000.00 |
| 2025-03-24 | YE, WEIGUO | Chief Operating Officer | Sale | 300,000 | — | — |
| 2025-03-24 | YE, WEIGUO | Chief Operating Officer | Buy | 300,000 | $0.75 | $225000.00 |
| 2025-03-21 | MA, SONGJIANG | Director, President | Sale | 174 | $10.00 | $1740.00 |
| 2025-03-20 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.09 | $20180.00 |
| 2025-03-19 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.13 | $20260.00 |
| 2025-03-18 | MA, SONGJIANG | Director, President | Sale | 242 | $10.24 | $2478.08 |
| 2025-03-17 | MA, SONGJIANG | Director, President | Sale | 2,000 | $12.09 | $24180.00 |
| 2025-03-14 | MA, SONGJIANG | Director, President | Sale | 2,000 | $12.31 | $24620.00 |
| 2025-03-13 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.80 | $23600.00 |
| 2025-03-12 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.74 | $23480.00 |
| 2025-03-11 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.40 | $22800.00 |
| 2025-03-10 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.14 | $20280.00 |
| 2025-03-07 | YE, WEIGUO | Chief Operating Officer | Buy | 300,000 | — | — |
| 2025-03-07 | MA, SONGJIANG | Director, President | Sale | 1,906 | $10.13 | $19307.78 |
| 2025-03-07 | MA, SONGJIANG | Director, President | Sale | 53 | $13.03 | $690.59 |
| 2025-03-07 | MA, SONGJIANG | Director, President | Sale | 41 | $12.14 | $497.74 |
| 2025-03-06 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.80 | $21600.00 |
| 2025-03-05 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.98 | $21960.00 |
Frequently asked questions
Are CBIO insiders buying or selling?
Over the transactions on record, CBIO insiders have been net sellers, with about $844519.34 in stock sold across 61 sales, against 11 open-market purchases.
Does insider selling at CBIO mean the stock will fall?
Not by itself. Most executive selling is pre-scheduled through 10b5-1 plans filed months in advance, and insiders sell for diversification, taxes, and liquidity far more often than out of any view on the price. Insider buying is the stronger signal, especially when several insiders buy around the same time, because there is usually only one reason to put personal cash into the stock.
Which CBIO insiders are selling the most?
Recent selling is concentrated in a few names. MA, SONGJIANG accounts for the largest share on record, with about $452102.93 sold. Selling by one or two individuals matters less than broad selling across the whole leadership team, which is the pattern worth watching.