CBIO
Crescent Biopharma, Inc.
NASDAQ: CBIO · HEALTHCARE · BIOTECHNOLOGY
$18.46
-2.44% today
Updated 2026-06-05
Market cap
$495.80M
P/E ratio
—
P/S ratio
41.72x
EPS (TTM)
$-5.88
Dividend yield
—
52W range
$9 – $27
Volume
0.3M
Crescent Biopharma, Inc. (CBIO) Insider transactions
Net insider activity
Net buying (3,614,043 shares)
Buy transactions
26
Sell transactions
74
All transactions
| Date | Insider | Title | Type | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-05-21 | YE, WEIGUO | Chief Operating Officer | Sale | 12,820 | — | — |
| 2026-05-21 | YE, WEIGUO | Chief Operating Officer | Sale | 12,820 | $6.15 | $78843.00 |
| 2026-05-20 | YE, WEIGUO | Chief Operating Officer | Sale | 9,400 | — | — |
| 2026-05-20 | YE, WEIGUO | Chief Operating Officer | Sale | 9,400 | $6.15 | $57810.00 |
| 2026-05-19 | YE, WEIGUO | Chief Operating Officer | Sale | 9,120 | — | — |
| 2026-05-19 | YE, WEIGUO | Chief Operating Officer | Buy | 9,120 | $0.75 | $6840.00 |
| 2026-05-18 | YE, WEIGUO | Chief Operating Officer | Sale | 200 | — | — |
| 2026-05-18 | YE, WEIGUO | Chief Operating Officer | Sale | 200 | $6.62 | $1324.00 |
| 2026-05-15 | YE, WEIGUO | Chief Operating Officer | Sale | 13,100 | — | — |
| 2026-05-15 | YE, WEIGUO | Chief Operating Officer | Buy | 13,100 | $0.75 | $9825.00 |
| 2026-05-14 | ZHANG, PING | Director | Sale | 250,000 | — | — |
| 2026-05-14 | YE, WEIGUO | Chief Operating Officer | Sale | 15,580 | — | — |
| 2026-05-14 | YE, WEIGUO | Chief Operating Officer | Buy | 15,580 | $0.75 | $11685.00 |
| 2026-05-06 | LUO, YING | Director, Chief Executive Officer | Sale | 10,136 | $8.04 | $81493.44 |
| 2026-05-05 | LUO, YING | Director, Chief Executive Officer | Sale | 179 | $8.01 | $1433.79 |
| 2026-05-04 | GNI, GROUP LTD. | 10% Owner | Buy | 2,143,706 | — | — |
| 2026-05-04 | GNI, GROUP LTD. | 10% Owner | Buy | 458,120 | — | — |
| 2026-05-04 | EASTLING, THOMAS WILSON | Chief Financial Officer | Buy | 95,060 | — | — |
| 2026-05-04 | EASTLING, THOMAS WILSON | Chief Financial Officer | Buy | 92,683 | — | — |
| 2026-05-04 | EASTLING, THOMAS WILSON | Chief Financial Officer | Buy | 47,530 | — | — |
| 2026-05-04 | EASTLING, THOMAS WILSON | Chief Financial Officer | Buy | 33,271 | — | — |
| 2026-05-04 | EASTLING, THOMAS WILSON | Chief Financial Officer | Buy | 11,882 | — | — |
| 2026-01-07 | ZHANG, PING | Director | Buy | 100,000 | — | — |
| 2026-01-07 | CHEN, RUOYU | Chief Financial Officer | Buy | 50,000 | — | — |
| 2025-08-18 | WENG, DAN | Director | Buy | 52,000 | — | — |
| 2025-08-05 | ZHANG, PING | Director | Buy | 250,000 | — | — |
| 2025-06-04 | PARRY, RENATE | Director | Buy | 26,000 | — | — |
| 2025-06-04 | NUSSBAUM, RODNEY L | Director | Buy | 26,000 | — | — |
| 2025-06-04 | EPSTEIN, DAVID M. | Director | Buy | 26,000 | — | — |
| 2025-06-04 | EASTLING, THOMAS WILSON | Director | Buy | 26,000 | — | — |
| 2025-06-04 | CARMICHAEL, GORDON | Director | Buy | 26,000 | — | — |
| 2025-05-28 | MA, SONGJIANG | Director, President | Sale | 558 | $10.07 | $5619.06 |
| 2025-05-27 | ZHANG, PING | Director | Buy | 250,000 | — | — |
| 2025-05-27 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.28 | $20560.00 |
| 2025-05-23 | MA, SONGJIANG | Director, President | Sale | 182 | $10.24 | $1863.68 |
| 2025-05-22 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.97 | $21940.00 |
| 2025-05-21 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.83 | $21660.00 |
| 2025-05-20 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.25 | $22500.00 |
| 2025-05-19 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.11 | $22220.00 |
| 2025-05-16 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.31 | $22620.00 |
| 2025-05-15 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.68 | $21360.00 |
| 2025-05-14 | MA, SONGJIANG | Director, President | Sale | 20 | $11.30 | $226.00 |
| 2025-05-13 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.37 | $22740.00 |
| 2025-05-12 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.56 | $21120.00 |
| 2025-04-16 | EASTLING, THOMAS WILSON | Director | Sale | 15,000 | — | — |
| 2025-04-16 | EASTLING, THOMAS WILSON | Director | Buy | 15,000 | $6.93 | $103950.00 |
| 2025-04-01 | YE, WEIGUO | Chief Operating Officer | Sale | 50,000 | — | — |
| 2025-04-01 | YE, WEIGUO | Chief Operating Officer | Buy | 50,000 | $0.75 | $37500.00 |
| 2025-03-27 | YE, WEIGUO | Chief Operating Officer | Sale | 150,000 | — | — |
| 2025-03-27 | YE, WEIGUO | Chief Operating Officer | Buy | 150,000 | $0.75 | $112500.00 |
| 2025-03-26 | YE, WEIGUO | Chief Operating Officer | Sale | 200,000 | — | — |
| 2025-03-26 | YE, WEIGUO | Chief Operating Officer | Buy | 200,000 | $0.75 | $150000.00 |
| 2025-03-24 | YE, WEIGUO | Chief Operating Officer | Sale | 300,000 | — | — |
| 2025-03-24 | YE, WEIGUO | Chief Operating Officer | Buy | 300,000 | $0.75 | $225000.00 |
| 2025-03-21 | MA, SONGJIANG | Director, President | Sale | 174 | $10.00 | $1740.00 |
| 2025-03-20 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.09 | $20180.00 |
| 2025-03-19 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.13 | $20260.00 |
| 2025-03-18 | MA, SONGJIANG | Director, President | Sale | 242 | $10.24 | $2478.08 |
| 2025-03-17 | MA, SONGJIANG | Director, President | Sale | 2,000 | $12.09 | $24180.00 |
| 2025-03-14 | MA, SONGJIANG | Director, President | Sale | 2,000 | $12.31 | $24620.00 |
| 2025-03-13 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.80 | $23600.00 |
| 2025-03-12 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.74 | $23480.00 |
| 2025-03-11 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.40 | $22800.00 |
| 2025-03-10 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.14 | $20280.00 |
| 2025-03-07 | YE, WEIGUO | Chief Operating Officer | Buy | 300,000 | — | — |
| 2025-03-07 | MA, SONGJIANG | Director, President | Sale | 1,906 | $10.13 | $19307.78 |
| 2025-03-07 | MA, SONGJIANG | Director, President | Sale | 53 | $13.03 | $690.59 |
| 2025-03-07 | MA, SONGJIANG | Director, President | Sale | 41 | $12.14 | $497.74 |
| 2025-03-06 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.80 | $21600.00 |
| 2025-03-05 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.98 | $21960.00 |
| 2025-03-04 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.86 | $21720.00 |
| 2025-03-03 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.23 | $22460.00 |
| 2025-02-28 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.41 | $22820.00 |
| 2025-02-27 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.33 | $22660.00 |
| 2025-02-26 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.63 | $23260.00 |
| 2025-02-25 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.37 | $22740.00 |
| 2025-02-24 | MA, SONGJIANG | Director, President | Sale | 1,813 | $10.60 | $19217.80 |
| 2025-02-24 | MA, SONGJIANG | Director, President | Sale | 187 | $11.52 | $2154.24 |
| 2025-02-21 | MA, SONGJIANG | Director, President | Sale | 1,818 | $11.84 | $21525.12 |
| 2025-02-21 | MA, SONGJIANG | Director, President | Sale | 182 | $12.60 | $2293.20 |
| 2025-02-20 | MA, SONGJIANG | Director, President | Sale | 2,000 | $12.40 | $24800.00 |
| 2025-02-19 | MA, SONGJIANG | Director, President | Sale | 2,000 | $12.29 | $24580.00 |
| 2025-02-18 | MA, SONGJIANG | Director, President | Sale | 2,000 | $12.49 | $24980.00 |
| 2025-02-14 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.94 | $23880.00 |
| 2025-02-13 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.69 | $23380.00 |
| 2025-02-12 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.49 | $22980.00 |
| 2025-02-11 | MA, SONGJIANG | Director, President | Sale | 1,878 | $11.52 | $21634.56 |
| 2025-02-10 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.90 | $23800.00 |
| 2025-02-07 | MA, SONGJIANG | Director, President | Sale | 2,000 | $12.16 | $24320.00 |
| 2025-02-06 | MA, SONGJIANG | Director, President | Sale | 2,000 | $12.85 | $25700.00 |
| 2025-02-05 | MA, SONGJIANG | Director, President | Sale | 1,980 | $12.39 | $24532.20 |
| 2025-02-05 | MA, SONGJIANG | Director, President | Sale | 20 | $12.84 | $256.80 |
| 2025-02-04 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.62 | $23240.00 |
| 2025-02-03 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.47 | $22940.00 |
| 2025-01-31 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.51 | $23020.00 |
| 2025-01-30 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.37 | $22740.00 |
| 2025-01-29 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.43 | $22860.00 |
| 2025-01-28 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.51 | $23020.00 |
| 2025-01-27 | MA, SONGJIANG | Director, President | Sale | 2,000 | $11.18 | $22360.00 |
| 2025-01-24 | MA, SONGJIANG | Director, President | Sale | 2,000 | $10.89 | $21780.00 |
Frequently asked questions
Are CBIO insiders buying or selling?
Over the transactions on record, CBIO insiders have been net sellers, with about $1.30M in stock sold across 74 sales, against 8 open-market purchases.
Does insider selling at CBIO mean the stock will fall?
Not by itself. Most executive selling is pre-scheduled through 10b5-1 plans filed months in advance, and insiders sell for diversification, taxes, and liquidity far more often than out of any view on the price. Insider buying is the stronger signal, especially when several insiders buy around the same time, because there is usually only one reason to put personal cash into the stock.
Which CBIO insiders are selling the most?
Recent selling is concentrated in a few names. MA, SONGJIANG accounts for the largest share on record, with about $1.08M sold. Selling by one or two individuals matters less than broad selling across the whole leadership team, which is the pattern worth watching.