Assembly Biosciences Inc
NASDAQ: ASMB · HEALTHCARE · BIOTECHNOLOGY
Updated 2026-10-29
Assembly Biosciences Inc (ASMB) Stock Valuation Analysis
Fair value estimate, historical valuation range, and quality signals for ASMB.
Current price exceeds what fundamentals support. Risk/reward skewed unfavorably.
ASMB historical valuation range
Where current P/E sits in ASMB's own 5Y range.
ASMB intrinsic value (DCF)
DCF-based fair value estimate vs current market price.
Intrinsic value calculated using discounted cash flow (DCF) model based on projected free cash flows, discount rate, and terminal growth assumptions. A positive margin of safety indicates the current price is below estimated fair value, providing a cushion against estimation error.
ASMB valuation signals
Quick-read green flags, caution flags, and risks based on current metrics.
P/E Ratio — History
Current: 19.32x
P/S Ratio — History
Current: 5.47x
Is ASMB overvalued in 2026?
Assembly Biosciences Inc (ASMB) currently trades at $20.86 per share with a market capitalization of $409,044,000.00. Based on our multi-factor framework, the stock appears richly valued with a Smart Value Score of 37/100. This score blends growth quality, financial health, and price attractiveness into a single institutional-grade read.
The stock trades at a P/E ratio of 19.3x, below its 5-year median of 22.8x.
Looking at its own history, ASMB is currently trading cheaper than 83% of the last 5Y on P/E. This places it in the 17th percentile of its historical range, a level that has historically coincided with attractive entry points.
Our discounted cash flow model estimates ASMB's intrinsic value at $40.62 per share, against the current market price of $20.86. This implies a margin of safety of +32.64%. A meaningful cushion exists against model error, making this a reasonable risk-adjusted entry.
The Piotroski F-Score of 5/9 puts financial quality in a middling range, neither a standout strength nor an obvious red flag.
Bottom line: ASMB appears richly valued on our framework, with a Smart Value Score of 37/100. At current levels the risk/reward is skewed against the buyer. A materially lower price or significant operational improvement would be needed to change the picture.
Frequently asked questions
Is ASMB overvalued?
ASMB scores 37/100 on our Smart Value Score (Grade D), a weak overall profile. The DCF also shows a positive margin of safety, so price and fundamentals line up reasonably well.
What is ASMB's fair value?
Our DCF model estimates ASMB's intrinsic value at $40.62 per share, versus the current price of $20.86, a margin of safety of +32.64%. Fair value is the present value of the cash flows we project the business to produce, so a price below it means the market is pricing the stock below that conservative estimate.
What P/E ratio does ASMB trade at?
ASMB trades at a P/E of 19.3x on trailing twelve-month earnings, against a 5-year median of 22.8x. P/E is what you pay per dollar of profit, and sitting below its own median means the stock is cheaper than usual relative to its earnings.
Is ASMB a buy based on valuation?
Our Smart Value rating for ASMB is Sell, from a Smart Value Score of 37/100 that blends growth, quality, and valuation. The profile skews cautious, and a better price or clearer operating improvement would strengthen the case. This is research to inform your decision, not personalized financial advice.
How does ASMB's valuation compare to its history?
On P/E, ASMB sits in the 17th percentile of its own 5Y range, historically cheap relative to where it has traded. A low percentile means today's multiple is near the bottom of its historical band.
What is ASMB's Smart Value Score?
ASMB's Smart Value Score is 37/100. It is a proprietary WallStSmart metric blending growth quality, financial health, and valuation into a single 0-100 read, and scores above 75 are rare, signaling strong multi-factor alignment.