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APLS

Apellis Pharmaceuticals Inc

NASDAQ: APLS · HEALTHCARE · BIOTECHNOLOGY

$41.02
+0.00% today

Updated 2026-05-14

Market cap
$5.25B
P/E ratio
38.34
P/S ratio
4.75x
EPS (TTM)
$1.07
Dividend yield
52W range
$16 – $41
Volume
7.4M

Apellis Pharmaceuticals Inc (APLS) Financial statements

SEC filings — annual and quarterly data.

Profit margin
2.23%
Operating margin
5.52%
ROE
33.22%
ROA
10.90%
Debt/equity
1.18x

Margin trends — annual

Gross margin Operating margin Profit margin
YearRevenueNet incomeGross marginOp. marginProfit margin
2013$-3.96M
2014$0.00$-10.79M
2015$0.00$-46.52M
2016$0.00$-27.12M
2017$0.00$-51.01M
2018$0.00$-127.50M
2019$0.00$-304.71M
2020$250.65M$-344.87M90.01%-85.27%-137.59%
2021$66.56M$-746.35M92.19%-805.67%-1,121.27%
2022$75.42M$-652.17M92.53%-788.38%-864.70%
2023$396.59M$-528.63M85.25%-130.39%-133.29%
2024$781.37M$-197.88M84.93%-21.11%-25.32%
2025$1.00B$22.39M89.81%5.52%2.23%

Frequently asked questions

What is Apellis Pharmaceuticals Inc's revenue?

Apellis Pharmaceuticals Inc's trailing twelve-month revenue is $1.11B. Revenue is the top line the whole model builds on, and at this scale the question shifts from how fast it grows to whether margins hold as it compounds.

How profitable is APLS?

In its most recent fiscal year, APLS ran a gross margin of 89.81%, an operating margin of 5.52%, and a net margin of 2.23%. Margins this high mean most of each extra dollar of revenue drops through to profit, which is the signature of real pricing power.

How much free cash flow does APLS generate?

APLS produced $45.01M in free cash flow in its most recent fiscal year. Free cash flow is what is left after running and reinvesting in the business, and it is the cash that actually funds buybacks, dividends, and a stronger balance sheet.

Is APLS's balance sheet healthy?

APLS holds $411.29M in cash and equivalents against $452.83M in long-term debt, on $228.54M of shareholder equity. That debt is best read against the cash flow the business throws off each year.