WallStSmart
ABUS

Arbutus Biopharma Corp

NASDAQ: ABUS · HEALTHCARE · BIOTECHNOLOGY

$4.32
+0.70% today

Updated 2026-10-28

Market cap
$646.82M
P/E ratio
5.34
P/S ratio
3.56x
EPS (TTM)
$0.79
Dividend yield
—
52W range
$4 – $5
Volume
5.9M

Arbutus Biopharma Corp (ABUS) Stock Valuation Analysis

Fair value estimate, historical valuation range, and quality signals for ABUS.

WallStSmart Verdict
Overvalued

Current price exceeds what fundamentals support. Risk/reward skewed unfavorably.

Smart Value Score: 44 / 100
P/E (TTM)
5.3x
vs 5Y median of 5.7x
PEG
—
—
Margin of Safety
—
DCF limited for this profile
EV / EBITDA
5.9x

ABUS historical valuation range

Where current P/E sits in ABUS's own 5Y range.

NOW
5.1x
5Y Low
5.4x
25th
5.7x
Median
6.3x
75th
6.5x
5Y High
ABUS is trading cheaper than 75% of the last 5Y.
25th percentile · Below median

ABUS intrinsic value (DCF)

DCF-based fair value estimate vs current market price.

DCF has limited applicability for ABUS

Standard discounted cash flow models produce unreliable output for unprofitable or near-breakeven companies. Revenue-based multiples such as P/S and EV/Sales, combined with the historical valuation position above, give a more reliable read for this stock.

Intrinsic value calculated using discounted cash flow (DCF) model based on projected free cash flows, discount rate, and terminal growth assumptions. A positive margin of safety indicates the current price is below estimated fair value, providing a cushion against estimation error.

ABUS valuation signals

Quick-read green flags, caution flags, and risks based on current metrics.

!
P/E in mid-range
P/E sits at the 25th percentile of the 5Y range. Neither cheap nor rich historically.
!
DCF limited applicability
Company profile produces unstable DCF output. Lean on P/S, EV/Sales, and historical valuation position instead of intrinsic value for this stock.

P/E Ratio — History

Current: 5.34x

P/S Ratio — History

Current: 3.56x

Is ABUS overvalued in 2026?

Arbutus Biopharma Corp (ABUS) currently trades at $4.32 per share with a market capitalization of $646,824,000.00. Based on our multi-factor framework, the stock appears richly valued with a Smart Value Score of 44/100. This score blends growth quality, financial health, and price attractiveness into a single institutional-grade read.

The stock trades at a P/E ratio of 5.3x, below its 5-year median of 5.7x.

Looking at its own history, ABUS is currently trading cheaper than 75% of the last 5Y on P/E. This places it in the 25th percentile of its historical range, a reasonable but unremarkable position.

A standard DCF model does not produce reliable output for ABUS under current conditions. For unprofitable or near-breakeven companies, revenue-based multiples such as EV/Sales and historical P/S percentile are more informative than intrinsic value calculations.

The Piotroski F-Score of 4/9 puts financial quality in a middling range, neither a standout strength nor an obvious red flag.

Bottom line: ABUS appears richly valued on our framework, with a Smart Value Score of 44/100. At current levels the risk/reward is skewed against the buyer. A materially lower price or significant operational improvement would be needed to change the picture.

Frequently asked questions

Is ABUS overvalued?

ABUS scores 44/100 on our Smart Value Score (Grade D), a weak overall profile. A standard DCF is unreliable here given the profitability profile, so valuation leans on revenue-based measures like EV/Sales and the P/S percentile below.

What is ABUS's fair value?

A standard DCF is unreliable for ABUS given its current profitability profile. Revenue-based approaches like EV/Sales or the historical P/S percentile are more informative for this stock.

What P/E ratio does ABUS trade at?

ABUS trades at a P/E of 5.3x on trailing twelve-month earnings, against a 5-year median of 5.7x. P/E is what you pay per dollar of profit, and sitting below its own median means the stock is cheaper than usual relative to its earnings.

Is ABUS a buy based on valuation?

Our Smart Value rating for ABUS is Sell, from a Smart Value Score of 44/100 that blends growth, quality, and valuation. The profile skews cautious, and a better price or clearer operating improvement would strengthen the case. This is research to inform your decision, not personalized financial advice.

How does ABUS's valuation compare to its history?

On P/E, ABUS sits in the 25th percentile of its own 5Y range, below its long-run median relative to where it has traded. A low percentile means today's multiple is near the bottom of its historical band.

What is ABUS's Smart Value Score?

ABUS's Smart Value Score is 44/100. It is a proprietary WallStSmart metric blending growth quality, financial health, and valuation into a single 0-100 read, and scores above 75 are rare, signaling strong multi-factor alignment.