WallStSmart

Puma Biotechnology Inc (PBYI)vsRegeneron Pharmaceuticals Inc (REGN)

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Smart Verdict

WallStSmart Research — data-driven comparison

Regeneron Pharmaceuticals Inc generates 6181% more annual revenue ($14.34B vs $228.37M). REGN leads profitability with a 31.4% profit margin vs 13.6%. PBYI appears more attractively valued with a PEG of 0.03. PBYI earns a higher WallStSmart Score of 71/100 (B).

PBYI

Strong Buy

71

out of 100

Grade: B

Growth: 5.3Profit: 8.0Value: 7.3Quality: 5.0

REGN

Buy

58

out of 100

Grade: C

Growth: 4.0Profit: 7.5Value: 7.3Quality: 7.3
Piotroski: 3/9Altman Z: 4.68
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

PBYISignificantly Overvalued (-60.0%)

Margin of Safety

-60.0%

Fair Value

$4.15

Current Price

$6.33

$2.18 premium

UndervaluedFair: $4.15Overvalued
REGNSignificantly Overvalued (-165.8%)

Margin of Safety

-165.8%

Fair Value

$281.93

Current Price

$749.47

$467.54 premium

UndervaluedFair: $281.93Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

PBYI6 strengths · Avg: 8.8/10
PEG RatioValuation
0.0310/10

Growing faster than its price suggests

P/E RatioValuation
10.3x10/10

Attractively priced relative to earnings

Return on EquityProfitability
28.0%9/10

Every $100 of equity generates 28 in profit

Price/BookValuation
2.4x8/10

Reasonable price relative to book value

Operating MarginProfitability
22.7%8/10

Strong operational efficiency at 22.7%

Revenue GrowthGrowth
27.7%8/10

Revenue surging 27.7% year-over-year

REGN6 strengths · Avg: 8.8/10
Profit MarginProfitability
31.4%10/10

Keeps 31 of every $100 in revenue as profit

Altman Z-ScoreHealth
4.6810/10

Safe zone — low bankruptcy risk

Market CapQuality
$78.41B9/10

Large-cap with strong market position

P/E RatioValuation
17.9x8/10

Attractively priced relative to earnings

Price/BookValuation
2.5x8/10

Reasonable price relative to book value

Operating MarginProfitability
23.1%8/10

Strong operational efficiency at 23.1%

Areas to Watch

PBYI2 concerns · Avg: 2.5/10
Market CapQuality
$317.98M3/10

Smaller company, higher risk/reward

EPS GrowthGrowth
-34.4%2/10

Earnings declined 34.4%

REGN4 concerns · Avg: 3.3/10
PEG RatioValuation
1.564/10

Expensive relative to growth rate

Revenue GrowthGrowth
2.5%4/10

2.5% revenue growth

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

EPS GrowthGrowth
-2.6%2/10

Earnings declined 2.6%

Comparative Analysis Report

WallStSmart Research

Bull Case : PBYI

The strongest argument for PBYI centers on PEG Ratio, P/E Ratio, Return on Equity. Revenue growth of 27.7% demonstrates continued momentum. PEG of 0.03 suggests the stock is reasonably priced for its growth.

Bull Case : REGN

The strongest argument for REGN centers on Profit Margin, Altman Z-Score, Market Cap. Profitability is solid with margins at 31.4% and operating margin at 23.1%.

Bear Case : PBYI

The primary concerns for PBYI are Market Cap, EPS Growth.

Bear Case : REGN

The primary concerns for REGN are PEG Ratio, Revenue Growth, Piotroski F-Score.

Key Dynamics to Monitor

PBYI profiles as a growth stock while REGN is a value play — different risk/reward profiles.

PBYI carries more volatility with a beta of 1.27 — expect wider price swings.

PBYI is growing revenue faster at 27.7% — sustainability is the question.

REGN generates stronger free cash flow (922M), providing more financial flexibility.

Bottom Line

PBYI scores higher overall (71/100 vs 58/100) and 27.7% revenue growth. Both earn "Strong Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Puma Biotechnology Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Puma Biotechnology, Inc., a biopharmaceutical company, focuses on the development and commercialization of products to improve cancer care in the United States and internationally. The company is headquartered in Los Angeles, California.

Regeneron Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Regeneron Pharmaceuticals, Inc. is an American biotechnology company headquartered in Westchester County, New York. Originally focused on neurotrophic factors and their regenerative capabilities, giving rise to its name, the company then branched out into the study of both cytokine and tyrosine kinase receptors.

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