WallStSmart

Regeneron Pharmaceuticals Inc (REGN)vsVertex Pharmaceuticals Inc (VRTX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Regeneron Pharmaceuticals Inc generates 23% more annual revenue ($15.53B vs $12.59B). VRTX leads profitability with a 35.0% profit margin vs 27.9%. REGN appears more attractively valued with a PEG of 1.31. REGN earns a higher WallStSmart Score of 66/100 (B-).

REGN

Strong Buy

66

out of 100

Grade: B-

Growth: 5.3Profit: 8.0Value: 7.3Quality: 8.5
Piotroski: 2/9Altman Z: 4.44

VRTX

Buy

64

out of 100

Grade: C+

Growth: 6.7Profit: 9.0Value: 6.7Quality: 8.5
Piotroski: 3/9Altman Z: 3.61
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

REGNUndervalued (+44.7%)

Margin of Safety

+44.7%

Fair Value

$1400.68

Current Price

$789.45

$611.23 discount

UndervaluedFair: $1400.68Overvalued
VRTXUndervalued (+46.3%)

Margin of Safety

+46.3%

Fair Value

$960.82

Current Price

$516.34

$444.48 discount

UndervaluedFair: $960.82Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

REGN6 strengths · Avg: 9.3/10
Operating MarginProfitability
33.1%10/10

Strong operational efficiency at 33.1%

Debt/EquityHealth
0.0610/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
4.4410/10

Safe zone — low bankruptcy risk

Market CapQuality
$80.46B9/10

Large-cap with strong market position

Profit MarginProfitability
27.9%9/10

Keeps 28 of every $100 in revenue as profit

Price/BookValuation
2.5x8/10

Reasonable price relative to book value

VRTX6 strengths · Avg: 9.7/10
Profit MarginProfitability
35.0%10/10

Keeps 35 of every $100 in revenue as profit

Operating MarginProfitability
38.1%10/10

Strong operational efficiency at 38.1%

Debt/EquityHealth
0.1010/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
3.6110/10

Safe zone — low bankruptcy risk

Market CapQuality
$130.56B9/10

Large-cap with strong market position

Return on EquityProfitability
21.8%9/10

Every $100 of equity generates 22 in profit

Areas to Watch

REGN2 concerns · Avg: 2.5/10
Piotroski F-ScoreQuality
2/93/10

Weak financial health signals

EPS GrowthGrowth
-4.5%2/10

Earnings declined 4.5%

VRTX3 concerns · Avg: 3.7/10
PEG RatioValuation
1.894/10

Expensive relative to growth rate

P/E RatioValuation
30.0x4/10

Moderate valuation

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Comparative Analysis Report

WallStSmart Research

Bull Case : REGN

The strongest argument for REGN centers on Operating Margin, Debt/Equity, Altman Z-Score. Profitability is solid with margins at 27.9% and operating margin at 33.1%. Revenue growth of 16.7% demonstrates continued momentum.

Bull Case : VRTX

The strongest argument for VRTX centers on Profit Margin, Operating Margin, Debt/Equity. Profitability is solid with margins at 35.0% and operating margin at 38.1%. Revenue growth of 12.5% demonstrates continued momentum.

Bear Case : REGN

The primary concerns for REGN are Piotroski F-Score, EPS Growth.

Bear Case : VRTX

The primary concerns for VRTX are PEG Ratio, P/E Ratio, Piotroski F-Score.

Key Dynamics to Monitor

REGN profiles as a growth stock while VRTX is a mature play — different risk/reward profiles.

VRTX carries more volatility with a beta of 0.32 — expect wider price swings.

REGN is growing revenue faster at 16.7% — sustainability is the question.

VRTX generates stronger free cash flow (1.0B), providing more financial flexibility.

Bottom Line

REGN scores higher overall (66/100 vs 64/100), backed by strong 27.9% margins and 16.7% revenue growth. VRTX offers better value entry with a 46.3% margin of safety. Both earn "Strong Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Regeneron Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Regeneron Pharmaceuticals, Inc. is an American biotechnology company headquartered in Westchester County, New York. Originally focused on neurotrophic factors and their regenerative capabilities, giving rise to its name, the company then branched out into the study of both cytokine and tyrosine kinase receptors.

Vertex Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Vertex Pharmaceuticals, Inc. is an American biopharmaceutical company based in Boston, Massachusetts.

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