WallStSmart

Mediwound Ltd (MDWD)vsVertex Pharmaceuticals Inc (VRTX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Vertex Pharmaceuticals Inc generates 86834% more annual revenue ($12.59B vs $14.48M). VRTX leads profitability with a 35.0% profit margin vs -180.3%. VRTX earns a higher WallStSmart Score of 64/100 (C+).

MDWD

Avoid

18

out of 100

Grade: F

Growth: 2.7Profit: 2.0Value: 6.7Quality: 6.5
Piotroski: 4/9Altman Z: -3.32

VRTX

Buy

64

out of 100

Grade: C+

Growth: 6.7Profit: 9.0Value: 6.7Quality: 8.5
Piotroski: 3/9Altman Z: 3.61
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

MDWDUndervalued (+54.2%)

Margin of Safety

+54.2%

Fair Value

$37.69

Current Price

$14.19

$23.50 discount

UndervaluedFair: $37.69Overvalued
VRTXUndervalued (+50.1%)

Margin of Safety

+50.1%

Fair Value

$971.64

Current Price

$484.83

$486.81 discount

UndervaluedFair: $971.64Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

MDWD1 strengths · Avg: 9.0/10
Debt/EquityHealth
0.209/10

Conservative balance sheet, low leverage

VRTX6 strengths · Avg: 9.5/10
Profit MarginProfitability
35.0%10/10

Keeps 35 of every $100 in revenue as profit

Operating MarginProfitability
38.1%10/10

Strong operational efficiency at 38.1%

Altman Z-ScoreHealth
3.6110/10

Safe zone — low bankruptcy risk

Market CapQuality
$121.26B9/10

Large-cap with strong market position

Return on EquityProfitability
22.4%9/10

Every $100 of equity generates 22 in profit

Debt/EquityHealth
0.109/10

Conservative balance sheet, low leverage

Areas to Watch

MDWD4 concerns · Avg: 2.8/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$182.76M3/10

Smaller company, higher risk/reward

Return on EquityProfitability
-63.0%2/10

ROE of -63.0% — below average capital efficiency

Revenue GrowthGrowth
-62.7%2/10

Revenue declined 62.7%

VRTX3 concerns · Avg: 3.7/10
PEG RatioValuation
1.624/10

Expensive relative to growth rate

P/E RatioValuation
27.9x4/10

Moderate valuation

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Comparative Analysis Report

WallStSmart Research

Bull Case : MDWD

The strongest argument for MDWD centers on Debt/Equity.

Bull Case : VRTX

The strongest argument for VRTX centers on Profit Margin, Operating Margin, Altman Z-Score. Profitability is solid with margins at 35.0% and operating margin at 38.1%. Revenue growth of 12.5% demonstrates continued momentum.

Bear Case : MDWD

The primary concerns for MDWD are EPS Growth, Market Cap, Return on Equity.

Bear Case : VRTX

The primary concerns for VRTX are PEG Ratio, P/E Ratio, Piotroski F-Score.

Key Dynamics to Monitor

MDWD profiles as a turnaround stock while VRTX is a mature play — different risk/reward profiles.

VRTX carries more volatility with a beta of 0.30 — expect wider price swings.

VRTX is growing revenue faster at 12.5% — sustainability is the question.

VRTX generates stronger free cash flow (1.3B), providing more financial flexibility.

Bottom Line

VRTX scores higher overall (64/100 vs 18/100), backed by strong 35.0% margins and 12.5% revenue growth. MDWD offers better value entry with a 54.2% margin of safety. Both earn "Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Mediwound Ltd

HEALTHCARE · BIOTECHNOLOGY · USA

MediWound Ltd., a biopharmaceutical company, develops, manufactures and markets new and biotherapeutic solutions for tissue repair and regeneration. The company is headquartered in Yavne, Israel.

Vertex Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Vertex Pharmaceuticals, Inc. is an American biopharmaceutical company based in Boston, Massachusetts.

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