WallStSmart

Legend Biotech Corp (LEGN)vsVertex Pharmaceuticals Inc (VRTX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Vertex Pharmaceuticals Inc generates 1005% more annual revenue ($12.59B vs $1.14B). VRTX leads profitability with a 35.0% profit margin vs -22.0%. VRTX earns a higher WallStSmart Score of 64/100 (C+).

LEGN

Hold

36

out of 100

Grade: F

Growth: 8.0Profit: 2.0Value: 5.0Quality: 5.5
Piotroski: 2/9Altman Z: -0.24

VRTX

Buy

64

out of 100

Grade: C+

Growth: 6.7Profit: 9.0Value: 6.7Quality: 8.5
Piotroski: 3/9Altman Z: 3.61
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

Intrinsic value data unavailable for LEGN.

VRTXUndervalued (+50.1%)

Margin of Safety

+50.1%

Fair Value

$971.64

Current Price

$496.07

$475.57 discount

UndervaluedFair: $971.64Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

LEGN1 strengths · Avg: 10.0/10
Revenue GrowthGrowth
56.5%10/10

Revenue surging 56.5% year-over-year

VRTX6 strengths · Avg: 9.5/10
Profit MarginProfitability
35.0%10/10

Keeps 35 of every $100 in revenue as profit

Operating MarginProfitability
38.1%10/10

Strong operational efficiency at 38.1%

Altman Z-ScoreHealth
3.6110/10

Safe zone — low bankruptcy risk

Market CapQuality
$121.26B9/10

Large-cap with strong market position

Return on EquityProfitability
22.4%9/10

Every $100 of equity generates 22 in profit

Debt/EquityHealth
0.109/10

Conservative balance sheet, low leverage

Areas to Watch

LEGN4 concerns · Avg: 2.8/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Piotroski F-ScoreQuality
2/93/10

Weak financial health signals

Return on EquityProfitability
-25.9%2/10

ROE of -25.9% — below average capital efficiency

Free Cash FlowQuality
$-111.33M2/10

Negative free cash flow — burning cash

VRTX3 concerns · Avg: 3.7/10
PEG RatioValuation
1.624/10

Expensive relative to growth rate

P/E RatioValuation
27.9x4/10

Moderate valuation

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Comparative Analysis Report

WallStSmart Research

Bull Case : LEGN

The strongest argument for LEGN centers on Revenue Growth. Revenue growth of 56.5% demonstrates continued momentum.

Bull Case : VRTX

The strongest argument for VRTX centers on Profit Margin, Operating Margin, Altman Z-Score. Profitability is solid with margins at 35.0% and operating margin at 38.1%. Revenue growth of 12.5% demonstrates continued momentum.

Bear Case : LEGN

The primary concerns for LEGN are EPS Growth, Piotroski F-Score, Return on Equity.

Bear Case : VRTX

The primary concerns for VRTX are PEG Ratio, P/E Ratio, Piotroski F-Score.

Key Dynamics to Monitor

LEGN profiles as a hypergrowth stock while VRTX is a mature play — different risk/reward profiles.

LEGN carries more volatility with a beta of 0.34 — expect wider price swings.

LEGN is growing revenue faster at 56.5% — sustainability is the question.

VRTX generates stronger free cash flow (1.3B), providing more financial flexibility.

Bottom Line

VRTX scores higher overall (64/100 vs 36/100), backed by strong 35.0% margins and 12.5% revenue growth. Both earn "Buy" and "Hold" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Legend Biotech Corp

HEALTHCARE · BIOTECHNOLOGY · USA

Legend Biotech Corporation, a clinical-stage biopharmaceutical company, is dedicated to the discovery and development of new cell therapies for oncology and other indications in North America and internationally.

Vertex Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Vertex Pharmaceuticals, Inc. is an American biopharmaceutical company based in Boston, Massachusetts.

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