WallStSmart

Jazz Pharmaceuticals PLC (JAZZ)vsVertex Pharmaceuticals Inc (VRTX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Vertex Pharmaceuticals Inc generates 174% more annual revenue ($12.59B vs $4.60B). VRTX leads profitability with a 35.0% profit margin vs 20.4%. JAZZ appears more attractively valued with a PEG of 0.96. JAZZ earns a higher WallStSmart Score of 72/100 (B).

JAZZ

Strong Buy

72

out of 100

Grade: B

Growth: 6.0Profit: 8.0Value: 8.7Quality: 5.0
Piotroski: 4/9Altman Z: 0.87

VRTX

Buy

64

out of 100

Grade: C+

Growth: 6.7Profit: 9.0Value: 6.7Quality: 8.5
Piotroski: 3/9Altman Z: 3.61
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

JAZZUndervalued (+51.8%)

Margin of Safety

+51.8%

Fair Value

$344.71

Current Price

$245.80

$98.91 discount

UndervaluedFair: $344.71Overvalued
VRTXUndervalued (+46.5%)

Margin of Safety

+46.5%

Fair Value

$963.47

Current Price

$515.44

$448.03 discount

UndervaluedFair: $963.47Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

JAZZ5 strengths · Avg: 8.2/10
Profit MarginProfitability
20.4%9/10

Keeps 20 of every $100 in revenue as profit

PEG RatioValuation
0.968/10

Growing faster than its price suggests

P/E RatioValuation
16.4x8/10

Attractively priced relative to earnings

Operating MarginProfitability
26.9%8/10

Strong operational efficiency at 26.9%

Revenue GrowthGrowth
15.5%8/10

15.5% revenue growth

VRTX6 strengths · Avg: 9.7/10
Profit MarginProfitability
35.0%10/10

Keeps 35 of every $100 in revenue as profit

Operating MarginProfitability
38.1%10/10

Strong operational efficiency at 38.1%

Debt/EquityHealth
0.1010/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
3.6110/10

Safe zone — low bankruptcy risk

Market CapQuality
$130.56B9/10

Large-cap with strong market position

Return on EquityProfitability
21.8%9/10

Every $100 of equity generates 22 in profit

Areas to Watch

JAZZ2 concerns · Avg: 3.0/10
EPS GrowthGrowth
3.2%4/10

3.2% earnings growth

Altman Z-ScoreHealth
0.872/10

Distress zone — elevated risk

VRTX3 concerns · Avg: 3.7/10
PEG RatioValuation
1.894/10

Expensive relative to growth rate

P/E RatioValuation
30.0x4/10

Moderate valuation

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Comparative Analysis Report

WallStSmart Research

Bull Case : JAZZ

The strongest argument for JAZZ centers on Profit Margin, PEG Ratio, P/E Ratio. Profitability is solid with margins at 20.4% and operating margin at 26.9%. Revenue growth of 15.5% demonstrates continued momentum.

Bull Case : VRTX

The strongest argument for VRTX centers on Profit Margin, Operating Margin, Debt/Equity. Profitability is solid with margins at 35.0% and operating margin at 38.1%. Revenue growth of 12.5% demonstrates continued momentum.

Bear Case : JAZZ

The primary concerns for JAZZ are EPS Growth, Altman Z-Score.

Bear Case : VRTX

The primary concerns for VRTX are PEG Ratio, P/E Ratio, Piotroski F-Score.

Key Dynamics to Monitor

JAZZ profiles as a growth stock while VRTX is a mature play — different risk/reward profiles.

JAZZ carries more volatility with a beta of 0.36 — expect wider price swings.

JAZZ is growing revenue faster at 15.5% — sustainability is the question.

VRTX generates stronger free cash flow (1.0B), providing more financial flexibility.

Bottom Line

JAZZ scores higher overall (72/100 vs 64/100), backed by strong 20.4% margins and 15.5% revenue growth. VRTX offers better value entry with a 46.5% margin of safety. Both earn "Strong Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Jazz Pharmaceuticals PLC

HEALTHCARE · BIOTECHNOLOGY · USA

Jazz Pharmaceuticals plc, a biopharmaceutical company, identifies, develops, and markets pharmaceutical products for various unmet medical needs in the United States, Europe, and internationally. The company is headquartered in Dublin, Ireland.

Vertex Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Vertex Pharmaceuticals, Inc. is an American biopharmaceutical company based in Boston, Massachusetts.

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